Lovkesh Arora
A5030828901- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- COVID-19 and healthcare impacts
- Aortic Disease and Treatment Approaches
- Neuroscience of respiration and sleep
- Infective Endocarditis Diagnosis and Management
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Obstructive Sleep Apnea Research
- Airway Management and Intubation Techniques
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular and Diving-Related Complications
- Sepsis Diagnosis and Treatment
- Aortic aneurysm repair treatments
- Pleural and Pulmonary Diseases
- Spinal Hematomas and Complications
- COVID-19 and Mental Health
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Hemodynamic Monitoring and Therapy
University of Iowa
2019-2025
University of Iowa Hospitals and Clinics
2017-2024
Prince Charles Hospital
2021
University of Oxford
2021
Barro Colorado Island
2020
Arthur B. McDonald-Canadian Astroparticle Physics Research Institute
2019
Cleveland Clinic
2014-2016
Outcomes Research Consortium
2016
Stanford Medicine
2016
Disclaimer: The Extracorporeal Life Support Organization (ELSO) Coronavirus Disease 2019 (COVID-19) Guidelines have been developed to assist existing extracorporeal membrane oxygenation (ECMO) centers prepare and plan provision of ECMO during the ongoing pandemic. recommendations put together by a team interdisciplinary providers from around world. Recommendations are based on available evidence, best practice guidelines, ethical principles, expert opinion. This is living document will be...
Abstract Background The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships age, sex, and nationality to presenting symptoms. Methods International, 60 109 symptomatic laboratory-confirmed COVID-19 recruited from 43 countries between 30 January 3 August 2020. Logistic regression was performed evaluate age sex published case definitions most commonly reported Results ‘Typical’ symptoms fever (69%), cough...
Abstract The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases prospectively collected clinical data on people hospitalized with COVID-19. This was compiled during pandemic by a network hospitals that collect using ISARIC-World Health Organization Clinical Characterization Protocol tools. database includes from more than 705,000 patients, in 60 countries 1,500 centres worldwide. Patient are...
Purpose of review Surgical procedures on obese patients are dramatically increasing worldwide over the past few years. In this review, we discuss physiopathology predominantly respiratory system in patients, importance preoperative evaluation, preoxygenation and intraoperative positive end expiratory pressure (PEEP) titration to prevent pulmonary complications optimization airway management oxygenation reduce or postoperative complications. Recent findings Many coming clinic with medication...
Abstract Background Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive (IMV). We aimed describe the clinical characteristics, outcomes and risk factors for failing support in treated severe during first two years pandemic high-income countries (HICs) low middle-income (LMICs). Methods This is a multinational, multicentre, prospective cohort study embedded...
The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) is a global federation of clinical research networks that work collaboratively to prevent illness deaths from infectious disease outbreaks. In 2014, we proposed effective timely during outbreaks emerging infections would benefit pre-prepared tools, collaboration, research-ready networks.1 After applying this model several outbreaks, particularly the COVID-19 pandemic, can now explore what has been achieved date.
Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining relationship between COVID-19 AKI low- low-middle income countries (LLMIC) are lacking. Given that is known to carry a higher mortality rate these countries, it important understand differences this population.
Background Evidence suggests that recurrent nocturnal hypoxemia may affect pain response and/or the sensitivity to opioid analgesia. We tested hypothesis hypoxemia, quantified by sleep time spent at an arterial saturation (SaO2) < 90% and minimum SaO2 on polysomnography, are associated with decreased reduced consumption during initial 72 postoperative hours in patients having laparoscopic bariatric surgery. Methods With Institutional Review Board approval, we examined records of all who...
Research diversity and representativeness are paramount in building trust, generating valid biomedical knowledge, possibly implementing clinical guidelines.
By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and methodological limitations. It is highly important to develop predictive tools for pulmonary embolism (PE) patients as one the most severe preventable complications COVID-19. Early recognition can help provide life-saving targeted anti-coagulation therapy right...
Several continuous monitoring solutions, including wireless wearable sensors, are available or being developed to improve patient surveillance on surgical wards. We designed a survey understand the current perception and expectations of anaesthesiologists who, as perioperative physicians, increasingly involved in postoperative care.The was shared 40 university hospitals from Western Europe USA.From 5744 who received link, there were 1158 valid questionnaires for analysis. Current mainly...
Re-expansion pulmonary edema is defined as that occurs when a chronically collapsed lung rapidly re-expands, most commonly following chest tube placement for pneumothorax, re-expansion of severe atelectasis, and evacuation pleural effusion. Though it very rare, the sudden onset clinical features make lethal complication requires urgent treatment. We present 60-year-old patient who underwent an aortic valve replacement with pre-existing large bilateral effusions. Intraoperatively, upon...
Introduction By using a novel survey our study aimed to assess the challenges ECMO and Critical Care (CC) teams face when initiating managing patient's support. Methods A qualitative survey-based observational was performed of members 2 Medicine organizations involved in decision-making around practice Extracorporeal Membrane Oxygenation (ECMO). The range exploratory questions covered ethical principles informed consent, autonomy goals care discussions, beneficence, non-maleficence (offering...
Recurrent nocturnal hypoxemia in obstructive sleep apnea enhances sympathetic function, decreases baroreceptor sensitivity, and weakens peripheral vascular responses to adrenergic signals. The authors hypothesized that the percentage of total time spent at oxyhemoglobin saturation (SaO2) less than 90% minimum SaO2 on preoperative polysomnography are associated with decreased intraoperative mean arterial pressure.The examined records all patients who had laparoscopic bariatric surgery...
Background: Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is used as salvage therapy in severe cases of acute respiratory distress syndrome (ARDS) caused by the coronavirus disease 2019 (COVID-19). Obesity has been linked to worse severity and poor outcomes COVID-19, but there also a hypothesized obesity survival paradox whereby obese patients fare better illness than their non-obese complement. The effect on ECMO with COVID-19 not well understood. Methods: We performed...