- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Dementia and Cognitive Impairment Research
- Transcranial Magnetic Stimulation Studies
- Vestibular and auditory disorders
- Prostate Cancer Diagnosis and Treatment
- Hearing, Cochlea, Tinnitus, Genetics
- Sleep and Wakefulness Research
- EEG and Brain-Computer Interfaces
- Advanced Neuroimaging Techniques and Applications
- Traditional Chinese Medicine Studies
- Memory Processes and Influences
- Aging and Gerontology Research
- Retinal Imaging and Analysis
- Myofascial pain diagnosis and treatment
- Face Recognition and Perception
- Diet and metabolism studies
- Psychosomatic Disorders and Their Treatments
- Cannabis and Cannabinoid Research
- Vagus Nerve Stimulation Research
- Menstrual Health and Disorders
- Alcohol Consumption and Health Effects
- Prenatal Substance Exposure Effects
- Substance Abuse Treatment and Outcomes
- Clusterin in disease pathology
Wenzhou Medical University
2023-2024
Jinzhou Kangning Hospital
2023-2024
Centre for Addiction and Mental Health
2021-2024
XinHua Hospital
2023
Shanghai Jiao Tong University
2023
Huazhong University of Science and Technology
2021
Tongji Hospital
2021
Nanjing Medical University
2018-2021
Tianjin First Center Hospital
2021
Tianjin Medical University
2021
Effects of a specially designed aerobic dance routine on mild cognitive impairment Yi Zhu,1,* Han Wu,2,* Ming Qi,3 Sheng Wang,4 Qin Zhang,1 Li Zhou,1 Shiyan Wang,5 Wei Wang,6 Ting Wu,6 Xiao,7 Siyu Yang,8 Hong Chen,9 Ling Zhang,4 Kathryn Chu Zhang,10 Jinhui Ma,11,12 Tong Wang1 1Rehabilitation Department, The First Affiliated Hospital Nanjing Medical University, Nanjing, Jiangsu, China; 2Rehabilitation Drum Tower Hospital, the School at 3Radiology 4Rehabilitation Suzhou Science and Technology...
Objective To investigate the associations between cognition, anxiety, depression, and residual dizziness after successful repositioning maneuvers in elderly with benign paroxysmal positional vertigo (BPPV). Methods We enrolled 40 patients BPPV our outpatient department. used Dizziness Handicap Inventory (DHI), Visual Analog Scale (VAS), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder Questionnaire-7 (GAD-7) to assess degree of dizziness, depression participants before...
Abstract Grey matter (GM) alterations may contribute to cognitive decline in individuals with white hyperintensities (WMH) but no consensus has yet emerged. Here, we investigated cortical thickness and grey volume 23 WMH patients mild impairment (WMH-MCI), 43 without impairment, 55 healthy controls. Both groups showed GM atrophy the bilateral thalamus, fronto-insular cortices, several parietal-temporal regions, WMH-MCI group more extensive severe atrophy. The thalamus cortices was associated...
Objective: Our aim was to determine the correlation between cognitive impairment and P300 event-related potential (ERP) in older adults with vertigo imbalance, which further provides a reference for clinical diagnosis patients’ rehabilitation. Methods: A total of 79 adult patients imbalance our outpatient department from January 2022 December were selected divided into mild group (n = 20), moderate 39), severe 20) according Dizziness Handicap Inventory (DHI). The auditory component...
Background: Substance use disorders (SUDs) are pressing global public health problems. Executive functions (EFs) prominently featured in mechanistic models of addiction. However, there remain significant gaps our understanding EFs SUDs, including the dimensional relationships to underlying neural circuits, molecular biomarkers, disorder heterogeneity, and functional ability. To improve outcomes for people with interdisciplinary clinical, preclinical services research is needed inform...
Theta-gamma coupling (TGC) is a neurophysiologic mechanism that supports working memory (WM). TGC associated with N-back performance, WM task. Similar to TGC, theta and alpha event-related synchronization (ERS) desynchronization (ERD) are also WM. Few studies have examined the longitudinal relationship between performance ERS, or ERD. This study aimed determine if changes in (primary aim), as well ERS ERD over 6 12 weeks. Participants included 62 individuals aged 60 older no neuropsychiatric...
The Botox-A impact on the expression of SNAP-25 protein in rat chronic sciatic nerve pain model was assessed and mechanism inhibitory neurotransmitter imbalance studied. A constriction injury (CCI) consisted 30 healthy male rats. rats were randomly divided into sham-operated group, CCI group BoNT/A intervention during 1, 7 14 days we conducted mechanical withdrawal threshold (MWT) test thermal latency (TWL) before after operation. After days, animals sacrificed. level, mRNA subunit NR2B...
Abstract Objective Alcohol withdrawal syndrome (AWS) is a complex condition associated with alcohol use disorder (AUD), characterized by significant variations in symptom severity among patients. The psychological and emotional symptoms accompanying AWS significantly contribute to distress relapse risk. Despite the importance of neural adaptation processes AWS, limited genetic investigations have been conducted. This study primarily focuses on exploring single interaction effects...
Normal aging is associated with the shift in motivational priorities from knowledge acquisition to emotion regulation. Current evidence indicates an age-related increase preferences for positive over negative stimuli true memory. In present study, using categorized pictures paradigm, we investigated whether older adults would exhibit a greater false memory versus lures, compared young adults. We also examined association of executive functioning recognition A total 27 and 26 studied...
Objective Alcohol use disorder (AUD) is the second most prevalent mental and might be related to depression. Major vault protein (MVP) a cytoplasmic vesicle transport. The present study aimed investigate interaction between genetic variant (MVP rs4788186) depression in adult male Han Chinese with AUD during withdrawal. Methods All participants ( N = 435) were diagnosed AUD. dependence level was measured using Michigan Alcoholism Screening Test, self-rating scale. Genomic DNA extracted from...
Objective To study the characteristics of lanugage areas in Chinese Mandarin-English bilinguals whose first language is Mandarin.Methods 12 healthy volunteers had their BOLD-fMRI scanning with 3 tasks Mandarin and English:semantic judgement,phonology judgement mophology judgement.The images were analyzed by SPM8 software.The lateral index calculated for each bilingual tasks.Results Most traditional activated or English when performed.The common activation include right postcentral...
Objective To assess the value of free-hand transperineal multiparametric magnetic resonance imaging/transrectal ultrasound(mpMRI/TRUS) fusion-guided targeted biopsy(TB) for diagnosis prostate cancer(PCa). Methods Patients with elevated PSA level and/or an abnormal DRE finding were recruited prospectively between January 2015 and September 2016. Patients classified to various scores from 2 5 according prebiopsy mpMRI PI-RADS. Based on mpMRI/TRUS fusion-guiding, a 2-cores TB each...
目的 采用功能磁共振成像(functional MRI, fMRI)技术考察Alzheimer病(AD)视觉注意缺陷的原因,并对其相应的神经解剖基础进行初步探讨.方法 13例临床诊断可能为AD的患者和13例年龄、性别与之相匹配的健康老年人参加了2种不同视觉搜索的实验测试(即联合特征搜索和子集搜索任务:其中的靶刺激均具有2个特征,但前者是通过特征捆绑策略,后者是通过项目分组形成子集来完成任务).同时采用Siemens Sonata 1.5 T成像系统, 采集其脑部fMRI数据,通过功能神经成像分析软件SPM 99 (statistical parametric mapping software, SPM)进行统计分析得到脑功能活动的图像.结果尽管2个研究组在完成不同搜索任务时的脑区大部分相互重叠,包括顶叶、额叶、颞枕交界区、原始视皮层和皮层下结构等脑区,但不同脑区的激活强度和范围明显不同,AD组主要表现为双侧顶叶和左侧额叶激活减少,并以子集搜索任务时的组间差异更显著.结论...
Objective To study the effects of nicotine on osteogenic activity osteoblasts in vitro and factor vivo.Methods The were co-cultured with different concentrations ( 1 × 10-4 mol/L).The suppressive effect was examined by methyl thiazol tetrazolium (MTT) assay.The bone morphogenetic protein-2 (BMP-2)and alkaline phosphatase (ALP) tested enzyme linked immunosorbent assay (ELISA) mice.The osteopontin OPN),ALP,type collagen COL1 ) mRNA levels mouse femur detected reverse transcription-polymerase...
Objective To discuss the hematological adverse reactions of oral omeprazole administration with convention dosage and treatment course in aged patients.Methods Four hundred nine cases reflux esophagitis by endoscopic diagnosis from Beijing Hospital during January 2000 to December 2010 were divided into three groups according their ages: group A ( 168 cases) 60 69 years,group B 152 70 79 years C (89 equal or above 80 years.Each patients was randomly subgroups,A 1 56 cases),B 51 30 )...
You have accessJournal of UrologyInfections/Inflammation/Cystic Disease the Genitourinary Tract: Prostate & Genitalia II1 Apr 2017MP11-20 THE DIFFICULTY INTERPRETING ENDOTOXAEMIA POST TRANSRECTAL PROSTATE BIOPSY Peter Thompson, Wei Wang, Hemant Nemade, Srinath Chandersekara, Sharon Sheehan, Elias Khalifa, John Philpott - Howard, and Khalifa ThompsonPeter Thompson More articles by this author , WangWei Wang NemadeHemant Nemade ChandersekaraSrinath Chandersekara SheehanSharon Sheehan...