Carlos Osorno‐Cruz

ORCID: 0000-0002-1490-7485
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About
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Research Areas
  • Intracranial Aneurysms: Treatment and Complications
  • Cerebrovascular and Carotid Artery Diseases
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Moyamoya disease diagnosis and treatment
  • Spinal Fractures and Fixation Techniques
  • Neurosurgical Procedures and Complications
  • Meningioma and schwannoma management
  • Vascular Malformations Diagnosis and Treatment
  • Aortic aneurysm repair treatments
  • S100 Proteins and Annexins
  • Cerebrospinal fluid and hydrocephalus
  • Cardiovascular Disease and Adiposity
  • Radiomics and Machine Learning in Medical Imaging
  • Head and Neck Surgical Oncology
  • Acute Ischemic Stroke Management
  • Vascular Procedures and Complications
  • Pituitary Gland Disorders and Treatments
  • MRI in cancer diagnosis
  • Traumatic Brain Injury and Neurovascular Disturbances

University of Iowa Hospitals and Clinics
2020-2022

Des Moines University
2022

University of Iowa
2020-2022

Stony Brook University
2020

Neurological Surgery
2020

Kanazawa University
2020

High-resolution vessel wall imaging (HR-VWI) has emerged as a valuable tool in assessing unruptured intracranial aneurysms (UIAs). There is no standardized method to quantify contrast enhancement of the aneurysm wall. Contrast can be objectively measured signal intensity (SI) or subjectively adjudicated. In this study, authors compared different methods UIAs and determined sensitivity specificity each surrogate instability. They also SI quantification between scanners from manufacturers.

10.3171/2019.12.jns192746 article EN Journal of neurosurgery 2020-02-08

INTRODUCTION: Woven Endobridge (WEB) is a safe and effective intrasaccular flow disruptor with over 80% adequate occlusion rates. However, complete rates remain around 50-60%. Recent studies showed that sizing modifications lateral compression correlate METHODS: This single center retrospective study of all cerebral aneurysms treated WEB devices from August 2015 to December 2023 follow-up data. We collected basic demographic, as well The aneurysm entry angle was calculated by measuring the...

10.1227/neu.0000000000003360_122 article EN Neurosurgery 2025-03-14

Background Aneurysm wall enhancement (AWE) is a potential surrogate biomarker for aneurysm instability. Previous studies have assessed AWE using 2D multiplanar methods, most of which were conducted qualitatively. Objective To use new quantitative tool to analyze large cohort saccular aneurysms with 3D-AWE maps Methods Saccular imaged prospectively 3T high resolution MRI. symptomatic (defined as ruptured or presentation sentinel headache/cranial nerve neuropathy) and asymptomatic created by...

10.1136/jnis-2022-019125 article EN Journal of NeuroInterventional Surgery 2022-07-19

Background: MR-quantitative susceptibility mapping (QSM) can identify microbleeds (MBs) in intracranial aneurysm (IA) wall associated with sentinel headache (SH) preceding subarachnoid hemorrhage. However, its use is limited, due to skull base bonny and air artifact. MR-vessel imaging (VWI) not limited by such artifact therefore could be an alternative QSM. The purpose of this study was investigate the correlation between QSM VWI detecting MBs help develop a diagnostic strategy for SH....

10.3390/jcm9040979 article EN Journal of Clinical Medicine 2020-04-01

There has not been any effective prophylaxis for delayed cerebral ischemia (DCI) since the introduction of nimodipine. Platelet inhibition may reduce risk by preventing formation microthrombi. Tirofiban used as a single monotherapy bridge given its safety profile and controlled platelet inhibition.To assess DCI in aneurysmal subarachnoid hemorrhages (aSAH) patients treated with tirofiban protocol.aSAH between December 2010 March 2019 who were stent assisted coiling or flow-diverting device...

10.1093/neuros/nyaa170 article EN Neurosurgery 2020-04-15

Biomechanical computational simulation of intracranial aneurysms has become a promising method for predicting features instability leading to aneurysm growth and rupture. Hemodynamic analysis behavior helped investigate the complex relationship between shape, morphology, flow patterns, proliferation or degradation wall. Finite element paired with high-resolution vessel wall imaging can provide more insight into how exactly morphology relates behavior, whether enhancement describe this...

10.3389/fneur.2021.764063 article EN cc-by Frontiers in Neurology 2021-12-10

Background: Anterior skull base meningiomas (ASBMs) account for about 10% of meningiomas. Bifrontal craniotomy (BFC) represents the traditional transcranial approach to accessing in these locations. Supraorbital (SOC) provides a minimally invasive subfrontal corridor select patients. Here, we present our series ASBM accessed by SOC and BFC single surgeon review decision-making compare outcomes both techniques. Methods: Thirty-three patients were identified with ASBM. Age, tumor...

10.25259/sni_767_2020 article EN cc-by-nc-sa Surgical Neurology International 2020-12-22

Background: High-resolution vessel wall imaging (HR-VWI) has emerged as a valuable tool in assessing unruptured intracranial aneurysms (UIAs). There is no standardized method to quantify contrast enhancement of the aneurysmal wall. Contrast reflected signal intensity (SI) at time objective quantification. This study compares all existing methods objectively UIAs. Methods: 3T HR-VWI was used prospectively image patients with Three different were analyzed T1 pre- and post-contrast sequences:...

10.1161/str.51.suppl_1.wmp29 article EN Stroke 2020-02-01

Objective: Imaging via MR-quantitative susceptibility mapping (QSM) can identify reliably microbleeds (MBs) associated with intracranial aneurysms (IAs) in subjects presenting severe headache suggestive of sentinel (SH) preceding subarachnoid hemorrhage. However, its use is limited due to skull base bonny artifact. Vessel wall imaging (VWI) not by artifact and therefore could be an alternative QSM detecting MBs. The purpose this study examine the correlation between MR-VWI MBs SH. Methods:...

10.1161/str.51.suppl_1.142 article EN Stroke 2020-02-01

Background: Aneurysm formation and growth might be explained by a local inflammatory/vasculopathic process that debilitates the wall of parent artery. Recently, presence aneurysm enhancement on high-resolution vessel imaging (HR-VWI) has been proposed as surrogate for inflammation. However, no studies have correlated circumferential (CAWE) aneurysm-to-pituitary ratio (CR stalk ) HR-VWI with (PVE) reference (RVE). Methods: Patients unruptured intracranial aneurysms prospectively underwent...

10.1161/str.51.suppl_1.143 article EN Stroke 2020-02-01

Introduction : Aneurysm wall enhancement using high‐resolution vessel imaging (HR‐VWI) may provide new surrogate biomarkers for instability. Finite element analysis (FEA) paired with HR‐VWI can more insight into complex morphological features that ultimately lead to aneurysm growth and rupture. Methods Unruptured intracranial aneurysms were reconstructed in 3D from CE‐MRA imaging. Shells created assuming a uniform thickness of 86 μm FEA was conducted 3rd order polynomial material model, the...

10.1161/svin.01.suppl_1.000213 article EN cc-by-nc-nd Stroke Vascular and Interventional Neurology 2021-11-01

Zanaty, Mario MD; Osorno-Cruz, Carlos BS; Byer, Stefano Roa, Jorge A Limaye, Kaustubh Ishii, Daizo Nakagawa, Daichi Torner, James PhD; Yongjun, Lu Ortega-Gutiérrez, Santiago MD, MSc; Samaniego, Edgar MS; Allan, Lauren DO; Hasan, David MD

10.1093/neuros/nyaa170_s036 article EN Neurosurgery 2021-11-18
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