A5006410250- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- SARS-CoV-2 and COVID-19 Research
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- Nail Diseases and Treatments
- Antibiotic Resistance in Bacteria
- Kawasaki Disease and Coronary Complications
- Lymphadenopathy Diagnosis and Analysis
- Infectious Diseases and Mycology
- HIV Research and Treatment
- Parasites and Host Interactions
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Bacterial biofilms and quorum sensing
- SARS-CoV-2 detection and testing
- Herpesvirus Infections and Treatments
- Viral-associated cancers and disorders
- Parasitic infections in humans and animals
- Lymphoma Diagnosis and Treatment
- Amoebic Infections and Treatments
- Tuberculosis Research and Epidemiology
- Parvovirus B19 Infection Studies
- Cardiovascular Issues in Pregnancy
South African Medical Research Council
2024
University of the Witwatersrand
2015-2024
St George's, University of London
2024
Chris Hani Baragwanath Hospital
2015-2022
Klebsiella pneumoniae causes community- and healthcare-associated infections in children adults. Globally 2019, an estimated 1.27 million (95% Uncertainty Interval [UI]: 0.91-1.71) 4.95 UI: 3.62-6.57) deaths were attributed to associated with bacterial antimicrobial resistance (AMR), respectively. K. was the second leading pathogen AMR resistant bacteria. Furthermore, rise of both hospital-acquired is a concern for neonates infants who are at high risk invasive disease. There limited...
The Southern African Journal of HIV Medicine is focused on HIV/AIDS treatment, prevention and related topics relevant to clinical public health practice. purpose the journal disseminate original research results support high-level learning Medicine. It publishes articles, editorials, case reports/case series, reviews state-of-the-art practice correspondence.
Abstract From April to September 2020, we investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in a cohort of 396 healthcare workers (HCWs) from 5 departments at Chris Hani Baragwanath Hospital, South Africa. Overall, 34.6% HCWs had polymerase chain reaction–confirmed SARS-CoV-2 infection (132.1 [95% confidence interval, 111.8–156.2] per 1000 person-months); an additional 27 were identified by serology. the internal medicine department highest rate (61.7%)....
Background Lymphadenopathy is a common clinical presentation of disease in South Africa (SA), particularly the era Human Immunodeficiency Virus (HIV) and tuberculosis (TB) co-infection. Methods Data from 560 lymph node biopsy reports specimens patients older than 12 years at Chris Hani Baragwanath Academic Hospital (CHBAH) between 1 January 2010 31 December 2012 was extracted National Health Laboratory Service (NHLS), division Anatomical Pathology. Cytology fine needle aspirates (FNAs)...
The aim of this study was to add the descriptive data pertaining epidemiology, presentation, and clinical course multisystem inflammatory syndrome (MIS) temporally associated with coronavirus disease 2019 in adults adolescents from low- middle-income countries.Patients presenting adult wards (14 years older) three academic hospitals South Africa, who were diagnosed MIS between August 1, 2020 May 31, 2021, reviewed retrospectively. laboratory radiographic findings, are described.Eleven cases...
COVID-19 vaccination has been globally accepted as a critical public health response measure to prevent severe disease and death, alleviate strain on healthcare systems, onward transmission of SARS-CoV-2. The South African Department Health's plan vaccinate 1.25 million workers through the Sisonke Early Access Vaccine Rollout for Healthcare Workers presented both opportunities challenges in terms designing implementing mass roll-out resource-limited state sector. We present our experiences...
Since late April 2020, a syndrome now termed Multisystem Inflammatory Syndrome in Children (MIS-C) has been seen children and adolescents association with COVID-19 infection. The definition of MIS-C involves fever, organ dysfunction laboratory confirmation inflammation the context or epidemiological evidence SARS-CoV-2 infection patient under 21 years age. Notably, cases are being identified adults Adults (MIS-A). Few have reported sub-Saharan Africa. We report case young African male...
Disseminated
We describe a classic case of nasal rhinosporidiosis in woman who resided Johannesburg, South Africa, but originated from rural area Eastern Cape Province. confirmed histologic diagnosis using PCR testing and compared details with those records on 17 other cases Africa.
Background: Protease inhibitors (PIs) have been recommended as World Health Organization second-line antiretroviral therapy (ART) for low- to middle-income countries two decades. As dolutegravir-based regimens become widely available, the future role of PIs is uncertain.Objectives: To describe characteristics patients on PI-based ART (in first-line and regimens), double-boosted protease (DBPI) who received recycled nucleoside reverse transcriptase (NRTI) in at a tertiary level clinic.Method:...
Human immunodeficiency virus (HIV) infection increases the risk of by a host other opportunistic pathogens. The clinical presentations these co-infections in immunocompromised patients are often atypical; therefore diagnosis is delayed absence investigations such as tissue biopsy. Infection may involve sites that difficult to access for biopsy and, consequence, there limited diagnostic available analysis. histopathologist, aided ancillary tests, relied upon make timeous and accurate...
Hydatid disease in the South African setting remains an important differential diagnosis many appropriate clinical presentations, such as splenomegaly. Splenic hydatid pregnancy is a rare and complex to manage.In this case report we describe of isolated splenic HIV-positive woman presenting her third trimester pregnancy.A multidisciplinary team consisting specialists from high-risk maternity unit, hepatobiliary surgery infectious diseases planned management patient, which included...