Rispah Chomba
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Nail Diseases and Treatments
- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- Amoebic Infections and Treatments
- COVID-19 epidemiological studies
- Tuberculosis Research and Epidemiology
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 detection and testing
- Sepsis Diagnosis and Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Salmonella and Campylobacter epidemiology
- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Bacterial Infections and Vaccines
University of the Witwatersrand
2019-2025
National Health Laboratory Service
2022-2024
Helen Joseph Hospital
2022
Abstract Background We assessed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA shedding duration and magnitude among persons living with human immunodeficiency virus (HIV, PLHIV). Methods From May through December 2020, we conducted a prospective cohort study at 20 hospitals in South Africa. Adults hospitalized symptomatic disease 2019 (COVID-19) were enrolled followed every days nasopharyngeal/oropharyngeal (NP/OP) swabs until documentation of cessation SARS-CoV-2 (2...
Background: Carbapenem-resistant Enterobacterales (CRE) are associated with significant morbidity and mortality. colonisation is an important prerequisite for infection, its surveillance crucial to reduce spread. However, data from South Africa limited.Objectives: We aimed determine CRE prevalence, the incidence of subsequent infections risk factors each.Method: retrospectively reviewed hospital records 686 patients admitted a medical high-care ward at tertiary in Gauteng, Africa, between...
Providing country-specific estimates of case fatality and sequelae from bacterial meningitis (BM) is important to evaluate monitor progress toward the World Health Organization's roadmap "defeating by 2030".From 2016-2020, GERMS-SA conducted enhanced surveillance at 26 hospitals across South Africa. Episodes laboratory-confirmed BM due Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis were included. Risk factors for in-hospital death hospital discharge among survivors...
Abstract Background: Biomarkers like procalcitonin (PCT) are an important antimicrobial stewardship tool for critically ill patients. The purpose of our study was to compare a guided antibiotic algorithm standard treatment in surgical trauma patients admitted the intensive care unit (ICU).Methods: A prospective, two period cross-over conducted South Africa. In first period, 40 were recruited into control group and antibiotics discontinued as per care. second if PCT decreased by ≥ 80% from...
Abstract Nontyphoidal Salmonella species usually cause self-limiting gastroenteritis. Extra-intestinal manifestations can occur, and purulent pericarditis is an extremely rare manifestation. It potentially life-threatening, a high index of suspicion required to prevent morbidity mortality. We report case enterica serovar Enteritidis infection manifesting as life-threatening pericardial tamponade in woman living with advanced HIV. highlights manifestation invasive nontyphoidal the importance...