- Genital Health and Disease
- Cerebral Palsy and Movement Disorders
- Female Genital Mutilation/Cutting Issues
- SARS-CoV-2 and COVID-19 Research
- Global Maternal and Child Health
- Adolescent Sexual and Reproductive Health
- Vaccine Coverage and Hesitancy
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- COVID-19 epidemiological studies
- Child Nutrition and Water Access
- COVID-19 Impact on Reproduction
- Parvovirus B19 Infection Studies
- Parasites and Host Interactions
- Urological Disorders and Treatments
- Neonatal and fetal brain pathology
- CNS Lymphoma Diagnosis and Treatment
- HIV, Drug Use, Sexual Risk
- Virology and Viral Diseases
- Pharmaceutical Economics and Policy
- Urologic and reproductive health conditions
- Viral Infections and Outbreaks Research
- Intimate Partner and Family Violence
- Reproductive tract infections research
- Child Nutrition and Feeding Issues
Makerere University
2000-2024
Uganda Virus Research Institute
2007
Rakai Health Sciences Program
2006
Background Male circumcision is associated with reduced HIV acquisition. Methods acquisition was determined in a cohort of 5507 HIV-negative Ugandan men, and 187 men discordant relationships. Transmission 223 HIV-positive partners. incidence per 100 person years (py) adjusted rate ratios (RR) 95% confidence intervals (CI) were estimated by Poisson regression. HIV-1 serum viral load for the seropositive partners HIV-discordant couples. Results The prevalence 16.5% all men; 99.1% Muslims 3.7%...
Objective: To examine the association between alcohol use and HIV acquisition. Design methods: We examined before sex incident in a population-based cohort Rakai, Uganda, 1994 2002. Adjusted incidence rate ratios (adjIRR) of acquisition 95% confidence intervals (CI) were estimated by Poisson multivariate regression. also adjusted prevalence to assess number partners consistency condom use. Results: In 6791 men 8084 women was 1.4 per 100 person-years 1.5 person-years, respectively. After...
BackgroundFew population-based studies of cerebral palsy have been done in low-income and middle-income countries. We aimed to examine prevalence subtypes, functional impairments, presumed time injury children Uganda.MethodsIn this study, we used a nested, three-stage, cross-sectional method (Iganga-Mayuge Health Demographic Surveillance System [HDSS]) screen for aged 2–17 years rural eastern Uganda district. A specialist team confirmed the diagnosis determined subtype, motor function...
Introduction: Male circumcision reduces HIV acquisition in men. We assessed whether foreskin surface area was associated with prior to circumcision. Methods: In two randomized trials of male circumcision, the measured after surgery using standardized procedures. Nine hundred and sixty-five initially HIV-negative men were enrolled a community cohort who subsequently trials, provided 3920.8 person-years observation estimated incidence per 100 categorized into quartiles. Results: Mean...
Burkitt's lymphoma (BL) is a major cause of death among Ugandan children. We studied clinical characteristics and outcomes childhood BL over time at the Uganda Cancer Institute (UCI). A total 1217 children (766 boys, 451 girls, mean age 6.69 years) diagnosed with between 1985 2005 were included. There no significant changes in proportion boys girls diagnosed, or diagnosis. Facial tumor (n = 945, 77.65%) abdominal disease 842, 69.19%) most common presentations. The presenting hepatic mass,...
Epstein-Barr virus (EBV) has been linked to malignancies and chronic inflammatory conditions. In this study, EBV detection was compared in children with non-Hodgkin's lymphoma conditions, using samples data from a case-control study carried out at the Mulago National Referral Hospital between 2004 2008. viral load measured saliva, whole blood white cells by real-time PCR. Serological values for IgG-VCA, EBNA1, EAd-IgG were conditions; Burkitt's other subtypes of lymphoma. Odds ratios (ORs)...
Abstract Background : In Uganda, a critical health concern emerges with Cerebral Palsy (CP), affecting approximately 2.7 per 1000 children. Notably, anecdotal evidence from rehabilitation centers suggests strong correlation between CP and the heightened risk of undernutrition its subsequent complications in children below five years. However, extent prevalence factors contributing to this condition among CP-afflicted Uganda’s remain largely unexplored. This study aimed ascertain identify...
The Phase III HIV vaccine trials are being planned, availability of information is limited on willingness to participate (WTP) among residents in some Ugandan urban areas.We determined the level and factors associated with Entebbe Municipality future trials, established their knowledge, beliefs attitude towards participation.A descriptive cross-sectional study was conducted aged 18-50 years.Two stage cluster sampling used obtain unit for quantitative aspect this while purposive done...
Background The measles Supplementary Immunization Activity (SIA) was implemented in June, 2017 to close immunity gaps by providing an additional opportunity vaccinate children aged between 9 months and up 14 years Lilongwe District, Malawi. This study conducted determine the proportion of eligible that were reached SIA among those with or without history vaccination, possible reasons for non-vaccination. Methods A cross-sectional survey using mixed methods conducted. Caretakers who sampled...
Halperin et al. [1] questioned whether behavioural confounding played a significant role in the protective effects of male circumcision on HIV acquisition and transmission our observational studies Rakai [2]. We attempted to conduct careful balanced epidemiological analysis assess potential efficacy prevention, after adjustment for differences religion behaviour among circumcised uncircumcised men Our data strongly suggest that is against acquisition, may also be male-to-female transmission....