- Personality Disorders and Psychopathology
- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Functional Brain Connectivity Studies
- Psychosomatic Disorders and Their Treatments
- Autism Spectrum Disorder Research
- Mental Health and Psychiatry
- Treatment of Major Depression
- Psychotherapy Techniques and Applications
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Advanced Neuroimaging Techniques and Applications
- Suicide and Self-Harm Studies
- Geriatric Care and Nursing Homes
- Attention Deficit Hyperactivity Disorder
- Healthcare professionals’ stress and burnout
- Infant Health and Development
- Psychological Treatments and Disorders
- Respiratory Support and Mechanisms
- Intraoperative Neuromonitoring and Anesthetic Effects
- Personality Traits and Psychology
- Workplace Health and Well-being
- Diet and metabolism studies
- Child Abuse and Trauma
Azienda Ospedaliera di Desio e Vimercate
2024
Centro San Giovanni di Dio Fatebenefratelli
2014-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2014-2023
ORCID
2021
Westchester Medical Center
2021
McLean Hospital
2019-2021
Massachusetts General Hospital
2021
University of Milan
2013-2015
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2013-2015
Moriggia Pelascini Hospital
2013
Dose equivalence of antidepressants is critically important for clinical practice and research. There are several methods to define calculate dose but antidepressants, only daily defined consensus have been applied date. The purpose the present study examine by a less arbitrary more systematic method.We used data from all randomized, double-blind, flexible-dose trials comparing fluoxetine or paroxetine as standard drugs with any other active monotherapy in acute phase treatment unipolar...
Abstract Objective The validity of borderline personality disorder (BPD) in children and adolescents has not been studied a rigorous manner reflecting the criteria Robins Guze first detailed 1970. This paper others this series address some aspects multifaceted validation paradigm, which requires that known clinical presentation, can be delimited from other disorders, ‘runs’ families, something its aetiology, treatment response course is known. Methods Three groups subjects were studied: 104...
Abstract Objective Existing research has demonstrated that both adolescents and adults with borderline personality disorder (BPD) report higher rates of childhood adversity than their same‐age peers; no studies have examined if BPD differ based on the extent these experiences. In present study, we compared prevalence severity multiple forms abuse neglect in psychiatrically healthy adolescents. Methods Participants included 104 adolescent (aged 13–17 years) inpatients BPD, 60 age‐matched,...
Different psychotherapeutic approaches demonstrated their efficacy but the possible neurobiological mechanism underlying effect of psychotherapy in borderline personality disorder (BPD) patients is poorly investigated. We assessed effects metacognitive interpersonal therapy (MIT) on BPD features and other dimensions compared to structured clinical management (SCM). also changes amygdala activation by viewing emotional pictures after psychotherapy. One hundred forty-one were referred 78...
Borderline personality disorder (BPD) is a chronic condition with strong impact on patients' affective, cognitive and social functioning. Neuroimaging techniques offer invaluable tools to understand the biological substrate of disease. We aimed investigate gray matter alterations over whole cortex in group Personality Disorder patients compared healthy controls (HC).Magnetic resonance-based cortical pattern matching was used assess density (GMD) 26 BPD their age- sex-matched HC (age: 38 ±...
Abstract Objective Little is known about the psychosocial functioning of adolescents with borderline personality disorder (BPD). The main objective this paper to compare a group BPD psychiatrically healthy adolescents. Methods present cross‐sectional study included 104 adolescent inpatients BPD, compared 60 age‐matched comparison subjects. All participants were rigorously diagnosed using three semi‐structured interviews: Structured Clinical Interview for DSM‐IV Childhood Diagnoses, Revised...
The objective of this study was to assess the association between variables reflecting childhood adversity, protective experiences, and five-factor model personality BPD in adolescents. Two groups adolescents were studied: 104 met criteria for 60 psychiatrically healthy. Adverse experiences assessed using a semistructured interview. NEO-FFI. Eight nine indicating severity abuse neglect, positive relationships, competence, factors studied found be significant bivariate risk adolescent BPD....
Personality traits provide a description of individual emotional and cognitive processes that modulate thoughts, feelings behaviour. Few studies have investigated the relationship personality with depression anxiety in general Italian population. The aim present study was to replicate previous evidences about association population sample. We recruited 418 volunteers through different sources; such as university, newspaper advertisement, hospital, elderly association. 327 subjects accepted...
Abstract Objective Existing literature on the aetiology of borderline personality disorder (BPD) has primarily focused pathological childhood experiences, while little to no research been conducted protective factors that may serve ameliorate these symptoms. The current study attempts fill this gap in by comparing rates among adolescents with BPD, psychiatrically healthy and adults BPD. Methods One hundred four subjects were adolescent inpatients between ages 13 17 who met Revised Diagnostic...
Abstract Background Borderline personality disorder (BPD) is a psychiatric condition associated with the impairment of frontolimbic network. However, growing body studies suggests that brain dysfunction underling BPD could involve other areas. We explored whole‐brain white matter (WM) organization in patients to clarify structural pattern underlying disease and its relationship clinical features. Methods Fourteen 14 healthy controls underwent multidimensional assessment diffusion tensor...
Symptomatic disorders often co-occur with borderline personality disorder (BPD). This study's purpose was to compare the rates of comorbidity reported by adult and adolescent inpatients BPD, including complex (i.e., a combination affect impulsivity). One hundred four adolescents (aged 13-17) 290 adults 18-35) BPD were interviewed using an age-appropriate semistructured interview for assessment symptomatic disorders. Lifetime mood ADHD quite similar two study groups. However, anxiety...
This study evaluated levels and risk factors of burnout in a sample mental health professionals employed nonhospital psychiatric residential facilities northern Italy.Nurses, nurse assistants, educators completed questionnaire evaluating demographic variables, (Maslach Burnout Inventory), job characteristics (Job Diagnostic Survey), workload, relationships with colleagues, support from supervising coordinators. A total 202 (83% response rate) questionnaires were analyzed. Logistic linear...
Objective: To assess the effectiveness of a cognitive-behavioral therapy-based intervention (Superwellness Program) on weight gain compared with treatment-as-usual (TAU) approach in patients treated antipsychotics, and to evaluate relationship between body mass index (BMI) variation clinical variables. Method: Eighty-five antipsychotics were allocated across two groups, experimental (n=59) control (n=26). The Superwellness Program (experimental group) consisted 32 twice-weekly 1-hour...
Borderline Personality Disorder (BPD) is a complex and debilitating disorder, characterized by deficits in metacognition emotion dysregulation. The "gold standard" treatment for this disorder psychotherapy with pharmacotherapy as an adjunctive to target state symptoms. present randomized clinical trial aims assess the neurobiological changes following Metacognitive Interpersonal Therapy (MIT) compared Structured Clinical Management (SCM) derived from specific recommendations APA (American...
Prior research has demonstrated a link between childhood sexual abuse and borderline personality disorder (BPD) in adolescents adults indicated that more severe is related to poorer psychosocial functioning. The present study describes the overall severity of abuse/assault with BPD compares both groups on specific parameters abusive assaultive experiences.Participants included 104 adolescent (aged 13-17 years) inpatients 290 adult BPD. All participants completed two interviews assessed...
Cognitive remediation therapy (CRT) has been reported to positively affect neurocognitive processes among patients with schizophrenia; however, the degree which changes in cognition is linked improved clinical symptoms, remains poorly understood. The current study aimed investigate whether cognitive gains were associated improvements negative symptoms' severity schizophrenia living two Italian psychiatric facilities.Patients a diagnosis of consecutively assigned CRT (n = 33) and compared an...
Abstract Background Emotional dysregulation (ED) constitutes a relevant factor involved in the onset and maintenance of many mental disorders. Targeting ED during adolescence could be determinant both to identify high-risk individuals promote preventive interventions. This study will aim evaluate impact brief Dialectical Behavioral Therapy (DBT)-based intervention for adolescent students by measuring changes emotional regulation skills impulsive behaviors. Moreover, alterations biological...