A5001848774- Analytical Chemistry and Chromatography
- Microfluidic and Capillary Electrophoresis Applications
- Analytical chemistry methods development
- Pesticide Residue Analysis and Safety
- Ginseng Biological Effects and Applications
- Mass Spectrometry Techniques and Applications
- Traditional Chinese Medicine Analysis
- Biopolymer Synthesis and Applications
- Electrochemical Analysis and Applications
- Nanopore and Nanochannel Transport Studies
- Pharmacological Effects of Natural Compounds
- Chemical Analysis and Environmental Impact
- Biosensors and Analytical Detection
- Quinazolinone synthesis and applications
- Hydrogels: synthesis, properties, applications
- Chromatography in Natural Products
- Agriculture, Soil, Plant Science
- Plant Toxicity and Pharmacological Properties
- Dye analysis and toxicity
- Phytochemistry and biological activity of medicinal plants
- Bioactive Compounds and Antitumor Agents
- Analytical Chemistry and Sensors
- Legionella and Acanthamoeba research
- Corporate Identity and Reputation
- Environmental Chemistry and Analysis
China Pharmaceutical University
2017-2024
Zhongkai University of Agriculture and Engineering
2021-2024
Harbin Engineering University
2016-2022
Shanghai University of Traditional Chinese Medicine
2019-2021
Jiangsu Provincial Center for Disease Control and Prevention
2005-2021
Jiangsu University of Science and Technology
2017
Sericultural Research Institute
2017
Chinese Academy of Agricultural Sciences
2017
Ministry of Education of the People's Republic of China
2017
Jilin University
2015-2016
Taking the improvement of cultivated land quality in Shaanxi Province as research object, main paths and safeguard measures to improve were discussed by analyzing current situation existing problems quality. The study found that is facing such soil degradation, fertility decline, increased pollution, which seriously restricts sustainable development agriculture. In view these problems, this paper puts forward some paths, improving structure, fertility, preventing pollution optimizing farming...
Abstract It was demonstrated that separation of DNA fragments by a CE‐contactless conductivity detection system (CE‐CCD) could be enhanced with multiple‐wall carbon nanotubes (MWCNs) as buffer additive. For Hae III digest ΦX174 DNA, optimized MWCN concentration obtained when the above its threshold concentration, at which form network in pseudostationary phase to provide additional interaction sites. In case larger near or below enough great improvement resolution, shown 2‐Log ladder....
2-amino-1-methyl-6-phenylimidazole [4, 5-b] pyridine (PhIP) is a prevalent heterocyclic amine (HAA) found in heated processed meat. This study investigated the inhibitory impact of eight different types polyphenols containing m-dihydroxyl structure on PhIP formation through chemical model system. The structure-activity relationship and potential sites action were also analyzed. Then, mechanism inhibiting by kaempferol, naringenin quercetin was speculated UPLC-MS. Results showed that 8 kinds...
Abstract This report describes a method to simultaneously determine 11 low‐molecular‐weight (LMW) organic acids and 16 chlorinated acid herbicides within single run by portable CE system with contactless conductivity detection (CCD) in poly(vinyl alcohol) (PVA)‐coated capillary. Under the optimized condition, LODs of CE‐CCD ranged from 0.056 0.270 ppm, which were better than for indirect UV (IUV) LMW or herbicides. Combined an on‐line field‐amplified sample stacking (FASS) procedure,...
The approach combines the advantages of a microwave and dynamic extraction technique, up to five soil samples can be treated.
Abstract Cation‐exchange micro solid‐phase extraction (SPE) tips and aqueous normal‐phase (ANP) chromatography coupled with tandem mass spectrometry were explored for the rapid, selective sensitive quantitation of desloratadine pseudoephedrine in human plasma. A novel micro‐SPE device was evaluated analyte capacity, efficiency its ability to maximize recovery an interest from bioanalytical matrices by successive replicates linked steps. Ion suppression using two different methods negligible...
PhIP (2-amino-1-methyl-6-phenylimidazole [4, 5-b] pyridine) is a carcinogenic heterocyclic aromatic amine often generated in thermal processing of food. Methods for and its precursors possible intermediates determination chemical model system roast pork were established based on HPLC-Q-Orbitrap-HRMS GC-MS. Results showed that the linearity 8 targets was good certain concentration range (R2 ≥ 0.992). LODs LOQs 0.3–15 μg/kg 1–50 μg/kg, respectively. Under system, recoveries target compounds...
Abstract A simple and rapid micellar electrokinetic chromatography (MEKC) method was developed for the separation determination of four toxic pyrrolizidine alkaloids (PAs) (senkirkine, senecionine, retrorsine, seneciphylline) in two traditional Chinese herbal medicines ( Qian liguang Kuan donghua ). Separation performed running buffer consisting 20 m M borate, 30 SDS, 20% methanol at pH 9.1. With optimized conditions, PAs were separated 17 min by a single run. The calibration curves showed...
EMR-Lipid was firstly introduced for cleanup of cream disinfection sample extracts in the determination antibacterial drugs by LC-MS/MS.
A portable capillary electrophoresis (CE) system with a novel potential gradient detection (PGD) was utilized to separate DNA fragments. For the first time it demonstrated that separation of fragments in polymer solution could be detected by CE integrated PGD, limit (LOD) comparable CE-ultraviolet (UV) method. Effects buffer solution, sieving medium, and applied voltage were also investigated. The CE-PGD shows several advantages, such as simplicity, cost effectiveness, miniaturization.
This report describes a novel online field-amplified sample stacking (FASS) procedure to analyze 16 chlorinated acid herbicides. By using poly(vinyl alcohol) (PVA)-coated capillary reduce electroosmotic flow and introducing methanol-water plug before loading, the injection time could be very long without loss of separation efficiency. Under optimized condition, FASS provide great sensitivity enhancement (5000-10 000-fold) satisfactory reproducibility (relative standard deviations migration...
Ginsenosides Rh1 and Rg3, as the main bioactive components from Ginseng, are effective for prevention treatment of cardiovascular diseases. Sheng-Mai-San (SMS), a classical complex prescription traditional Chinese medicines, is composed Radix Ginseng Rubra, Fructus Schisandrae, Ophiopogonis. In this research, sensitive specific liquid chromatography-mass spectrometric method was developed validated stereoselective determination pharmacokinetic studies 20(R)- 20(S)-ginsenoside Rg3 epimers in...
ABSTRACT The online management and training of information for laboratories has rarely been discussed in the traditional education system design. However, it plays a vital role informatization automation electrical power laboratory. Using PHP: Hypertext Preprocessor (PHP), we have designed developed an environment targeted In this article, Model‐View‐Controller (MVC) architecture cooperative modules was provided, key steps developing such using PHP were described. A questionnaire survey...
Abstract Several chemical and biological studies have revealed R , S ‐goitrin as the main bioactive constituent of Isatis indigotica Fort., responsible for antiviral antiendotoxin activity; however, few pharmacokinetic been conducted. To comprehend kinetics promote its curative application, a rapid sensitive UHPLC–MS/MS method was developed. The selected reaction monitoring transitions were m / z 130.0 → 70.0 181.1 124.0 internal standard in positive‐ion mode. established achieved good...
A simple and rapid method based on multi-throughput dynamic microwave-assisted extraction coupled online with salting-out-assisted liquid–liquid was developed for the analysis of chlorpyrifos in soil. First, extracted acetonitrile aqueous (50%, v/v) under action microwave energy. Then obtained extract separated clearly easily into an phase assistance ammonium acetate. The containing concentrated determined by liquid chromatography–tandem mass spectrometry. effects parameters efficiency...
Fifteen soil samples can be treated simultaneously in 20 min with low cost and less solvent by the proposed method.
Ulcerative colitis (UC) is an idiopathic inflammatory bowel disease, and the range of current clinical treatments not ideal. We previously found that polysaccharide Atractylodes macrocephala Koidz (PAMK) beneficial in DSS-induced colitis, we aimed to investigate underlying mechanisms this study.