A5100625064- Thyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Vitamin D Research Studies
- Growth Hormone and Insulin-like Growth Factors
- Blood disorders and treatments
- Neuroendocrine Tumor Research Advances
- Pituitary Gland Disorders and Treatments
- Immunodeficiency and Autoimmune Disorders
- Parathyroid Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Dietary Effects on Health
- Innovations in Medical Education
- Diet and metabolism studies
- S100 Proteins and Annexins
- Selenium in Biological Systems
- Glaucoma and retinal disorders
- Diabetes and associated disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pancreatitis Pathology and Treatment
- Erythrocyte Function and Pathophysiology
- Pancreatic function and diabetes
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Case Reports on Hematomas
- Pregnancy-related medical research
First Affiliated Hospital of Xi'an Jiaotong University
2015-2024
Xi'an Jiaotong University
2009-2024
Xi'an Medical University
2020
Peking University First Hospital
2014
Peking University
2012-2014
Beijing Jishuitan Hospital
2012
Harry Perkins Institute of Medical Research
2011
The University of Western Australia
2011
First Hospital of Xi'an
2007
Abstract Objective To assess the prevalence of diabetes and its risk factors. Design Population based, cross sectional study. Setting 31 provinces in mainland China with nationally representative data from 2015 to 2017. Participants 75 880 participants aged 18 older—a sample Chinese population. Main outcome measures Prevalence among adults living China, by sex, regions, ethnic groups, estimated 2018 American Diabetes Association (ADA) World Health Organization diagnostic criteria....
Background: Mandatory universal salt iodization (USI) has been implemented in China for 20 years. Although iodine deficiency disorders are effectively controlled, the risk of excess have debated. Methods: A nationally representative cross-sectional study with 78,470 enrolled participants, aged 18 years or older, from all 31 provincial regions mainland was performed. The participants were given a questionnaire and underwent B-mode ultrasonography thyroid. Serum concentrations thyroid...
The goal of eliminating iodine deficiency worldwide was successfully achieved in China after the implementation a mandatory universal salt iodization program for last 16 years. Thus, has been assessed as country with more than adequate levels. This survey aimed to investigate current status and effects an increased intake on spectrum prevalence thyroid disorders.A total 15,008 adult subjects from 10 cities eastern central were investigated. Serum thyrotropin (TSH), peroxidase antibodies...
Background: The fact that serum thyrotropin (TSH) levels increase with age may influence the diagnosis of thyroid diseases in older adults. This study aimed to establish an age-specific TSH reference range, examine prevalence adults ≥65 years, and analyze risk factors. Methods: A cross-sectional adult populations 10 cities China was conducted from 2010 2011. total 15,008 subjects were randomly selected completed present study. Urinary iodine concentration, TSH, peroxidase antibody (TPOAb),...
Background: Iodine is important in both thyroid function and human metabolism. Studies have explored the effect of iodine on metabolic disorders through function. This study aimed to investigate relationship between status disorders, such as syndrome (MetS), hypertension, impaired glucose metabolism, central obesity, dyslipidemia. Methods: A total 51,795 subjects aged ≥18 years from TIDE (Thyroid Disorders, Status Diabetes, a national epidemiological cross-sectional study) program were...
Hashimoto's thyroiditis (HT) is a common organ-specific autoimmune disease. Antithyroglobulin antibodies (TgAb) and antithyroperoxidase (TPOAb), predominantly of the immunoglobulin (Ig) G class, are hallmarks HT. It has been reported that HT can be divided into IgG4 non-IgG4 thyroiditis. The aim our study was to investigate meaning this classification.Thyroid sections from 53 patients with stored serum samples were collected detect IgG4, IgG, α-smooth muscle actin, transforming growth...
Background Hashimoto’s thyroiditis (HT) is the most prevalent inflammatory disorder of thyroid gland. Current studies have reported coexistence rate between HT and papillary carcinoma (PTC) quite high. The objective this study was to evaluate impact on predictive factors central compartment lymph node metastasis (CLNM) in PTC. Methods A retrospective investigation performed PTC patients. They were subclassified into non-HT groups. results preoperative neck ultrasound (US) examinations...
Although several studies have shown that cigarette smoking is associated with thyroid stimulating hormone (TSH), peroxidase antibody (TPOAb) and thyroglobulin (TgAb), the exact relationship between function controversial. As little known about effects of on TSH, TPOAb TgAb in Chinese residents. This study aimed to evaluate association ten-city residents China.This was a population-based cross-sectional study.In this study, 15,181 subjects from ten major cities China were investigated. Data...
Background: Iodine intake is associated with thyroid autoimmunity. In this study, we evaluated the changes in autoimmunity after 20 years of universal salt iodization (USI) China. Methods: A total 78,470 subjects (18 or older) from 31 provincial regions mainland China participated study. Serum peroxidase antibody (TPOAb), thyroglobulin (TgAb), TSH receptor antibody, thyrotropin (TSH), and urinary iodine concentration (UIC) were measured. Results: Positive TPOAb TgAb detected 10.19% [CI...
Background Universal salt iodization (USI) was implemented in mainland China 1996. The prevalence of hyperthyroidism and its risk factors now require examination. Methods Data were acquired from a nationwide Thyroid, Iodine, Diabetes Epidemiological survey (TIDE 2015–2017) 78,470 subjects 31 provinces. Iodine status, thyroid hormones antibodies measured. Results After two decades USI, the overt (OH), Graves’ disease (GD), severe subclinical (severe SCH), mild (mild SCH) 0.78%, 0.53%, 0.22%,...
Abstract This study aims to explore the patterns and associated factors of thyroid related disease comorbidity provide a novel insight for prevention management. After multi-stage stratified cluster random sampling, total 2272 participants were recruited, relevant data collected through door-to-door visits standardized questionnaire, anthropometric measurements biochemical examinations. Logistic regression analysis was utilized potential influences, least absolute shrinkage selection...
Background: Despite the implementation of universal salt iodization (USI) program for correction iodine deficiency in China ∼20 years, actual nutrition status Chinese residents and prevalence excess are issues that need to be addressed. This nationally representative cross-sectional study was conducted across all 31 provinces mainland gather extensive data on influential factors. Methods: included 78,470 participants, aged 18 years or older, who were interviewed asked answer a questionnaire....
Purpose: The expression of antibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) are very common in the sera patients with autoimmune diseases (AITD). relationship between auto-antibodies occurrence glucose lipid metabolic disorders remains unclear. This study was performed to investigate correlation presence serum TPOAb/TgAb those euthyroid general population. Methods: data this derived from Thyroid Disease, Iodine status Diabetes National epidemiological (TIDE) survey, a...
Background: Subclinical hypothyroidism is diagnosed based on serum thyrotropin (TSH) reference intervals, which in turn are affected by many factors. Methods: Data were acquired from a Chinese nationally representative cross-sectional study of 78,470 participants (TIDE study). The total population the TIDE program, and was subset defined National Academy Clinical Biochemistry (NACB) guidelines. Serum concentrations thyroid hormones, TSH, antibodies, urine iodine concentration (UIC) measured....
Antithyroid drug (ATD)-induced agranulocytosis is associated with human leukocyte antigen (HLA) and nearby genes in Southeast Asian European populations. The susceptibility of the Han population from northern China to ATD-induced has not been reported. We evaluated associations genetic variants at HLA-B HLA-DRB1 loci 32 candidate single nucleotide polymorphisms (SNPs) 29 patients 140 Graves' disease (GD) as controls. All subjects were descent China. HLA-B*27:05 (P = 1.10 × 10-4), HLA-B*38:02...
Abstract Background Hypothyroidism is a major manifestation of autoimmune thyroid diseases (AITD). We previously reported that low selenium (Se) status was linked to an elevated prevalence diseases. hypothesized Se may also influence the restoration function. Thus, this study aimed investigate factors affecting recovery function in patients with (sub-)clinical hypothyroidism, specific focus on status. Methods conducted 6-year prospective cohort comparing two counties different...
Background: Subclinical hypothyroidism (SCH) is the most common thyroid dysfunction, and its relationship with blood pressure (BP) has been controversial. The aim of study was to analyze association between SCH newly-diagnosed hypertension.Methods: Based on data from Thyroid disease, Iodine nutrition Diabetes Epidemiology (TIDE) study, 49,433 euthyroid individuals 7,719 patients aged ≥18 years were enrolled. Patients a history hypertension or disease excluded. determined by manufacturer...
Background. Associations between iodine intake and thyroid nodules (TNs) were not consistent. We aimed to illustrate the relationship urinary concentration (UIC) TNs. Methods. A total of 12,698 participants enrolled in analysis. All filled out questionnaires underwent physical examinations, laboratory tests, ultrasonography. UIC, serum thyrotropin (TSH), peroxidase antibodies (TPOAb), thyroglobulin (TgAb) measured central laboratory. Results. The prevalence TNs was 16.00%, median UIC 206.1...