A5006710672- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Microbial Fuel Cells and Bioremediation
- Conducting polymers and applications
- Electrocatalysts for Energy Conversion
- Molecular Sensors and Ion Detection
- Analytical Chemistry and Sensors
- Advanced biosensing and bioanalysis techniques
- Enzyme-mediated dye degradation
- Fuel Cells and Related Materials
- Bioactive Compounds and Antitumor Agents
- Biosensors and Analytical Detection
- Synthesis and Biological Evaluation
- Metal Extraction and Bioleaching
- Synthesis and Reactions of Organic Compounds
- Synthesis and biological activity
- Retinal Development and Disorders
- Synthesis and Characterization of Heterocyclic Compounds
- Supercapacitor Materials and Fabrication
- Synthesis of heterocyclic compounds
- Metal complexes synthesis and properties
- Neuroscience and Neural Engineering
- Oxidative Organic Chemistry Reactions
- Synthesis of Organic Compounds
- Photoreceptor and optogenetics research
Queen's University Belfast
2017-2024
Ollscoil na Gaillimhe – University of Galway
2010-2020
Belfast City Hospital
2017
University of Ulster
2017
National University of Ireland
2010
University of Manchester
1987
Growth of biofilms G. sulfurreducens on glassy carbon that yield a bioelectrocatalytic response to acetate oxidation is achieved using fixed applied potential, with current density for scaling potential. In contrast grown under electron acceptor-limiting conditions display redox signals shifted lower potentials and do not oxidise acetate.
Glucose oxidising enzyme electrodes have long been studied for their application to biosensors and, more recently, anodes in biofuel cells. At a fundamental level, insight into electron transfer and oxidation current generation at can be gained by systematic studies on integration of surfaces, biocatalysts, artificial substrates (mediators). In this perspective, we present an overview methods aid the development glucose based mediated continuous-use cell. Focus is placed rational design...
This review provides an overview of the current state-of-the-art and major trends in application protic ionic liquids (PILs) to sustainable chemistry.
A series of new heterodinuclear luminescent complexes with two different organic ligands have been synthesized and characterized. Ru(II)(polypyridine) moiety a metal-based anticancer fragment (AuCl, (p-cymene)RuCl2, (p-cymene)OsCl2, (Cp*)RhCl2, or Au-thioglucose) are the general features these complexes. All bimetallic compounds evaluated for their antiproliferative properties in vitro human cancer cell lines. Only containing an Au(I) exhibit activity range cisplatin higher. The...
Biofilms of the electroactive bacterium Geobacter sulfurreducens were induced to grow on graphite-rod electrodes under a potential 0 V (vs Ag/AgCl) in presence acetate as an electron donor. Increased anodic currents for bioelectrocatalytic oxidation obtained when incubated longer periods with periodic electron-donor feeding. The maximum current density increased 2.8-fold, and biofilm thickness by 4.25-fold, over time period 83-147 h. Cyclic voltammetry supports model heterogeneous transfer,...
The mechanism of inhibition water and glycerol permeation <italic>via</italic> human aquaglyceroporin-3 (AQP3) by gold(<sc>iii</sc>) complexes has been described, for the first time, using molecular dynamics (MD), combined with density functional theory (DFT) electrochemical studies.
Charge transport through<italic>Geobacter sulfurreducens</italic>biofilms increases with film thickness, as more porous films improves ion upon electrolysis.
Surface chemistry is known to influence the formation, composition, and electroactivity of electron-conducting biofilms. However, understanding evolution microbial composition during biofilm development its impact on electrochemical response limited. Here we present voltammetric, microscopic community analysis biofilms formed under fixed applied potential for modified graphite electrodes early (90 h) mature (340 growth phases. Electrodes introduce hydrophilic groups (-NH2, -COOH -OH) enhance...
The detection of nucleic acids based upon recognition surfaces formed by co-immobilization a redox polymer mediator and DNA probe sequences on gold electrodes is described. surface consists polymer, [Os(2,2'-bipyridine)2(polyvinylimidazole)10Cl]+/2+, model single strand cross-linked tethered to electrode via an anchoring self-assembled monolayer (SAM) cysteamine. Hybridization between the immobilized biotin-conjugated target sequence (designed from ssrA gene Listeria monocytogenes), followed...
Abstract We report on the performance of a prototype glucose/O 2 biofuel cell in physiological buffer. The consists cathode based Melanocarpus albomyces laccase (with reported T1 copper redox potential + 0.26 V vs. Ag/AgCl) co‐immobilised with an osmium polymer mediating film glassy carbon (GC) separated by Nafion 117 membrane from GC anode anolyte glucose oxidase, N , ′, ′‐tetramethyl‐ p ‐phenylenediamine (TMPD) as mediator, all immersed pH 7.4 phosphate buffer solution containing 0.15 M...
The key step in the synthesis of new five, six and seven-membered alicyclic ring [1,2-a]-fused bioreductive benzimidazolequinones was radical cyclisation. Six tributyltin hydride-mediated homolytic aromatic substitutions nucleophilic N-alkyl radicals onto benzimidazole-2-position occurred high yields (63-70 %) when quaternising pyridine-like 3-N imidazole with camphorsulfonic acid using large excesses azo-initiator, 1,1'-azobis(cyclohexanecarbonitrile), to supplement non-chain reaction....
Co-immobilisation approaches for preparation of glucose-oxidising films [Os(2,2′-bipyridine)2(poly-vinylimidazole)10Cl] and glucose oxidase on glassy carbon electrodes are compared. Electrodes prepared by crosslinking using glutaraldehyde vapour, without with a NaBH4 reduction, provide higher oxidation current than those well-established diepoxide method. Addition multi walled nanotubes to the film deposition solutions produces an enhanced density 5 mA cm−2 at 0.35 V vs. Ag/AgCl, whilst...
Abstract Co‐immobilisation of three separate multiple blue copper oxygenases, a Myceliophthora thermophila laccase, Streptomyces coelicolor laccase and Myrothecium verrucaria bilirubin oxidase, with an [Os(2,2′‐bipyridine) 2 (polyvinylimidazole) 10 Cl] +/2+ redox polymer in the presence multi‐walled carbon nanotubes (MWCNTs) on graphite electrodes results enzyme that produce current densities above 0.5 mA cm −2 for oxygen reduction at applied potential 0 V versus Ag/AgCl. Fully enzymatic...
Electron/proton transfers in water proceeding from ground/excited states are the elementary reactions of chemistry. These an iconic class molecules─polypyridineRu(II)─are now controlled by capturing or releasing three them with hosts that shape-switchable. Reversible erection collapse host walls allows such switchability. Some reaction rates suppressed factors up to 120 inclusive binding metal complexes. This puts nanometric coordination chemistry a box can be open shut as necessary. Such...
Layer-by-layer (LBL) assembly of alternate osmium redox polymers and glucose oxidase, at anode, laccase, cathode, using graphite electrodes form a membrane-less glucose/O(2) enzymatic fuel cell providing power density 103 μW cm(-2) pH 5.5.
Abstract Polymers containing TEMPO moieties are effective catalysts for the electrochemical oxidation of alcohols. Such polymers, almost exclusively, non‐commercial and prepared using multi‐step synthetic procedures. Here we show that a commercially available bearing polymer, Polyamine Immobilised Piperidinyl Oxyl (PIPO), is an homogeneous surface‐confined polymeric catalyst alcohol at carbonaceous electrodes. We probe electrolytic conditions stable electrocatalytic showing dichloromethane...