A5033991085- Marine and coastal plant biology
- Algal biology and biofuel production
- Microbial Community Ecology and Physiology
- Seaweed-derived Bioactive Compounds
- Marine Bivalve and Aquaculture Studies
- Microbial Metabolic Engineering and Bioproduction
- Protist diversity and phylogeny
- Genomics and Phylogenetic Studies
- Lipid metabolism and biosynthesis
- Diatoms and Algae Research
- Polyamine Metabolism and Applications
- Plant Stress Responses and Tolerance
- Coastal wetland ecosystem dynamics
- Marine Biology and Ecology Research
- Probiotics and Fermented Foods
- Enzyme Catalysis and Immobilization
- Amino Acid Enzymes and Metabolism
- biodegradable polymer synthesis and properties
- Echinoderm biology and ecology
- Marine and coastal ecosystems
- Metabolomics and Mass Spectrometry Studies
- Coastal and Marine Management
- Water Quality Monitoring and Analysis
- Biopolymer Synthesis and Applications
- Polar Research and Ecology
University of York
2004-2025
Centre National de la Recherche Scientifique
2011-2021
Laboratoire de Biologie Intégrative des Modèles Marins
2014-2021
Station Biologique de Roscoff
2011-2021
Sorbonne Université
2011-2021
Université Paris Cité
2012-2015
Laboratoire des Biomolécules
2008-2012
Centre de Gestion Scientifique
2012
Centre de recherche Translationnelle en Médecine moléculaire
2010
Institut National de la Recherche Agronomique
2000-2001
The genome of Ectocarpus, a model organism for brown algae, has been sequenced. Brown algae are complex photosynthetic organisms that have adapted to life in rocky coastal environments. Genome analysis sheds light on this adaptation and reveals an extended set light-harvesting pigment biosynthesis genes novel metabolic processes such as halide metabolism. Comparative genomic analyses highlight the likely importance family receptor kinases related molecules evolution multicellularity plants,...
Seagrasses colonized the sea on at least three independent occasions to form basis of one most productive and widespread coastal ecosystems planet. Here we report genome Zostera marina (L.), first, our knowledge, marine angiosperm be fully sequenced. This reveals unique insights into genomic losses gains involved in achieving structural physiological adaptations required for its lifestyle, arguably severe habitat shift ever accomplished by flowering plants. Key innovations that were lost...
• Brown algal cell walls share some components with plants (cellulose) and animals (sulfated fucans), but they also contain unique polysaccharides (alginates). Analysis of the Ectocarpus genome provides a opportunity to decipher molecular bases these crucial metabolisms. An extensive bioinformatic census enzymes potentially involved in biogenesis remodeling cellulose, alginate fucans was performed, completed by phylogenetic analyses key enzymes. The routes for biosynthesis alginates sulfated...
Red seaweeds are key components of coastal ecosystems and economically important as food a source gelling agents, but their genes genomes have received little attention. Here we report the sequencing 105-Mbp genome florideophyte Chondrus crispus (Irish moss) annotation 9,606 genes. The features an unusual structure characterized by gene-dense regions surrounded repeat-rich dominated transposable elements. Despite its fairly large size, this shows typical compact genomes, e.g., on average...
Brown algae are photosynthetic multicellular marine organisms evolutionarily distant from land plants, with a distinctive cell wall. They feature carbohydrates shared plants (cellulose), animals (fucose-containing sulfated polysaccharides, FCSPs) or bacteria (alginates). How these components organized into three-dimensional extracellular matrix (ECM) still remains unclear. Recent molecular analysis of the corresponding biosynthetic routes points toward complex evolutionary history that...
Summary Alginate constitutes a significant part of seaweed biomass and thus crucial nutrient for numerous marine heterotrophic bacteria. However, the mechanisms alginate assimilation remain largely unknown in microorganisms. We show here that genome flavobacterium Zobellia galactanivorans contains seven putative lyase genes, five them localized within two clusters comprising additional carbohydrate‐related genes. The transcription these genes alginolytic activity were strongly induced when...
• Brown algae exhibit a unique carbon (C) storage metabolism. The photoassimilate D-fructose 6-phosphate is not used to produce sucrose but converted into D-mannitol. These seaweeds also store C as β-1,3-glucan (laminarin), thus markedly departing from most living organisms, which use α-1,4-glucans (glycogen or starch). Using combination of bioinformatic and phylogenetic approaches, we identified the candidate genes for enzymes involved in genome brown alga Ectocarpus siliculosus traced...
Brown algae (Phaeophyceae) are phylogenetically distant from red and green an important component of the coastal ecosystem. They have developed unique mechanisms that allow them to inhabit intertidal zone, environment with high levels abiotic stress. Ectocarpus siliculosus is being established as a genetic genomic model for brown algal lineage, but little known about its response Here we examine transcriptomic changes occur during short-term acclimation E. three different stress conditions...
Brown algae are sessile macro-organisms of great ecological relevance in coastal ecosystems. They evolved independently from land plants and other multicellular lineages, therefore hold several original ontogenic metabolic features. Most brown grow along the zone where they face frequent environmental changes, including exposure to toxic levels heavy metals such as copper (Cu). We carried out large-scale transcriptomic metabolomic analyses decipher short-term acclimation algal model E....
Abstract Background Dinoflagellates are aquatic protists particularly widespread in the oceans worldwide. Some responsible for toxic blooms while others live symbiotic relationships, either as mutualistic symbionts corals or parasites infecting other and animals. harbor atypically large genomes (~ 3 to 250 Gb), with gene organization expression patterns very different from closely related apicomplexan parasites. Here we sequenced analyzed of two early-diverging co-occurring parasitic...
Pelagic Sargassum species have been known for centuries in the Sargasso Sea of North Atlantic Ocean. In 2011, a new area concentrating high biomass these brown algae started developing Tropical Since then, massive and recurrent influxes reported Caribbean off coast Western Africa. These events major negative impact on coastal ecosystems nearshore marine life, affect socio-economic sectors, including public health, living, tourism, fisheries, maritime transport. Despite recent advances...
SUMMARY Brown seaweeds are keystone species of coastal ecosystems, often forming extensive underwater forests, that under considerable threat from climate change. Despite their ecological and evolutionary importance, this phylogenetic group, which is very distantly related to animals land plants, still poorly characterised at the genome level. Here we analyse 60 new genomes include all major brown algal orders. Comparative analysis these indicated occurrence several events coinciding...
To better understand the toxicity and orchestration of antioxidant defenses marine brown algae in response to copper-induced stress, lipid peroxidation processes were investigated alga Laminaria digitata. The expression genes involved cell protection anti-oxidant responses monitored by semi-quantitative reverse transcriptase polymerase chain reaction products further characterized profiling oxylipin signatures using high-pressure liquid chromatography-mass spectrometry. Exposure copper...
Chlorophyll-binding proteins (CBPs) constitute a large family of with diverse functions in both light-harvesting and photoprotection. The evolution CBPs has been debated, especially respect to the origin LI818 subfamily, members which function non-photochemical quenching have found chlorophyll a/c-containing algae several organisms green lineage, but not red so far. recent publication Ectocarpus siliculosus genome represents an opportunity expand on previous work carried out CBPs. codes for...
ABSTRACT The model brown alga Ectocarpus siliculosus undergoes extensive transcriptomic changes in response to abiotic stress, many of them related primary metabolism and particularly amino acid biosynthesis degradation. In this study we seek improve our knowledge the mechanisms underlying stress tolerance alga, particular with regard compatible osmolytes, by examining effects these on metabolite concentrations. We performed metabolic profiling (urea, acids, sugars, polyols, organic fatty...
Brown algae are plant multi-cellular organisms occupying most of the world coasts and essential actors in constitution ecological niches at shoreline. Ectocarpus siliculosus is an emerging model for brown algal research. Its genome has been sequenced, several tools being developed to perform analyses different levels cell organization, including transcriptomic expression analyses. Several topics, physiological responses osmotic stress exposure contaminants solvents studied order better...
Abstract Ectocarpus siliculosus is a cosmopolitan brown alga with capacity to thrive in copper enriched environments. Analysis of toxicity was conducted two strains E. isolated from (i) an uncontaminated coast southern Peru (Es32) and (ii) polluted rocky beach northern Chile (Es524). Es32 more sensitive than Es524, detected at 50 μg/L Cu, whereas Es524 displayed negative effects only when exposed 250 Cu. Differential soluble proteome profiling for each strain sub‐lethal levels allowed...
Increasing amounts of sequence data are becoming available for a wide range non-model organisms. Investigating and modelling the metabolic behaviour those organisms is highly relevant to understand their biology ecology. As sequences often incomplete poorly annotated, draft networks metabolism largely suffer from incompleteness. Appropriate gap-filling methods identify add missing reactions therefore required address this issue. However, current tools rely on phenotypic or taxonomic...
Brown algae belong to a phylogenetic lineage distantly related green plants and animals, are found predominantly in the intertidal zone, harsh frequently changing environment. Because of their unique evolutionary history habitat, brown feature several peculiarities metabolism. One these is mannitol cycle, which plays central role physiology, as acts carbon storage, osmoprotectant, antioxidant. This polyol derived directly from photoassimilate fructose-6-phosphate via action...
Cell walls of the brown algae contain a diverse range polysaccharides with useful bioactivities. The precise structures sulfated fucan/fucoidan group and their roles in generating cell wall architectures properties are not known detail. Four rat monoclonal antibodies, BAM1 to BAM4, directed fucan preparations, have been generated used dissect heterogeneity algal polysaccharides. respectively, bind non-sulfated epitope present preparations. BAM2 BAM3 identified additional distinct epitopes...