A5089528392- Urban Transport and Accessibility
- Tryptophan and brain disorders
- Land Use and Ecosystem Services
- Environmental Impact and Sustainability
- demographic modeling and climate adaptation
- Agriculture Sustainability and Environmental Impact
- Urban and Freight Transport Logistics
- Neuroscience and Neuropharmacology Research
- Transportation Planning and Optimization
- Economic and Environmental Valuation
- Global Health Care Issues
- Asphalt Pavement Performance Evaluation
- Alzheimer's disease research and treatments
- Asthma and respiratory diseases
- Rural development and sustainability
- Neurogenesis and neuroplasticity mechanisms
- Dementia and Cognitive Impairment Research
- Fiscal Policy and Economic Growth
- Sustainable Agricultural Systems Analysis
- Transcranial Magnetic Stimulation Studies
- Underground infrastructure and sustainability
- Advanced Neuroimaging Techniques and Applications
- Sustainability and Climate Change Governance
- Sexual function and dysfunction studies
- Intracerebral and Subarachnoid Hemorrhage Research
Huazhong University of Science and Technology
2019-2024
Tongji Hospital
2019-2024
Huazhong Agricultural University
2018-2024
Hebei Medical University
2024
Fourth Hospital of Hebei Medical University
2024
Weatherford College
2024
University of Leeds
2013-2022
First Affiliated Hospital of Anhui Medical University
2017
Anhui Medical University
2017
Glutamate mediated excitotoxicity, such as oxidative stress, neuroinflammation, synaptic loss and neuronal death, is ubiquitous in Alzheimer's disease (AD). Our previous study found that 15 Hz repetitive transcranial magnetic stimulation (rTMS) could reduce cortical excitability. The purpose of this was to explore the therapeutic effect higher frequency rTMS on 3xTg-AD model mice further mechanisms rTMS.
Neuronal loss has been identified in depression, but its mechanisms are not fully understood. Proteomic analyses provide a novel insight to explore the potential of such pathological alterations. In this study, mice were treated with chronic unpredictable mild stress (CUMS) for 2 months establish depression models. The hippocampus was analyzed proteomic patterns by mass spectrometry followed Gene Ontology (GO) and Kyoto Encyclopedia Genes Genomes (KEGG) pathway analyses. Behavioral tests...
Recently numerous studies have demonstrated that neuroinflammation plays a critical role in the pathogenesis of depression. Repetitive transcranial magnetic stimulation (rTMS) has been used to treat depression for years but its mechanism is not fully elucidated. The present study was designed investigate whether rTMS could alleviate neuroglia-associated neuro-inflammatory process mice models depression.Mice were treated with chronic unpredictable mild stress (CUMS) induce and received four...
High-frequency repetitive transcranial magnetic stimulation (HF-rTMS) is widely used to treat depression. However, the underlying mechanism has not been identified, and there uncertainty regarding optimal choice of stimulus parameters, especially frequency. Our previous study in mice demonstrated that 10-Hz HF-rTMS ameliorated depression by inducing expression Homer1a reducing excitability cortical pyramidal cells. The aims this were compare effects 15-Hz 25-Hz a model chronic unpredictable...
Abstract Grey matter (GM) alterations may contribute to cognitive decline in individuals with white hyperintensities (WMH) but no consensus has yet emerged. Here, we investigated cortical thickness and grey volume 23 WMH patients mild impairment (WMH-MCI), 43 without impairment, 55 healthy controls. Both groups showed GM atrophy the bilateral thalamus, fronto-insular cortices, several parietal-temporal regions, WMH-MCI group more extensive severe atrophy. The thalamus cortices was associated...
White matter hyperintensities (WMH) are common in older adults and associated with cognitive decline. However, little is known about the functional changes underlying decline WMH subjects.To investigate whole-brain connectivity (FC) underpinnings of subjects using univariate multivariate analyses.Twenty-three mild impairment (WMH-MCI), 43 no (WMH-nCI), 55 healthy controls underwent resting-state MRI scans. Whole-brain FC was calculated fine-grained human Brainnetome Atlas, followed by...
Background: The outbreak of coronavirus disease 2019 in Wuhan, Hubei Province, China has seriously affected people's mental health. We aimed to assess the psychological impact on health care workers and non-health three different epidemic areas identify independent risk factors. Methods: surveyed 1,020 480 other cities except Wuhan provinces Hubei. Results: Health had higher levels anxiety depression than (p < 0.05), but there was no such difference > 0.05). Compared with regions, more...
The expansion of rural construction land in China has led to ecological consequences under the context depopulation, despite government use controls. While previous studies have investigated local factors contributing land, semi-urbanisation urban immigrants distant from areas received less attention. To better understand connections between and areas, this study constructed a network/spatial lag N/X (N/SLX) model that incorporated network lagged term socio-economic traits semi-urbanised...
Background: The goal of anesthesia in patients with hypertrophic obstructive cardiomyopathy (HOCM) is to reduce the risk left ventricular outflow tract obstruction triggered by anesthetics. Remimazolam a newly developed anesthetic that has been reported have superior hemodynamic stability. There no reports on completion non-cardiac surgery remimazolam HOCM. Methods: Here we report case 49-year-old man diagnosed who underwent resection colon cancer and remifentanil anesthesia. A bolus 0.3...
The Cropland Supplement Policy (CSP) helps maintain the total area of cropland in China as urban areas expand, but can result environmental degradation more natural habitat are turned into cropland. Current and future impacts CSP explored under different land-use change scenarios by comparing differences ecosystem services value (ESV) at province level. Scenario-based simulation results suggest that Hubei province, cost 19.53 billion CNY period 2000 to 2015 would an additional 12.54 2030...