Rudzani Mashau
- Fungal Infections and Studies
- Neonatal and Maternal Infections
- Antifungal resistance and susceptibility
- Nail Diseases and Treatments
- Global Maternal and Child Health
- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Neonatal skin health care
- Child Nutrition and Water Access
- Sepsis Diagnosis and Treatment
National Health Laboratory Service
2022-2025
National Institute for Communicable Diseases
2023-2024
National Center for Communicable Diseases
2022
Few population-level estimates of invasive neonatal infections have been reported from sub-Saharan Africa. We estimated the national incidence risk, aetiology, and pathogen antimicrobial susceptibility for culture-confirmed bloodstream meningitis in South
Introduction Worldwide, neonatal mortality remains high accounting for 47% of childhood deaths in 2019 and including an estimated 500 000 from infections. While 42% global occur sub-Saharan Africa, there is limited understanding population-level burden aetiology infections outside tertiary-level institutions. Methods analysis We aim to implement the first surveillance bloodstream meningitis among neonates aged <28 days South Africa. Tier 1 will include national culture-confirmed at all...
Introduction Bacterial meningitis is a major cause of death, with an approximate case fatality rate 37% across all age groups in South Africa. This study aimed to describe the demographic and pathogen characteristics incident children aged <1 year Africa from 2014 through 2018, during period when Haemophilus influenzae type b vaccine pneumococcal conjugate vaccines (PCV) were both included expanded program on immunization (EPI). Methods We conducted cohort routine laboratory data National...
Introduction Cryptococcal meningitis is a common fungal opportunistic infection and leading cause of death among people with advanced HIV disease in sub-Saharan Africa. The WHO recommends cryptococcal antigen (CrAg) screening followed by pre-emptive therapy to prevent this population. In 2016, South Africa was the first country implement reflexive laboratory CrAg nationally. Antigen Screen-and-Treat National Evaluation Team (CAST-NET) aims evaluate effectiveness national programme optimise...