Jacob M. Tsitsi

ORCID: 0000-0002-1417-1324
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About
Contact & Profiles
Research Areas
  • Infectious Diseases and Tuberculosis
  • Pericarditis and Cardiac Tamponade
  • Kawasaki Disease and Coronary Complications
  • Palliative Care and End-of-Life Issues
  • Tuberculosis Research and Epidemiology
  • Grief, Bereavement, and Mental Health
  • SARS-CoV-2 and COVID-19 Research
  • Actinomycetales infections and treatment
  • Healthcare Policy and Management
  • HIV/AIDS Impact and Responses
  • Cardiovascular Issues in Pregnancy
  • Vaccine Coverage and Hesitancy
  • Infective Endocarditis Diagnosis and Management
  • Myasthenia Gravis and Thymoma
  • Leprosy Research and Treatment
  • Family Support in Illness
  • Inflammasome and immune disorders
  • COVID-19 epidemiological studies
  • Family Caregiving in Mental Illness
  • Religion, Spirituality, and Psychology
  • COVID-19 Clinical Research Studies
  • Infectious Diseases and Mycology
  • Mycobacterium research and diagnosis
  • Child and Adolescent Health
  • Mechanical Circulatory Support Devices

Chris Hani Baragwanath Hospital
2012-2021

University of the Witwatersrand
2013-2021

Tuberculous pericarditis is associated with high morbidity and mortality even if antituberculosis therapy administered. We evaluated the effects of adjunctive glucocorticoid Mycobacterium indicus pranii immunotherapy in patients tuberculous pericarditis.Using a 2-by-2 factorial design, we randomly assigned 1400 adults definite or probable to either prednisolone placebo for 6 weeks M. placebo, administered five injections over course 3 months. Two thirds participants had concomitant human...

10.1056/nejmoa1407380 article EN New England Journal of Medicine 2014-09-02

The aim of this study was to add the descriptive data pertaining epidemiology, presentation, and clinical course multisystem inflammatory syndrome (MIS) temporally associated with coronavirus disease 2019 in adults adolescents from low- middle-income countries.Patients presenting adult wards (14 years older) three academic hospitals South Africa, who were diagnosed MIS between August 1, 2020 May 31, 2021, reviewed retrospectively. laboratory radiographic findings, are described.Eleven cases...

10.1016/j.ijid.2021.08.042 article EN cc-by-nc-nd International Journal of Infectious Diseases 2021-08-21

COVID-19 vaccination has been globally accepted as a critical public health response measure to prevent severe disease and death, alleviate strain on healthcare systems, onward transmission of SARS-CoV-2. The South African Department Health's plan vaccinate 1.25 million workers through the Sisonke Early Access Vaccine Rollout for Healthcare Workers presented both opportunities challenges in terms designing implementing mass roll-out resource-limited state sector. We present our experiences...

10.7196/samj.2021.v111i7.15712 article EN South African Medical Journal 2021-05-06

Since late April 2020, a syndrome now termed Multisystem Inflammatory Syndrome in Children (MIS-C) has been seen children and adolescents association with COVID-19 infection. The definition of MIS-C involves fever, organ dysfunction laboratory confirmation inflammation the context or epidemiological evidence SARS-CoV-2 infection patient under 21 years age. Notably, cases are being identified adults Adults (MIS-A). Few have reported sub-Saharan Africa. We report case young African male...

10.11604/pamj.2021.38.174.27910 article EN cc-by Pan African Medical Journal 2021-01-01

Background. The World Health Organization announced a strategy to eliminate childhood leprosy infections, visible deformities and discriminatory legislation against patients by 2020. However, challenges in achieving leprosy-free world preventing neurological sequelae still exist. HIV infection is challenge South Africa (SA). HIV-leprosy co-infection may result an increase the frequency of reactions without affecting spectrum leprosy. From 1921 1997, prevalence remained <1 patient per 10 000...

10.7196/samj.2021.v111i9.15583 article EN South African Medical Journal 2021-09-02
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