Mollie Freedman-Weiss

ORCID: 0000-0002-2443-7798
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About
Contact & Profiles
Research Areas
  • Opioid Use Disorder Treatment
  • Anesthesia and Pain Management
  • Diversity and Career in Medicine
  • Cerebrospinal fluid and hydrocephalus
  • Pancreatic and Hepatic Oncology Research
  • Congenital Anomalies and Fetal Surgery
  • Innovations in Medical Education
  • Spinal Dysraphism and Malformations
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Pain Management and Opioid Use
  • Congenital Diaphragmatic Hernia Studies
  • Neonatal Respiratory Health Research
  • Gastrointestinal Tumor Research and Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Hospital Admissions and Outcomes
  • Neuroendocrine Tumor Research Advances
  • Healthcare professionals’ stress and burnout
  • Sleep and Work-Related Fatigue
  • Esophageal and GI Pathology
  • Inhalation and Respiratory Drug Delivery
  • Energy Harvesting in Wireless Networks
  • Vascular Malformations and Hemangiomas
  • Ergonomics and Musculoskeletal Disorders
  • Vascular Anomalies and Treatments
  • Medical Education and Admissions

Cornell University
2025

Yale University
2018-2023

Bloomberg (United States)
2023

Johns Hopkins University
2023

Geisinger Medical Center
2011

Reliance on prescription opioids for postprocedural analgesia has contributed to the opioid epidemic. With implementation of electronic medical record (EMR) systems, there been increasing use computerized order entry systems medication prescriptions, which is now more common than handwritten prescriptions. The EMR can autopopulate a default number pills prescribed, and 1 potential method alter prescriber behavior change presented via system.To investigate association lowering when...

10.1001/jamasurg.2018.2083 article EN JAMA Surgery 2018-07-19

Objective: To investigate the occurrence, nature, and reporting of sexual harassment in surgical training to understand why trainees who experience might not report it. This information will inform ways overcome barriers harassment. Summary/ Background Data: Sexual workplace is a known phenomenon with reports high frequency medical field. Aspects leave especially vulnerable harassing behavior. The characteristics reasons for its underreporting have yet be studied on national level this...

10.1097/sla.0000000000003295 article EN Annals of Surgery 2019-04-05

Ampullary adenocarcinoma is a rare malignant neoplasm that arises within the duodenal ampullary complex. The role of adjuvant therapy (AT) in treatment has not been clearly defined.To determine if long-term survival after curative-intent resection may be improved by selection patients for AT directed histologic subtype.This multinational, retrospective cohort study was conducted at 12 institutions from April 1, 2000, to July 31, 2017, among 357 with resected, nonmetastatic receiving surgery...

10.1001/jamasurg.2019.1170 article EN JAMA Surgery 2019-05-29

Gastric bypass surgery is a highly effective therapy for long-term weight loss in severely obese patients, but carries significant perioperative risks including infection, wound dehiscence, and leaks from staple breakdown. Iron status can affect immune function healing, thus may influence peri-operative complications. Common mutations the HFE gene, gene responsible iron overload disorder hereditary hemochromatosis, impact status. We analyzed 1064 extremely Caucasian individuals who underwent...

10.1186/1754-9493-5-1 article EN cc-by Patient Safety in Surgery 2011-01-01

Structural fetal diseases, such as congenital diaphragmatic hernia (CDH) can be diagnosed prenatally. Neonates with CDH are healthy in utero gas exchange is managed by the placenta, but impaired lung function results critical illness from time a baby takes its first breath. MicroRNA (miR) 200b and downstream targets TGF-β pathway critically involved branching morphogenesis. Here, we characterize expression of miR200b at different gestational times using rat model CDH. Fetal rats deficient...

10.1016/j.omtn.2023.04.018 article EN cc-by-nc-nd Molecular Therapy — Nucleic Acids 2023-04-23

In utero gene editing has the potential to modify disease causing genes in multiple developing tissues before birth, possibly allowing for normal organ development, improvement, and conceivably, cure. cystic fibrosis (CF), a that arises from mutations transmembrane conductance regulator (

10.1101/2024.09.04.611031 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-09-08

Background Sexual harassment is a known problem in surgical training and focus of growing attention recent years. However, the environments where sexual most commonly takes place are not yet described. Methods An anonymous, voluntary, electronic survey was distributed to trainees, all programs nationally were invited participate. Results Sixteen general surgery elected participate, achieved response rate 30%. 48.9% respondents reported experiencing harassment. The common location for...

10.1177/00031348231189832 article EN The American Surgeon 2023-07-25

Rare cases of pancreatic neuroendocrine tumors (PNETs) that produce only proinsulin (PI) and manifest with hypoglycemia have been reported. Proinsulin expression in PNET has not systematically studied, the clinicopathologic features such remain unknown.We studied PI by immunohistochemistry (IHC) 136 PNETs from 2 high-volume surgical oncology centers assessed all available data.Thirty-six (26%) were positive for IHC, most (89%) which coexpressed insulin IHC. Nine PI-positive represented...

10.1097/mpa.0000000000001196 article EN Pancreas 2018-11-19

Background In academic hospitals, surgical residents write most of the postoperative prescriptions; yet, few are trained on analgesia. This leads to wide variability in practices and often excess opioid prescribing. We sought create an guideline pocket card for access when prescribing opioids postoperatively evaluate impact this initiative. Methods A comprehensive literature review was conducted generate evidence-based procedure-specific recommendations; additional recommendations were...

10.1177/0003134820940627 article EN The American Surgeon 2020-11-11

To study the relationship between carcinoembryonic antigen (CEA) level, intraductal papillary mucinous neoplasm (IPMN) subtype, and presence of invasive carcinoma.Cystic CEA level following pathologic variables: subtypes IPMN, size cystic lesion, dysplasia or carcinoma, main branch duct involvement from 45 IPMN cases were analyzed.There was a significant correlation pre-operative fluid intensity luminal staining. However, there no secretions epithelial cytoplasm staining, mucin glycoprotein...

10.14740/gr1201 article EN Gastroenterology Research 2019-01-01

Background Advances in Molecular Therapy have made gene editing through systemic or topical administration of reagents a feasible strategy to treat genetic diseases rational manner. Encapsulation therapeutic agents nanoparticles can improve intracellular delivery agents, provided that the are efficiently taken up within target cells. In prior work we had established proof-of-principle carrying mediate site-specific fetal and adult animals vivo results functional disease improvement rodent...

10.1371/journal.pone.0266218 article EN cc-by PLoS ONE 2022-04-06
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