A5030610901- Gut microbiota and health
- Genomics and Phylogenetic Studies
- Microbial Metabolites in Food Biotechnology
- Probiotics and Fermented Foods
- Dermatology and Skin Diseases
- Food composition and properties
- Pesticide Residue Analysis and Safety
- Bacterial biofilms and quorum sensing
- Liver Disease Diagnosis and Treatment
- Bioactive Natural Diterpenoids Research
- Phytochemistry and Biological Activities
- Digestive system and related health
- Plant and Fungal Interactions Research
- Microbial Natural Products and Biosynthesis
- Viral-associated cancers and disorders
- Hepatitis C virus research
- Aquaculture disease management and microbiota
- Pesticide Exposure and Toxicity
- Plant Reproductive Biology
- Synthetic Organic Chemistry Methods
- Hepatitis Viruses Studies and Epidemiology
- Healthcare and Venom Research
- Oral Health Pathology and Treatment
- COVID-19 Prevention and Impact
- Plant Molecular Biology Research
Keio University
2020-2025
University of Illinois Urbana-Champaign
2024
Southern Medical University
2024
Nanfang Hospital
2024
Keio University Shonan Fujisawa
2019-2024
Hohai University
2021
University of Tsukuba
2017
Zero to Three
2017
Institute of Crop Sciences
2015
Chinese Academy of Agricultural Sciences
2015
The coronavirus disease 2019 (COVID-19) pandemic has caused health issues worldwide. Studies have suggested that modulation of the gut microbiota could attenuate severity COVID-19 symptoms. In light this, we explored effects prebiotic dietary fibre partially hydrolyzed guar gum (PHGG) on SARS-CoV-2 infection in a Syrian hamster model, hypothesizing microbiome and intestinal metabolites through PHGG administration would improve outcomes. Eight hamsters each were assigned to control groups....
The human skin surface harbors huge numbers of microbes. microbiota interacts with its host and forms a microbiome profile that is specific for each individual. It has been reported the left on an individual's possessions can act as sort "fingerprint" be used owner identification. However, this approach needs to improved take into account any long-term instability contamination from nonspecific bacteria. Here, we took advantage single-nucleotide polymorphisms (SNPs) in 16S-encoding rRNA gene...
Abstract Current treatment options for COVID-19 are limited, with many antivirals and immunomodulators restricted to the most severe cases preventative care limited vaccination. As SARS-CoV-2 virus its increasing variants threaten become a permanent fixture of our lives, this new reality necessitates development cost-effective accessible COVID-19. Studies have shown that there correlations between gut microbiome severity COVID-19, especially regards production physiologically beneficial...
Optimal inflorescence architecture is important for plant reproductive success by affecting the ultimate number of flowers that set fruits and competitiveness when interacting with biotic or abiotic conditions. The pedicel one key contributors to diversity. To date, knowledge about molecular mechanisms development derived from Arabidopsis. Not much known regarding other plants. Here, an SVP family MADS-box gene, NtSVP, in tobacco (Nicotiana tabacum) required elongation was identified. It...
The coevolutionary dynamics of lytic viruses and microbes with CRISPR-Cas immunity exhibit alternations between sustained host control viral proliferation major epidemics in previous computational models. These alternating have yet to be observed other host–pathogen systems. Here, we address the breakdown transition large outbreaks a stochastic eco-evolutionary model. We establish role density-dependent competition punctuated virus-driven succession associated diversity trends that...
Many bacteria communicate with each other through signalling molecules, a process known as cell-to-cell communication. During this process, it is important for the molecules to: (1) reach target cells; and (2) to be received by cognate receptor. Barriers such presence of extracellular matrix may prevent signals from reaching their targets; however, influence on communication has scarcely been studied. Here, we demonstrate that overproduction an matrix, alginate, in Pseudomonas aeruginosa...
The gut microbiota is closely associated with human health and greatly impacted by the host diet. Bacteria such as Escherichia coli live in all throughout life of a adapt to intestinal environment. Adaptive mutations E. are reported enhance fitness mammalian intestine, but what extent still poorly known. It also unknown whether diet affects genes mutated affected. This study suggests that genetic K-12 strain selected response environment facilitate efficient utilization abundant nutrients...
Abstract The expression of herpesvirus genes during infection tissue culture cells can be classified into three main classes: immediate‐early (IE), early and late. transcriptional regulation IE is a critical regulatory step in the initiation viral infection, with their differing from that late genes. Herein, we report an gene (ORF3) promoter channel catfish virus (CCV, Ictalurid 1) activated regardless presence or absence CCV indicating ORF3 efficiently driven by host–cell transcription...
Adlercreutzia equolifaciens subsp. celatus DSM 18785 was isolated from the cecal contents of a rat and is an obligately anaerobic equol-producing bacterium. Here, we report finished annotated genome sequence this organism, which has size 2,929,991 bp G+C content 63.2%.
ABSTRACT Bulleidia sp. is a non-spore-forming, obligatory anaerobic, Gram-positive bacterium isolated from the stool samples of human colon cancer patients. We report complete genome sequence 10714-15, comprising single linear chromosome 2,218,984 bp with G + C content 36.6%.
Abstract Current treatment options for COVID-19 are limited, with many antivirals and immunomodulators restricted to the most severe cases preventative care limited vaccination. As SARS-CoV-2 virus its increasing variants threaten become a permanent fixture of our lives, this new reality necessitates development cost-effective accessible COVID-19. Studies have shown that there correlations between gut microbiome severity COVID-19, especially regards production physiologically beneficial...
Atopobiaceae sp. strain P1 ( Actinobacteria , Coriobacteriales ) was isolated from mouse feces. Here, we report the complete genome sequence of this strain, which has a total size 2,028,478 bp and G+C content 58.6%.
Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused worldwide health issues. Although several vaccines have been developed, it is still difficult to prevent and reduce the inflammation by infection. Studies shown that there are correlations between gut environment severity of symptoms SARS-CoV-2 Several metabolites produced microbiota such as SCFAs secondary bile acid UDCA reported improve survival rate host after viral infection in an animal model through modulation immune...
ABSTRACT Solobacterium moorei JCM 10645 T is an obligately anaerobic Gram-positive bacterium that was isolated from a human stool sample, generally known as associated with sepsis, bacteremia, halitosis, and periodontal disease. In this study, we report the complete genome sequence of strain, which 2.615 Mbp 37.2% GC content.