A5047717611- Cardiovascular Health and Risk Factors
- Cardiovascular Disease and Adiposity
- Health disparities and outcomes
- Cardiovascular Function and Risk Factors
- Health, Environment, Cognitive Aging
- Innovations in Medical Education
- Telomeres, Telomerase, and Senescence
- Homelessness and Social Issues
- Global Public Health Policies and Epidemiology
- Metabolomics and Mass Spectrometry Studies
- Cardiac Imaging and Diagnostics
- Arsenic contamination and mitigation
- Medical Education and Admissions
- Physical Activity and Health
- Education Discipline and Inequality
- Aortic Thrombus and Embolism
- Birth, Development, and Health
- Diversity and Career in Medicine
- Aortic Disease and Treatment Approaches
- Fluoride Effects and Removal
- Glutathione Transferases and Polymorphisms
- Behavioral Health and Interventions
- Sleep and related disorders
- Epigenetics and DNA Methylation
- Child Abuse and Trauma
Florida College
2018-2022
University of Florida
2018-2022
East Tennessee State University
2016-2020
Background: Epigenetic dysregulation has been proposed as a key mechanism for arsenic-related cardiovascular disease (CVD). We evaluated differentially methylated positions (DMPs) potential mediators on the association between arsenic and CVD. Methods: Blood DNA methylation was measured in 2321 participants (mean age 56.2, 58.6% women) of Strong Heart Study, prospective cohort American Indians. Urinary species were using high-performance liquid chromatography coupled to inductively plasma...
American Indian communities experience a high burden of coronary heart disease (CHD). Strategies are needed to identify individuals at risk and implement preventive interventions.To investigate the association blood DNA methylation (DNAm) with incident CHD using large number sites (cytosine-phosphate-guanine [CpG]) in single model.This prospective study, including discovery cohort (the Strong Heart Study [SHS]) 4 additional cohorts Women's Health Initiative [WHI], Framingham [FHS],...
<b>Objective.</b> To evaluate the extent to which Doctor of Pharmacy students’ personal finance perceptions, projected student loan indebtedness, and demographic characteristics predict postgraduation career intentions. <b>Methods.</b> Students at three pharmacy colleges completed a 31-item survey instrument that assessed self-efficacy beliefs, anticipated debt upon graduation, postgraduate intentions, practice setting characteristics. Logistic regression models were used examine predicted...
To examine the association of cardiovascular disease risk factors with and their cumulative effect on coronary artery calcium in hard-to-reach asymptomatic patients diabetes.A total 2563 community-dwelling subjects from Central Appalachia participated screening at a heart centre. Binary variable was used to indicate that either present or absent. Independent variables consisted demographic modifiable medical conditions. Descriptive statistics multinomial logistic regression analyses were...
1. Exposure to secondhand smoke in hospitality settings Ghana: Evidence of changes since implementation smoke-free legislation Arti Singh, Gabriel Okello, Sean Semple, Fiona Dobbie, Tarja Kinnunen, Kwabena Lartey, Divine Logo, Linda Bauld, Sampson Ankrah, Ann McNeill, Ellis Owusu-Dabo Tobacco Induced Diseases CrossRef
Background and aim: Epigenetic dysregulation has been proposed as a key mechanism for arsenic-related cardiovascular disease (CVD). We evaluated differentially methylated positions (DMPs) potential mediators on the association between arsenic CVD. Methods: Blood DNA methylation was measured in 2321 participants of Strong Heart Study (SHS), prospective cohort American Indians. identified DMPs that are In cross-species analysis, we compared those with differential liver following early life...
<b>Objective.</b> To examine the extent to which theory of planned behavior (TPB) constructs and demographic characteristics explain pharmacy students’ dispensing intentions in ethically or legally gray areas involving potential substance misuse abuse. <b>Methods.</b> Two cohorts third-year Doctor Pharmacy (PharmD) students (n=159) were provided with five written cases describing common “gray area” scenarios community practice medications devices for abuse (eg, long-term buprenorphine...
Pulmonary artery (PA) diameter may be altered in association with cardiovascular (CV) risk factors as noted aorta systemic hypertension. The flow of blood from the right ventricle to PA and all way capillary level depends on pulmonary vascular resistance a lesser extent compliance impedance PA, which are fundamental conduit for maintenance heart hemodynamics. Our objective is determine between CV main (MPA) diameter.The study population asymptomatic individuals no known diagnosis diseases...
Background: Hypertension (HTN) is one of the major risk factors for cardiovascular diseases (CVD) that afflicts one-third population in United States (US). This study examined association between multiple modifiable HTN a rural hard-to-reach population. Methods: During January 2011 and December 2012, 1629 community-dwelling asymptomatic individuals from central Appalachia participated screening subclinical atherosclerosis, during which participants were asked to report whether physician or...
Background: Biological aging assessed by both leukocyte telomere length (LTL) and DNA methylation (DNAm) has been associated with CVD its risk factors. Moreover, LTL is epigenetically regulated. We hypothesized that LTL-associated epigenetic changes are of in the community. Objective: To test whether loci incident CVD, independent standard factors multi-ethnic cohorts. Method: evaluated 3,628 participants complete DNAm data four prospective cohorts, including 1,531 American Indians from...
Background: Dyslipidemia is associated with and often precedes the onset of chronic kidney disease (CKD). However, standard lipid panels fail to describe full spectrum blood lipidome. A longitudinal profiling lipidome risk CKD still lacking in any racial/ethnic group, including American Indians, a population that suffered disproportionately high burden CKD. Objective: To identify novel lipids lipidomic signatures independent traditional factors. Methods: We included 1,910 Indians who...