A5104086549- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Lupus Erythematosus Research
- Asthma and respiratory diseases
- Pulmonary Hypertension Research and Treatments
- Acute Kidney Injury Research
- Renal Diseases and Glomerulopathies
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Atherosclerosis and Cardiovascular Diseases
- Respiratory and Cough-Related Research
- Chronic Kidney Disease and Diabetes
- Noise Effects and Management
- Radiomics and Machine Learning in Medical Imaging
- Sarcoidosis and Beryllium Toxicity Research
- Medical Imaging and Pathology Studies
- Cystic Fibrosis Research Advances
- Erythropoietin and Anemia Treatment
- Mycobacterium research and diagnosis
- Dermatology and Skin Diseases
- Systemic Sclerosis and Related Diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- COVID-19 and Mental Health
- Allergic Rhinitis and Sensitization
Chang Gung Memorial Hospital
2020-2025
Chang Gung University
2022-2023
Linkou Chang Gung Memorial Hospital
2022
Memorial Hospital of South Bend
2020-2022
Background: Non-pharmaceutical interventions (NPIs) were widely used during the coronavirus disease 2019 (COVID-19) pandemic, however their impact on acute asthma exacerbations (AEs) is not well studied.Methods: We had retrospectively collected patients with AEs between and 2020 retrieved data from Chang Gung Research Database, including clinical manifestations, medications, pulmonary function, clinic emergency department visits hospitalizations.Results: A total of 39,108 adult enrolled,...
Treatment responsiveness to corticosteroids is excellent for cryptogenic organizing pneumonia (COP) and sarcoidosis, but suboptimal idiopathic pulmonary fibrosis (IPF)/usual interstitial (UIP). We hypothesise that the differential expression of IL-17 contributes variable corticosteroid sensitivity in different lung diseases.To determine associations among IL-17, glucocorticoid receptor-β treatment diseases.Immunohistochemical (IHC) staining was performed on formalin-fixed paraffin-embedded...
Urine-soluble CD163 (usCD163) is released from alternatively activated macrophages involved in the resolution of inflammation glomeruli and plays an important role glomerulonephritis. This study explored usCD163 patients with systemic lupus erythematosus (SLE).usCD163 concentrations were measured cross-sectionally 261 SLE Taiwan. Clinical laboratory data collected, disease activity scores calculated to assess correlation usCD163.SLE high levels tended be younger, a higher hospital admission...
Objectives: This study aimed to examine and compare the findings of nail enthesis ultrasonography in patients with psoriasis psoriatic arthritis. Methods: We identified 154 arthritis 35 who were treated at Chang Gung Memorial Hospital, Taiwan, between September 2018 January 2019. Results: There significant differences Nail Psoriasis Severity Index scores Glasgow Ultrasound Enthesitis Scoring System those B-mode revealed that onychopathic changes more common group. The group showed a higher...
Heart failure with reduced ejection fraction (HFrEF) can coexist chronic obstructive pulmonary disease (COPD), which complicates the clinical situation and worsens quality of life. The study used standard diagnostic criteria for detecting COPD in hospitalized HFrEF patients to survey influence other comorbidities medications on long-term outcomes + patients.We retrospectively recruited due a tertiary medical center examined followed up outcomes, including length hospital stay, mortality,...
Cardiorenal syndrome type I (CRS I) is defined as the development of acute kidney injury (AKI) following decompensated heart failure (ADHF). The clinical significance endothelial markers in ADHF-associated AKI has yet to be clarified. This study therefore investigated biological processes linking ADHF and with aim determining whether plasma activation are associated patients ADHF. prospectively recruited 125 consecutive admitted a coronary critical unit due Patients without were compared...
Background: Early-onset asthma (EOA) and late-onset (LOA) are two distinct phenotypes.Air pollution has been associated with an increase in poorer outcomes.The objective of this study was to examine the effects traffic-related air (TRAP) on outcomes EOA LOA patients.Methods: A cross-sectional conducted 675 patients (LOA: 415) recruited from a major medical center Taiwan.The land-use regression (LUR) model used estimate level exposure PM 10 , 2.5 NO 2 O 3 individual level.We investigated...
In the past, patients with pulmonary hypertension (PH) were advised to avoid exercise due concerns that it might strain cardiac function and exacerbate symptoms. However, recent evidence indicates structured programs can enhance outcomes improve health-related quality of life for these patients. Consequently, rehabilitation is now recommended in international guidelines as a key component PH management. This consensus statement, developed by experts from Taiwan Society Cardiology Pulmonary...
Abstract Objective: Cardiorenal syndrome type I (CRS I) is defined as the development of acute kidney injury (AKI) following decompensated heart failure (ADHF). Note that clinical significance endothelial markers in ADHF-associated AKI has yet to be clarified. This study investigated biological processes linking ADHF and determine whether plasma activation could serve predictors for patients with ADHF. Methods: The prospectively recruited 125 consecutive admitted a coronary critical unit due...
The information regarding bronchiectasis with RA (BROS) is limited in Asia. objective of this study was to investigate the clinical characteristics and outcomes BROS Taiwan. This multi-institute cohort included patients from January 2006 December 2017. clinical, functional microbiological data these were retrieved Chang Gung Research Database. Respiratory failure mortality primary outcomes. Severe exacerbation defined as bronchiectasis- related hospitalizations or emergency department...
Differences in the clinical phenotypes and outcomes of fungus-associated asthma remain unclear. We aimed to investigate presentation asthmatics with fungal sensitization and/or positive isolates.Clinical characteristics, pulmonary function, microbiological data, allergy test reports, emergency department (ED) visits hospitalizations were retrieved from Chang Gung Research Database between 2010 2018; largest electronic medical record-based database Taiwan. Follow-up care was provided each...
<sec> <title>BACKGROUND</title> Rheumatoid arthritis (RA) is distinguished by the presence of modified bone microarchitecture, also known as 'texture,' in periarticular regions. The radiographic detection such alterations RA can be challenging. </sec> <title>OBJECTIVE</title> To train and to validate a deep learning model quantitatively produce texture features di-rectly from radiography predict diagnosis early without human reading. Two kinds models were compared for diagnostic performance....
Abstract Background : Heart failure with reduced ejection fraction (HFrEF) can coexist chronic obstructive pulmonary disease (COPD), which complicates the clinical situation and worsens quality of life. The study used standard diagnostic criteria for detecting COPD in hospitalized HFrEF patients to determine impact other comorbidities medications on long-term outcomes + patients. Methods We retrospectively recruited due a tertiary medical center examined followed up outcomes, including...
Abstract Objectives Urine soluble CD163 (usCD163) is released from alternatively activated macrophages involved in the resolution of inflammation glomeruli, and plays an important role glomerulonephritis. This study explored usCD163 patients with systemic lupus erythematosus (SLE). Methods concentrations were measured cross-sectionally 261 SLE patients. Clinical laboratory data collected, disease activity scores calculated to assess correlation usCD163. Results high levels tended be younger,...
Abstract We report a patient with systemic sclerosis who was diagnosed advanced-stage mucinous adenocarcinoma of the lungs. The clinical presentation, imaging findings, pathological results, and molecular diagnoses are presented. A 64-year-old woman administered prednisolone hydroxychloroquine sulfate to control her disease. High-resolution computed tomography (HRCT) revealed an interstitial pattern in both lungs during annual imaging. Connective tissue disease-associated lung disease...