Muhammad Ashraf
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Global Health and Surgery
- Global Health Workforce Issues
- Trauma and Emergency Care Studies
- COVID-19 and healthcare impacts
- Emergency and Acute Care Studies
- Global Maternal and Child Health
- Healthcare Systems and Challenges
- Hemoglobinopathies and Related Disorders
- Synthetic Organic Chemistry Methods
- Injury Epidemiology and Prevention
- Cancer Treatment and Pharmacology
- COVID-19 and Mental Health
- Sepsis Diagnosis and Treatment
- Global Health Care Issues
- COVID-19 diagnosis using AI
- Intensive Care Unit Cognitive Disorders
- Iron Metabolism and Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Mesoporous Materials and Catalysis
- Renal and related cancers
- Diversity and Career in Medicine
- Sperm and Testicular Function
- Respiratory Support and Mechanisms
Augusta University
2022-2023
Indus Hospital
2019-2023
Harvard University
2019-2022
Hospital Sungai Buloh
2022
Health Net
2019-2022
Directorate of Health
2022
Presbyterian Hospital
2019
Cornell University
2019
Aga Khan University Hospital
2016
International Center for Chemical and Biological Sciences
2002
Different neurological manifestations of coronavirus disease 2019 (COVID-19) in adults and children their impact have not been well characterized. We aimed to determine the prevalence in-hospital complications among hospitalized COVID-19 patients ascertain differences between children. conducted a prospective multicentre observational study using International Severe Acute Respiratory emerging Infection Consortium (ISARIC) cohort across 1507 sites worldwide from 30 January 2020 25 May 2021....
Abstract The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases prospectively collected clinical data on people hospitalized with COVID-19. This was compiled during pandemic by a network hospitals that collect using ISARIC-World Health Organization Clinical Characterization Protocol tools. database includes from more than 705,000 patients, in 60 countries 1,500 centres worldwide. Patient are...
The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) is a global federation of clinical research networks that work collaboratively to prevent illness deaths from infectious disease outbreaks. In 2014, we proposed effective timely during outbreaks emerging infections would benefit pre-prepared tools, collaboration, research-ready networks.1 After applying this model several outbreaks, particularly the COVID-19 pandemic, can now explore what has been achieved date.
Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining relationship between COVID-19 AKI low- low-middle income countries (LLMIC) are lacking. Given that is known to carry a higher mortality rate these countries, it important understand differences this population.
Research diversity and representativeness are paramount in building trust, generating valid biomedical knowledge, possibly implementing clinical guidelines.
Objective: To describe the initial experience and demographics of T2* cardiac magnetic resonance–based myocardial-iron quantification transfusion-dependent thalassemia-major (TM) patients from Pakistan correlation with serum ferritin. Methods: Eligible TM presenting between April 2014 2015 to Aga Khan University Hospital, Pakistan, for T2*CMR were included. The severity deposition was defined as follows: normal T2*>20 ms, mild-moderate T2*10 20 severe T2*<10 ms. Cardiac symptoms...
Very little is known about the state of surgical, anaesthesia and obstetric care in Pakistan.This study aimed to assess literature available on Pakistan understand strengths weaknesses this based domains framework national surgical plans, namely: infrastructure, workforce, service delivery, information management, governance delivery.Relevant studies English published between 2003 2018 were identified by searching electronic databases including PubMed/MEDLINE, EMBASE Scopus. Searches grey...
Two new rearranged taxane diterpenoids, 5α,7β,10β,13α-tetrahydroxy-2α,9α,15-triacetoxy-11(15→1)-abeo-taxa-4(20), 11-diene (1) and 5α,9α,10β,13α-tetraacetoxy-15-hydroxy-11(15→1)-abeo-taxa-4(20), (2) have been isolated from the barks of Taxus wallichiana. The structures these compounds confirmed by modern spectroscopic techniques.
<strong>Background:</strong> Pakistan is a lower middle-income country in South Asia with population of over 220 million. With the recent development national health programs focusing on surgical care, two areas high priority for research and policy are access financial risk protection related to surgery. This first study nationally assess geographic expenditures patients undergoing <strong>Methods:</strong> cross-sectional laparotomy, cesarean section, management fracture at public tertiary...
Pakistan is a lower middle-income country in South Asia with population of 225 million. No estimate for surgical care access exists the country. We postulate estimated to less than minimum 80% be achieved by 2030. conducted randomized, stratified two-stage cluster household survey. A sample 770 households was selected using 2017 census frames from Bureau Statistics. Data collected on choice hospital and travel time chosen C-section, laparotomy, open fracture repair (OFR), specialized...
To develop and propose a cost-effective trauma care network for Karachi, Pakistan, by calculating maximum timely (TTC) coverage achieved with the addition of potential designated private public level 1 2 centres (TCs).A lower middle-income country metropolis, Karachi is Pakistan's largest city population 16 million total 56 hospitals as per government registry data.41 TCs selected using two-level, contextually-relevant TC designation criteria adapted from various international...
Objective: To analyse the need of prophylactic antibiotic before insertion totally implantable venous access devices (TIVADs) in terms preventing central line-associated blood stream infection (CLABSI) early postoperative period pediatric oncology patients.Study Design: A cohort study.
Aims and Objectives: The study aims at investigating the complications associated with splenectomy in thalassemic patients Study Design: It was a prospective clinical study. Materials Method: Sixty Splenectomies were preformed electively after pre-operative preparation Sir Ganga Ram Hospital, Lahore during year Jan 2003 to Sep 2005. Results: Complications categorized into per-operative, early post-operative late complications. frequency of per-operative 3%, 10% 1.6%. Interpretation...
Research Objective Poor access and out‐of‐pocket expenses are barriers to equitable coverage of surgical care. We sought identify the logistical financial challenges faced by patients receiving care at public sector, tertiary hospitals in Pakistan. Study Design This is a cross‐sectional study. Patients who underwent Bellwether procedures (C‐section, laparotomy, fracture fixation) were interviewed. Data regarding their socioeconomic status, place residence, prehospital transport, cost...
Abstract For see ChemInform in Full Text.
Background: Wilms Tumour (WT) is one of the most curable childhood cancers. High cure rates seen in high-income countries are not duplicated low and middle-income due to several constraints. We reviewed our data over last 20 years order highlight some these challenges. Methods: This a retrospective review medical notes children with WT under age 18 presenting institution between 1 November 1997 30 2017. Demographic, presentation treatment details were recorded factors associated poor outcome...