- Maternal Mental Health During Pregnancy and Postpartum
- Breastfeeding Practices and Influences
- Child Nutrition and Feeding Issues
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- Statistical Methods and Inference
- Hepatitis B Virus Studies
- Advanced Causal Inference Techniques
- Ferroptosis and cancer prognosis
- COVID-19 Impact on Reproduction
- Liver Disease and Transplantation
- RNA modifications and cancer
- Domain Adaptation and Few-Shot Learning
- Sepsis Diagnosis and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Testicular diseases and treatments
- Neonatal Health and Biochemistry
- RNA Research and Splicing
- Patient Satisfaction in Healthcare
- Gestational Diabetes Research and Management
- Healthcare Education and Workforce Issues
- Nausea and vomiting management
- COVID-19 and Mental Health
- Maternal and Perinatal Health Interventions
- Central Venous Catheters and Hemodialysis
Zhejiang University
2023-2024
Southern Medical University
2017-2024
Wuhan University
2021-2024
Sir Run Run Shaw Hospital
2023-2024
Wuhan Donghu University
2022-2024
Nanfang Hospital
2024
The First People's Hospital of Shunde
2017-2021
The aim of the present study is to construct a competitive endogenous RNA (ceRNA) regulatory network by using differentially expressed long noncoding RNAs (lncRNAs), microRNAs (miRNAs), and mRNAs in patients with hepatocellular carcinoma (HCC), prognostic model for predicting overall survival (OS) HCC patients. Differentially lncRNAs, miRNAs, were explored between tissues normal liver tissues. A was built OS receiver operating characteristic curves used evaluate performance model. There 455...
This study aimed to establish a nomogram for predicting the probability of testicular salvage after torsion in children.
Breast cancer patients encounter challenges managing acute and chronic symptoms during after treatment, leading to emotional fluctuations diminished quality of life. Health education aims improve knowledge life skills; however, its specific impact on breast patients' self-efficacy is unclear. To assess the effects health self-efficacy, depressive symptoms, anxiety, distress, in patients. Randomized controlled studies were systematically screened 7 databases from inception database May 1,...
Accumulated evidences have demonstrated that long non-coding RNAs (lncRNAs) are correlated with prognosis of patients hepatocellular carcinoma. The current study aimed to develop and validate a prognostic lncRNA signature improve the prediction overall survival in carcinoma patients.The cohort involved 348 expression information information. Through gene mining approach, established (named LncRNA risk score) for predicting built predictive nomogram based on ten predictors through Cox...
Abstract Objective To explore factors associated with depression and COVID‐19 related fear among pregnant women new mothers. Design A cross‐sectional survey was conducted in China from July 2020 to 2021. Sample total of 3027 mothers were recruited. Measurement Sociodemographic characteristics the perceptions pandemic collected. The Patient Health Questionnaire‐9 (PHQ‐9) Fear Scale used assess depressive level towards pandemic, respectively. Results Approximately 17.2% participants had (PHQ‐9...
Abstract Background The current study aimed to construct competing endogenous RNA (ceRNA) regulation network and develop two precision medicine predictive tools for colorectal cancer (CRC). Methods Differentially expressed (DE) analyses were performed between CRC tissues normal tissues. A ceRNA was constructed based on DElncRNAs, DEmiRNAs, DEmRNAs. Results Fifteen mRNAs (ENDOU, MFN2, FASLG, SHOC2, VEGFA, ZFPM2, HOXC6, KLK10, DDIT4, LPGAT1, BEX4, DENND5B, PHF20L1, HSP90B1, PSPC1) identified...
The COVID-19 pandemic has caused unprecedented disruptions around the world. Adding to existing stress surrounding pregnancy and childbirth, threat of infection social isolation policies may negatively impact pregnant women new mothers. Literature on effect fear during childbirth experience is limited. As continues affect global population, it important understand how impacted mothers' experiences worldwide inform perinatal care interventions.This multicountry study involving China Canada...
Colorectal cancer remains a serious public health problem due to the poor prognosis. In present study, we attempted develop and validate prognostic signature predict individual mortality risk in colorectal patients.The original study datasets were downloaded from The Cancer Genome Atlas database. finally included 424 patients with wholly gene expression information overall survival information.A nine-lncRNA was built through univariate multivariate Cox proportional regression model....
Abstract Background Hepatocellular carcinoma (HCC) is a serious threat to public health due its poor prognosis. The current study aimed develop and validate prognostic nomogram predict the overall survival of HCC patients. Methods model cohort consisted 24,991 mRNA expression data points from 348 least absolute shrinkage selection operator method (LASSO) Cox regression was used evaluate biomarkers for Results Using multivariate proportional analyses, (named Eight-mRNA nomogram) constructed...
The basis of individualized treatment should be mortality risk predictive information. present study aimed to develop an online individual tool for acute-on-chronic liver failure (ACLF) patients based on a random survival forest (RSF) algorithm.The current retrospectively enrolled ACLF from the Department Infectious Diseases First People's Hospital Foshan, Shunde Southern Medical University, and Jiangmen Central Hospital. Two hundred seventy-six consecutive were included in as model cohort...
The relationship between prior breastfeeding experience and the duration of exclusive is significant interest, but few studies have explored mechanisms underlying this relationship. purpose study to address two hypotheses: (a) that attitude self-efficacy mediate previous breastfeeding; (b) serial mediation functions in relationship.The data collection process was divided into stages. original stage included 394 women hospitalized after delivery who completed socio-demographic questionnaires...
Returning to work after childbirth is a common reason for women stop breastfeeding. This study aimed assess breastfeeding practices and support available employed in China, factors affecting duration.A cross-sectional survey of 1,243 full-time was conducted. Participants completed sociodemographic questionnaire the Workplace Breastfeeding Support Scale (WBSS). Multiple linear regression analysis used explore that are associated with breastfeeding.The mean exclusive duration any were 5.7 ±...
Background A low breastfeeding rate causes an increased health care burden and negative outcomes for individuals society. Coparenting is essential tactic encouraging when raising a child. The efficacy of the coparenting interventions in enhancing breastfeeding-related controversial. Objective This study aimed to examine effects on exclusive rates, duration, knowledge, parenting sense competence, relationships, depressive symptoms new couples at 1 6 months post partum, BMI infants 42 days...
The aim of this retrospective study was to establish a simple self-assessed scale for individual risk cirrhosis in patients with chronic hepatitis B. A total 1808 consecutive were enrolled and analyzed. According the results multivariate logistic regression analysis, nomogram calculated cirrhosis. area under receiver operating characteristic curves (AUROCs) compare diagnostic accuracy aspartate aminotransferase platelet ratio index (APRI), fibrosis based on four factors (FIB-4), S index....
Background & Aims: Linear ubiquitin chain assembly complex (LUBAC) has been reported to participate in cancer progression, but its role hepatocellular carcinoma (HCC) remains unknown. This study aimed investigate the functions and potential tumorigenic mechanisms of LUBAC components HBV-associated HCC. Methods: The expression ( RBCK1 , RNF31 Sharpin ) Met1-linked ubiquitination (M1-Ubi) their correlation with prognosis were detected. biological HCC investigated vitro vivo . regulation on...
Previous studies have investigated influencing factors of early discontinuation breastfeeding, but few developed an easy-to-use tool to identify risk breastfeeding cessation at 6 months after birth. This research team aimed develop and validate exclusive duration nomogram in Chinese mothers. A longitudinal cohort survey was conducted. Data were collected from 394 postpartum women three hospitals Hubei Province, China December 2017 2018. The LASSO regression model used screen for optimized...
Classical Domain Adaptation methods acquire transferability by regularizing the overall distributional discrepancies between features in source domain (labeled) and target (unlabeled). They often do not differentiate whether differences come from marginals or dependence structures. In many business financial applications, labeling function usually has different sensitivities to changes versus Measuring will be discriminative enough acquiring transferability. Without needed structural...
It's challenging for healthcare workers to detect neonatal hypoglycemia due its rapid progression and lack of aura symptoms. This may lead brain function impairment the newborn, placing a significant care burden on family creating an economic society. Tools early diagnosis are lacking. study aimed identify newborns at high risk developing by prediction model.Using retrospective design, pairs (470) women their in tertiary hospital from December 2021 September 2022 were included this study....