A5080487855- Sexual Differentiation and Disorders
- Connective tissue disorders research
- Peripheral Neuropathies and Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Long-Term Effects of COVID-19
- Pediatric Urology and Nephrology Studies
- Testicular diseases and treatments
- Dermatological and Skeletal Disorders
- Growth Hormone and Insulin-like Growth Factors
- Multiple Sclerosis Research Studies
- Heterotopic Ossification and Related Conditions
- Hormonal and reproductive studies
- Cell Adhesion Molecules Research
- Diet, Metabolism, and Disease
- Adipokines, Inflammation, and Metabolic Diseases
- Systemic Lupus Erythematosus Research
- Ultrasound in Clinical Applications
- Parasitic infections in humans and animals
- Hedgehog Signaling Pathway Studies
- Adrenal Hormones and Disorders
- Thyroid and Parathyroid Surgery
- Polyomavirus and related diseases
- Thyroid Cancer Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Male Breast Health Studies
Dokuz Eylül University
2016-2021
Dr. Behçet Uz Çocuk Hastalıkları Hastanesi
2019-2021
Sağlık Bilimleri Üniversitesi
2019-2021
Ümraniye Eğitim ve Araştırma Hastanesi
2017-2019
Ege Üniversitesi Tıp Fakültesi Hastanesi
2017
Myelin oligodendrocyte glycoprotein (MOG) is a candidate target antigen in demyelinating central nervous system diseases, including acute disseminated encephalomyelitis (ADEM), neuromyelitis optica, and multiple sclerosis. It may give prognostic information regarding monophasic or recurrent course of the disease. MOG antibodies have been shown to be positive high titers during first episode ADEM with rapidly decreasing undetectable limits after recovery. However, persistent are considered as...
Background Diabetes and hepatosteatosis are dramatically increasing in childhood. Non-alcoholic fatty liver disease (NAFLD) is defined as a common disorder adulthood, especially with type-2 diabetes metabolic syndrome, while very few studies available on health children type-1 diabetes. Patients methods One hundred ten (52 males 58 females) patients aged between 8 18 years were examined. The lipid profile, enzymes hepatobiliary ultrasound findings of investigated terms hepatopathies....
Studies investigating clinical and imaging findings of coronavirus disease 2019 (COVID-19) pneumonia predictors for lung injury mostly focus on adults. In this study, we aimed to evaluate the role laboratory in predicting involvement children with COVID-19.Children COVID-19 confirmed by reverse-transcription polymerase chain reaction or IgM who underwent chest computed tomography (CT) scans were reviewed retrospectively. Admission absolute neutrophil count (ANC), lymphocyte (ALC), ANC/ALC...
Abstract Background Thyroid dysfunction is the most common hormonal abnormality in obesity. It should actually be considered as an adaptation response to fat excess. However, little has been reported on morphology of thyroid gland, and no data regarding relationship between gland changes metabolic parameters are available obese adolescents. Objective The study aimed evaluate frequency non-autoimmune thyroiditis adolescents compare status patients with or without thyroiditis. Methods A total...
Intratubular large cell hyalinizing Sertoli neoplasia (ITLCHSCN) resulting from cells of the testis are mainly reported in young adults and these rarely seen childhood. The most common presenting symptoms patients diagnosed with ITLCHSCN gynecomastia, enlargement testicles, increase growth velocity, advanced bone age. Symptoms basically increased aromatase enzyme activity cells. In this case report, an eight-and-a-half-year-old complaint bilateral gynecomastia since two years, showing no...
Myhre syndrome is a rare autosomal dominant multisystemic disorder. Typical features of this disorder include distinctive facial appearance, deafness, intellectual disability, cardiovascular abnormalities, short stature, brachydactyly, and skeletal anomalies. Gain-of-function mutations in the SMAD4 gene are responsible for syndrome. Herein, we present 9.6-year-old Turkish girl with molecularly confirmed who had novel findings including bilateral Axenfield Rieger anomaly secondary glaucoma...
Generalized arterial calcification of infancy (GACI) is a rare autosomal-recessive disorder, characterized by the internal elastic lamina, fibrotic myointimal proliferation muscular arteries and resultant stenosis.Treatment with bisphosphonates has been proposed as means reducing calcifications in GACI patients, although there no formalized treatment approach.The case reported here was patient severe diagnosed at three months age who had response to bisphosphonate treatment, but clinically...
ABS TRACTGrowth hormone (GH) deficiency is the most common pituitary after traumatic brain injury.Patients with GH have a reduced sweating capacity which increases risk of developing hyperthermia.To best our knowledge, central fever that developed due to and improved treatment has not yet been reported.In this article, we present case dramatic improvement recombinant human therapy in patient posttraumatic deficiency.
Craniofrontonasal syndrome (CFNS) is a rare X-linked genetic disorder which characterized by coronal synostosis, widely spaced eyes, central nasal groove, and various skeletal anomalies. Mutations in the EFNB1 gene Xq13.1 are responsible for familial sporadic cases. In present study, we aimed to evaluate clinical characteristics molecular results of 4 patients with CFNS. Genomic DNA was extracted from peripheral blood lymphocytes all their parents, Sanger sequencing performed. A novel...
We aimed to determine the presence of subclinical atherosclerosis using carotid intima-media thickness (CIMT) and biochemical parameters in children adolescents with congenital adrenal hyperplasia (CAH).Thirty-four patients classic due 21-hydroxylase deficiency on regular glucocorticoid treatment for ≥3 years 31 healthy subjects were included study. The divided into two groups according degree control clinic, laboratory, radiological as a) “uncontrolled” [n= 22; increased height velocity...
Autosomal recessive osteopetrosis is also known as infantile malignant (IMO). The clinical course often serious and if left untreated, it fatal in the 1st year of life. Diagnosis challenging delayed or misdiagnosed. Herein, we present an infant girl who was diagnosed with IMO during evaluations for her hypotonicity thrombocytopenia. A novel mutation chloride voltage-gated channel 7 (CLCN7) gene reported. 10-day-old female patient referred to our hospital evaluation hypotonicity. Her physical...
Turner syndrome (TS) is a genetic disease defined as complete or partial absence of the X chromosome. The incidence TS has been reported approximately 1 in 2500 female births. characterized by certain typical features, such short stature, primary amenorrhea, webbed neck, cubitus valgus, lymphedema (particularly during infancy), and cardiovascular renal abnormalities. Central nervous system (CNS) malformations are rarely seen patients. Agenesis corpus callosum (ACC) described only five...
Aim: The aim of this study was to present the sonographic characteristics follicular variant papillary thyroid carcinoma (FVPTC) related different forms nodules, including those without a capsule. Another purpose analyze color Doppler ultrasonography (CDUS) features unique tumor, which have not been intensively studied in previous works.Materials and Methods: Twenty-two nodules (male/female: 17/5; mean age±SD: 42±16 years; range: 17-70) diagnosed with FVPTC were included study. analyzed...
Hyperoxaluria is characterized by nephrolithasis and nephrocalcinosis caused supersaturation of calcium oxalate in the urine. Deposits can lead to kidney damage, failure, injury other organs. Herein, we report a case primary hyperoxaluria which serious though rare condition, be suspected on basis renal features. Radiological skeletal changes, are also rather specific, may share some features with osteodystrophy.
The diagnosis and management of pulmonary hydatid cyst disease represents an important clinical problem in countries the world that are endemic to echinococcal infection.Atypical radiologic findings including multiple cavitary lesions lung pleural effusion may lead misdiagnosis or delay these patients.We report a patient who was followed up our hospital with rashes and, necrotizing pneumonia whom there no response broad spectrum antibiotherapy.Lung computed tomography showed thick-walled...
What is already known on this topic?Generalized arterial calcification of infancy (GACI) a rare disease that associated with high mortality rate owing to the development severe hypertension and cardiovascular complications.GACI can begin in utero during third trimester, 50% children GACI present well-developed large calcifications within first week life.Although there no definitive treatment, it claimed patients treated bisphosphonates have better survival rates.In contrast, not were also...