Éric Pelletier
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Protist diversity and phylogeny
- Environmental DNA in Biodiversity Studies
- Marine and coastal ecosystems
- Gut microbiota and health
- Bacteriophages and microbial interactions
- Marine Biology and Ecology Research
- Rheology and Fluid Dynamics Studies
- Methane Hydrates and Related Phenomena
- Wastewater Treatment and Nitrogen Removal
- Amino Acid Enzymes and Metabolism
- Chemical Reactions and Isotopes
- Clostridium difficile and Clostridium perfringens research
- Marine and environmental studies
- HIV Research and Treatment
- Marine and coastal plant biology
- Plant Virus Research Studies
- Identification and Quantification in Food
- Electrostatics and Colloid Interactions
- Hydrocarbon exploration and reservoir analysis
- Microbial Fuel Cells and Bioremediation
- Algorithms and Data Compression
- Epigenetics and DNA Methylation
- Marine Bivalve and Aquaculture Studies
Université Paris-Saclay
2005-2025
Centre National de la Recherche Scientifique
2015-2025
CEA Paris-Saclay
2018-2025
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2016-2025
Genoscope
2016-2025
McGill University Health Centre
2024-2025
Génomique Métabolique du Genoscope
2008-2024
Institut National de Recherche et de Sécurité
2018-2024
University of Calgary
2022
Université d'Évry Val-d'Essonne
2008-2019
To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. Here we describe Illumina-based metagenomic sequencing, assembly characterization 3.3 million non-redundant microbial genes, derived from 576.7 gigabases sequence, faecal samples 124 European individuals. The gene set, ∼150 times larger than complement, contains an overwhelming majority prevalent (more frequent) genes cohort probably includes a large proportion intestinal...
Summary The paradox of a host specificity the human faecal microbiota otherwise acknowledged as characterized by global functionalities conserved between humans led us to explore existence phylogenetic core. We investigated presence set bacterial molecular species that would be altogether dominant and prevalent within healthy humans. A total 10 456 non‐chimeric 16S rRNA sequences were obtained after cloning PCR‐amplified rDNA from 17 DNA samples. Using alignment or tetranucleotide...
Nitrospira are barely studied and mostly uncultured nitrite-oxidizing bacteria, which are, according to molecular data, among the most diverse widespread nitrifiers in natural ecosystems biological wastewater treatment. Here, environmental genomics was used reconstruct complete genome of “ Candidatus defluvii” from an activated sludge enrichment culture. On basis this first-deciphered experimental we show that Ca . N. defluvii differs dramatically other known nitrite oxidizers key enzyme...
The ocean is home to myriad small planktonic organisms that underpin the functioning of marine ecosystems. However, their spatial patterns diversity and underlying drivers remain poorly known, precluding projections responses global changes. Here we investigate latitudinal gradients predictors plankton across archaea, bacteria, eukaryotes, major virus clades using both molecular imaging data from Tara Oceans. We show a decline for most groups toward poles, mainly driven by decreasing...
Ocean microbial communities strongly influence the biogeochemistry, food webs, and climate of our planet. Despite recent advances in understanding their taxonomic genomic compositions, little is known about how transcriptomes vary globally. Here, we present a dataset 187 metatranscriptomes 370 metagenomes from 126 globally distributed sampling stations establish resource 47 million genes to study community-level across depth layers pole-to-pole. We examine gene expression changes community...
Many microorganisms live in anaerobic environments. Most of these have not yet been cultivated. Here, we present, from a metagenomic analysis an digester municipal wastewater treatment plant, reconstruction the complete genome bacterium belonging to WWE1 candidate division. In silico proteome indicated that this might derive most its carbon and energy fermentation amino acids, hence, it was provisionally classified as "Candidatus Cloacamonas acidaminovorans." acidaminovorans" is probably...
While our knowledge about the roles of microbes and viruses in ocean has increased tremendously due to recent advances genomics metagenomics, research on marine microbial eukaryotes zooplankton benefited much less from these new technologies because their larger genomes, enormous diversity, largely unexplored physiologies. Here, we use a metatranscriptomics approach capture expressed genes open Tara Oceans stations across four organismal size fractions. The individual sequence reads cluster...
Whereas DNA viruses are known to be abundant, diverse, and commonly key ecosystem players, RNA insufficiently studied outside disease settings. In this study, we analyzed ≈28 terabases of Global Ocean sequences expand Earth's virus catalogs their taxonomy, investigate evolutionary origins, assess marine biogeography from pole pole. Using new approaches optimize discovery classification, identified that necessitate substantive revisions taxonomy (doubling phyla adding >50% classes)...
Agulhas rings provide the principal route for ocean waters to circulate from Indo-Pacific Atlantic basin. Their influence on global circulation is well known, but their role in plankton transport largely unexplored. We show that, although coarse taxonomic structure of communities continuous across choke point, South diversity altered compared with Indian Ocean source populations. Modeling and situ sampling a young ring indicate that strong vertical mixing drives complex nitrogen cycling,...
Abstract A unique collection of oceanic samples was gathered by the Tara Oceans expeditions (2009–2013), targeting plankton organisms ranging from viruses to metazoans, and providing rich environmental context measurements. Thanks recent advances in field genomics, extensive sequencing has been performed for a deep genomic analysis this huge samples. strategy based on different approaches, such as metabarcoding, metagenomics, single-cell genomics metatranscriptomics, chosen size-fractionated...
Marine planktonic eukaryotes play critical roles in global biogeochemical cycles and climate. However, their poor representation culture collections limits our understanding of the evolutionary history genomic underpinnings ecosystems. Here, we used 280 billion
DNA viruses are increasingly recognized as influencing marine microbes and microbe-mediated biogeochemical cycling. However, little is known about global RNA virus diversity, ecology, ecosystem roles. In this study, we uncover patterns predictors of community- “species”-level diversity contextualize their ecological impacts from pole to pole. Our analyses revealed four zones, latitudinal depth patterns, environmental correlates for viruses. findings only partially parallel those cosampled...
DNA viruses have a major influence on the ecology and evolution of cellular organisms
Candida glabrata follows C. albicans as the second or third most prevalent cause of candidemia worldwide. These two pathogenic yeasts are distantly related, being part Nakaseomyces, a group more closely related to Saccharomyces cerevisiae. Although was thought be only new pathogens have recently been described within this group: nivariensis and bracarensis. To gain insight into genomic changes underlying emergence virulence, we sequenced genomes these two, three other non-pathogenic compared...