Cheng Chen

ORCID: 0000-0002-1423-118X
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About
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Research Areas
  • Photosynthetic Processes and Mechanisms
  • Light effects on plants
  • Photoreceptor and optogenetics research
  • Plant Stress Responses and Tolerance
  • Genomics and Phylogenetic Studies
  • Plant Molecular Biology Research
  • Plant biochemistry and biosynthesis
  • Autophagy in Disease and Therapy
  • Microbial Community Ecology and Physiology
  • Plant Reproductive Biology
  • Plant tissue culture and regeneration
  • Plant and Fungal Species Descriptions
  • Hops Chemistry and Applications
  • Enzyme Structure and Function
  • Peroxisome Proliferator-Activated Receptors
  • Connexins and lens biology
  • Protist diversity and phylogeny
  • Plant Diversity and Evolution
  • Skin and Cellular Biology Research
  • Ubiquitin and proteasome pathways
  • Plant Virus Research Studies
  • Oral Health Pathology and Treatment
  • Mitochondrial Function and Pathology
  • Advanced Glycation End Products research
  • Immune Response and Inflammation

Shanghai Jiao Tong University
2024-2025

Stomatology Hospital
2025

Xi'an Jiaotong University
2025

Michigan State University
2015-2021

University of Chinese Academy of Sciences
2014

Institute of Oceanology
2014

Chinese Academy of Sciences
2014

Yunnan Agricultural University
2013

Rice Research Institute
2013

Despite extensive research, the origin and evolution of chloroplast division machinery remain unclear. Here, we employ recently sequenced genomes transcriptomes Archaeplastida clades to identify core components reconstruct their evolutionary histories, respectively. Our findings show that complete ring structures emerged in Charophytes. We find Glaucophytes experienced strong selection pressure, generating diverse variants adapted changing terrestrial environments. By integrating functions...

10.1016/j.celrep.2024.113950 article EN cc-by Cell Reports 2024-03-01

INTRODUCTION Existing research suggests an association between smoking and the incidence of recurrent aphthous stomatitis (RAS); however, causal relationship remains ambiguous.We employed Mendelian randomization (MR) to clarify potential risk developing RAS.METHODS We utilized genome-wide study (GWAS) sequencing data related from Finnish database as instrumental variables (IVs) GWAS for RAS UK Biobank (UKB) outcome perform a two-sample MR analysis.The selection IVs was rigorously controlled...

10.18332/tid/199253 article EN cc-by Tobacco Induced Diseases 2025-01-15

Chloroplast division is driven by the simultaneous constriction of inner FtsZ ring (Z ring) and outer DRP5B ring. The assembly these rings in Arabidopsis (Arabidopsis thaliana) are coordinated partly through envelope membrane protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS6 (ARC6). Previously, we showed that PARC6 (PARALOG ARC6), also membrane, negatively regulates acts downstream ARC6 to position PLASTID DIVISION1 (PDV1), which functions together with its paralog PDV2 recruit...

10.1104/pp.15.01460 article EN PLANT PHYSIOLOGY 2015-11-02

The cytoskeletal Filamenting temperature-sensitive Z (FtsZ) ring is critical for cell division in bacteria and chloroplast photosynthetic eukaryotes. While bacterial FtsZ rings are composed of a single FtsZ, except the basal glaucophytes, involves two heteropolymer-forming isoforms: FtsZ1 FtsZ2 green lineage FtsZA FtsZB red algae. probably arose by duplication more ancestral FtsZA, respectively. We expressed fluorescent fusions from diverse organisms heterologous system to compare their...

10.1104/pp.17.00558 article EN PLANT PHYSIOLOGY 2017-08-16

Polyploidization promotes the functional diversification of autophagy in plants, expanding autophagy-associated genes (AAGs) to support processes like chloroplast division and flowering. Analysis 92,967 AAGs

10.1002/imt2.252 article EN cc-by iMeta 2024-12-01

Chloroplast division is initiated by assembly of the stromal Z ring, composed cytoskeletal Filamenting temperature-sensitive (FtsZ) proteins. Midplastid Z-ring positioning governed chloroplast Min (Minicell) system, which inhibits everywhere except site. The central Min-system player FtsZ-assembly inhibitor ACCUMULATION AND REPLICATION OF CHLOROPLASTS3 (ARC3). Here, we report Arabidopsis (Arabidopsis thaliana) chloroplasts contain two pools ARC3: one distributed throughout stroma, presumably...

10.1105/tpc.18.00948 article EN The Plant Cell 2019-03-01

Peroxisomes are dynamic organelles crucial for a variety of metabolic processes during the development eukaryotic organisms, and functionally linked to other subcellular organelles, such as mitochondria chloroplasts. Peroxisomal matrix proteins imported by peroxins (PEX proteins), yet modulation peroxin functions is poorly understood. We previously reported that, besides its known function in chloroplast protein import, Arabidopsis E3 ubiquitin ligase SP1 (suppressor ppi1 locus1) also...

10.1111/tpj.13900 article EN publisher-specific-oa The Plant Journal 2018-03-23

Chloroplast size varies considerably in nature, but the underlying mechanisms are unknown. By exploiting a near-isogenic line population derived from cross between Arabidopsis (Arabidopsis thaliana) accessions Cape Verde Islands (Cvi-1), which has larger chloroplasts, and Landsberg erecta (Ler-0), with smaller we determined that large-chloroplast phenotype Cvi-1 is associated allelic variation gene encoding chloroplast-division protein FtsZ2-2, tubulin-related cytoskeletal component of...

10.1104/pp.19.00841 article EN PLANT PHYSIOLOGY 2019-09-05

Bacterial cell and chloroplast division are driven by a contractile "Z ring" composed of the tubulin-like cytoskeletal GTPase FtsZ. Unlike bacterial Z rings, which consist single FtsZ, ring in plants is two FtsZ proteins, FtsZ1 FtsZ2. Both required for vivo, but their biochemical relationship poorly understood. We used assays, light scattering, transmission electron microscopy, sedimentation assays to investigate assembly behavior purified Arabidopsis thaliana (At) AtFtsZ2 both individually...

10.1016/j.jbc.2021.100627 article EN cc-by Journal of Biological Chemistry 2021-01-01

ABSTRACT Chloroplast division is initiated by the establishment of stromal FtsZ ring (Z ring). Assembly and positioning Z are governed chloroplast Min system, which inhibits Z-ring formation everywhere but middle chloroplast. ACCUMULATION AND REPLICATION OF CHLOROPLASTS3 (ARC3), core component this a direct inhibitor assembly. Regulation ARC3 activity vital thus for division. Here, we report that ARC6, localizes on inner envelope membrane, interacts with acts upstream during We show...

10.1101/2024.01.08.574726 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-01-08
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