A5073430005- Antibiotic Use and Resistance
- Central Venous Catheters and Hemodialysis
- Bacterial Identification and Susceptibility Testing
- Urinary Tract Infections Management
- Patient Satisfaction in Healthcare
- Clostridium difficile and Clostridium perfringens research
- Patient Safety and Medication Errors
- Health Systems, Economic Evaluations, Quality of Life
- Sepsis Diagnosis and Treatment
- HIV Research and Treatment
- Infection Control and Ventilation
- Malaria Research and Control
- Clinical Reasoning and Diagnostic Skills
- Infection Control in Healthcare
- COVID-19 and Mental Health
- Vascular Procedures and Complications
- Syphilis Diagnosis and Treatment
- Healthcare Policy and Management
- HIV/AIDS Research and Interventions
- Healthcare cost, quality, practices
- Diverticular Disease and Complications
- Musculoskeletal Disorders and Rehabilitation
- Enterobacteriaceae and Cronobacter Research
- Healthcare Systems and Technology
- Autoimmune and Inflammatory Disorders Research
Columbia University Irving Medical Center
2024
Manhattan Institute for Policy Research
2023
University of Pittsburgh
2023
Lindsay Unified School District
2023
Oregon Medical Research Center
2023
Advisory Board Company (United States)
2023
New York Institute of Technology
2023
St. George's University
2023
Touro College
2023
New York City Health and Hospitals Corporation
2023
Abstract We observed bacterial or fungal coinfections in COVID-19 patients admitted between March 1 and April 18, 2020 (152 of 4,267, 3.6%). Among these patients, mortality was 57%; 74% were intubated; 51% with bacteremia had central venous catheters. Time to culture positivity 6–7 days, 79% received prior antibiotics. Metallo-β-lactamase–producing E. cloacae occurred 5 patients.
ABSTRACT Cerebral malaria (CM) is a major contributor to deaths, but its pathophysiology not well understood. While sequestration of parasitized erythrocytes thought be critical, the roles inflammation and coagulation are controversial. In large series Malawian children hospitalized with CM, HIV coinfection was more prevalent than in pediatric population estimates (15% versus 2%, P < 0.0001, chi-square test), higher mortality that seen HIV-uninfected (23% 17%, = 0.0178, test)....
A streamlined transition from inpatient to outpatient care can decrease 30-day readmissions. Outpatient parenteral antibiotic therapy (OPAT) programs have not reduced readmissions; an OPAT bundle has been suggested improve outcomes. We implemented a transition-of-care (TOC) and assessed the effects on all-cause, hospital readmission.Retrospectively, patients receiving postdischarge intravenous antibiotics were evaluated before after implementation of TOC-OPAT program in Bronx, New York,...
Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in respiratory cultures and diagnostic performance the MRSA nasal polymerase chain reaction (PCR) patients hospitalized with coronavirus disease 2019 (COVID-19) pneumonia - Volume 42 Issue 9
To impart principles of antimicrobial stewardship (AS) and infection prevention control (IPC), we developed a curriculum tailored to the diverse aptitudes learners at our medical center.We integrated case-based modules, group learning activities, smartphone applications (apps), decision support tools, prescription audit feedback into curricula school, medicine residency program, infectious diseases (ID) fellowship hospital program operations. Interventions were implemented in 2012-2016 using...
Severe sepsis and septic shock (SS/SS) treatment bundles reduce mortality, early infectious diseases (ID) consultation also improves patient outcomes. We retrospectively examined whether ID further outcomes in Emergency Department (ED) patients with SS/SS who complete the bundle.We included 248 adult ED completed 3-hour bundle. Patients within 12 hours of triage (n = 111; ID) were compared received standard care 137) for in-hospital 30-day readmission, length hospital stay (LOS), antibiotic...
BACKGROUND Hemophagocytic lymphohistiocytosis (HLH) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can trigger profound immune activation systemic inflammation, leading to severe, often fatal, conditions. Simultaneously, HIV-infected patients, prone dysregulation, face an increased risk of severe complications from SARS-CoV-2. The optimal timeline for initiating antiretroviral therapy (ART) in patients with SARS-CoV-2 HIV co-infection, especially concerning the HLH, remains...
Abstract Quality is central to value-based care, and measurement essential for assessing performance understanding improvement over time. Both care methods quality are evolving. Infectious diseases (ID) has been less engaged than other specialties in measure development, ID providers must seize the opportunity engage with development research. Antimicrobial stewardship programs an ideal starting point ID-related development; antimicrobial program interventions best practices specific,...
Only two cases of human infection with the anaerobic Gram-negative bacillus Butyricimonas virosa have been previously reported. We describe case a 69-year-old man B. and diverticulitis, further supporting an association bacteraemia this pathogen to bowel disease. also summarize characteristics described cases.
A 32-year-old nonlactational women with a nipple piercing and previous oral-to-breast contact presented findings consistent mastitis abscess, however, the patient failed multiple courses of empiric antimicrobials. Needle aspiration was performed culture positive for N. gonorrhoeae. She successfully treated intravenous ceftriaxone transitioned to oral ciprofloxacin once susceptibilities were known. gonorrhoeae is an uncommon cause abscess. few cases have been reported in context sexual...
Abstract Hospital-acquired infections remain a common cause of morbidity and mortality despite advances in infection prevention through use bundles, environmental cleaning, antimicrobial stewardship, other best practices. Current strategies further hospital-acquired reduction are limited by lack recognition the role that host–microbe interactions play susceptibility inability to analyze multiple risk factors real time accurately predict likelihood before it occurs inform medical decision...
Abstract Background: Peripherally inserted central catheters (PICCs) are increasingly used for vascular access in inpatient settings. Compared to multilumen PICCs, single-lumen PICCs carry a lower rate of complications, including central-line–associated bloodstream infection and thrombosis. Despite this, still overused. Methods: This quality improvement initiative was implemented across 11 hospitals at New York City Health + Hospitals safety net system. The electronic health record (EHR)...
Recent World Health Organization (WHO) guidelines recommend antiretroviral therapy (ART) for all HIV-infected people; previously CD4+ T lymphocyte quantification (CD4 count) or clinical staging determined eligibility children ≥ 5 years old in low- and middle-income countries. We examined positive predictive value (PPV) of a rapid diagnostic test (RDT) algorithm ART hospitalized with newly diagnosed HIV infection. enrolled 363 Malawian age 2 months to 16 two serial RDT from 2013 2015....
Most common reasons for consultation were pneumonia, sepsis, skin/soft tissue infections, and urinary tract infections. Building Bridges: Improving Antibiotic Prescribing in the Emergency Department Theresa Madaline, MD, Marta Feldmesser, FIDSA, Philip Chung, PharmD, MS, Johanna Daily, Mahalia Desruisseaux, Sarah Hochman, Marla Keller, Ira Leviton, Kerry Murphy, Anjali Sharma, Scott Pearlman, Nadine Katz, Deborah White, Liise-Anne Pirofski, FIDSA Belinda Ostrowsky, MPH, Albert Einstein...
Vol. 6, no. 5, doi:10.1128/mBio.01390-15, 2015. We correct the following errors in our published paper. These do not affect main findings showing significant intravascular accumulations of monocytes and platelets brain tissues children with fatal cerebral malaria (CM), which are more pronounced CM HIV coinfection than only CM. The numbers Fig. S1 summarizing overall Blantyre Malaria Project (BMP) …
185 students participated in the session; 75 completed an online survey. Survey comments revealed: Desire to incorporate IPC into curriculum Positive attitude toward active learning modalities such as donning and doffing of PPE handwashing 88% surveyed rated session on ‘Effective’ or ‘Very Effective’ achieving objectives. Many requested additional practice following areas prior beginning third year clerkships: Donning Hand Hygiene Safe disposal sharps The majority were able answer exam...
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In 2015, a transition-of-care outpatient parenteral antibiotic therapy service (TOC-OPAT) was established at the Montefiore Medical Center in Bronx, NY for patients requiring long-term antibiotics. Utilizing an OPAT bundle with direct communication between specialists, significant reductions 30-day readmissions were observed. is regional referral center orthopedic device-related infections (ODRIs). Here, we evaluate outcomes TOC-OPAT ORDIs. We hypothesize that majority achieve infection cure...
Abstract Background Severe sepsis and septic shock bundles have been shown to reduce mortality. Infectious Diseases (ID) consultation, particularly early in a hospital course, is associated with improved patient outcomes. Antibiotic Stewardship Program (ASP) decision support the ED has also clinical benefit. We aim examine addition of ID consultation existing ASP Emergency Department (ED) patients organ dysfunction and/or (SODS) who completed 3-hour bundle. Methods This retrospective study...
Background: Although central-line–associated bloodstream infections (CLABSI) in US hospitals have improved the last decade, ~30,100 CLABSIs occur annually. 1,2 Central venous catheters (CVC) carry a high risk of and should be limited to appropriate clinical indications. 6,7 Montefiore Medical Center, large, urban, academic medical center Bronx, serves high-risk population with multiple comobidities. 8–11 Despite this, critical care medicine (CCM) team is often consulted place CVC when...