Xiangmao Bu

ORCID: 0000-0002-1567-3510
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About
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Research Areas
  • Blood groups and transfusion
  • Erythrocyte Function and Pathophysiology
  • IL-33, ST2, and ILC Pathways
  • Viral gastroenteritis research and epidemiology
  • Neonatal Respiratory Health Research
  • Genomics and Rare Diseases
  • Renal and related cancers
  • Neonatal Health and Biochemistry
  • Cystic Fibrosis Research Advances
  • Blood disorders and treatments
  • Diabetes and associated disorders
  • Animal Virus Infections Studies
  • Mosquito-borne diseases and control
  • Pancreatic function and diabetes
  • Monoclonal and Polyclonal Antibodies Research
  • Immune Cell Function and Interaction
  • Chronic Lymphocytic Leukemia Research
  • Cancer Cells and Metastasis
  • Malaria Research and Control
  • Cancer-related Molecular Pathways
  • Immunodeficiency and Autoimmune Disorders
  • Pediatric Hepatobiliary Diseases and Treatments
  • Appendicitis Diagnosis and Management
  • Hepatitis B Virus Studies
  • Cell Adhesion Molecules Research

Qingdao Women and Children's Hospital
2013-2025

Qingdao University
2013-2025

Peking University People's Hospital
2025

Peking University
2025

Autoimmune hemolytic anemia (AIHA), a life-threatening with rapid onset, is caused by autoantibody directed to self red blood cells (RBCs). Currently, mechanisms underlying AIHA pathogenesis are largely undefined. Here we explored the correlation of IL-33 disease activity and evaluated based therapeutics in treatment. Thirty patients diagnosed warm-type autoantibodies without treatment were enrolled followed up for 6 months. Levels cytokines including IL-33, IL-4, IL-6 IL-13 was determined...

10.1186/s12967-015-0745-0 article EN cc-by Journal of Translational Medicine 2015-12-01

Background: Cohen syndrome (CS) is a clinically heterogeneous disorder characterized by extensive phenotypic variation with autosomal recessive inheritance. VPS13B was identified to be the disease-causing gene for CS. The objectives of present study were screen likely pathogenic mutations patient developmental delay and mental retardation, determinate effect this splice-site mutation reverse transcription analysis. Methods: Whole exome sequencing (WES) in combination Sanger performed...

10.3389/fped.2021.651621 article EN cc-by Frontiers in Pediatrics 2021-04-20

Acute appendicitis is the most common surgical emergency in pediatrics. In this study, we aimed to evaluate diagnostic value of D-dimer differentiating between simple and other severe acute children combined with white blood cell (WBC) count, neutrophil percentage, C-reactive protein (CRP).A retrospective study enrolled 327 consecutive patients who underwent appendectomy for (aged 13 days 14 years) Qingdao Women & Children's Hospital from Jan 2013 Dec 2014. WBC CRP, levels were measured....

10.7754/clin.lab.2016.160122 article EN Clinical Laboratory 2016-01-01

The authors have disclosed no conflicts of interest.

10.1111/trf.15804 article EN Transfusion 2020-04-24

Since the discovery of ABO blood types, there has been mounting evidence association between types and infectious diseases. However, so far, is rarely available research about potential role in haemorrhagic fever with renal syndrome (HFRS) infection. Our aim was to investigate relationship development HFRS infection Qingdao, China. We carried out a retrospective study enrolling 116 patients as case group 373 healthy subjects control group. type distribution analysed using Chi-square test...

10.1017/s0950268821002168 article EN cc-by-nc-nd Epidemiology and Infection 2021-09-29

A term-born, Chinese male neonate was transferred to our hospital following detection of jaundice and anaemia 6 hours after birth. His haemoglobin concentration 104 g/l with a red blood cell count (RBC) 2·72 × 1012/l robust compensatory haematological response: reticulocytes 7·72%, absolute reticulocyte 218·5 109/l production index 3·30 (normal range 0·2–1·5). peripheral film showed spherocytes, polychromatic cells, occasional nucleated RBCs fragments (left panel, ×100 objective;...

10.1111/bjh.17133 article EN British Journal of Haematology 2020-11-22

COVID-19 and malaria share some similar symptoms such as fever, difficulty in breathing, fatigue, headaches of acute onset. With overlapping travel history significant for malaria, healthcare systems professionals will face a great challenge the case co-infection.Here we presented patient with infection refractory anemia unknown reason. A diagnostic test was later performed.The ultimately diagnosed plasmodium falciparum co-infection. He recovered gradually after receiving anti-malaria...

10.7754/clin.lab.2022.220402 article EN Clinical Laboratory 2023-01-01

CF is considered a rare disease among the non-Caucasian population. The clinical phenotypes and genotypic spectrum of Chinese patients are reported to be different from that observed in Caucasians[(1)](#ref-0001). Our patient carried compound heterozygous mutations which not included Caucasian CFTR common mutation-screening panel have been yet. dysfunction causes diseases, with range number organs involved varying severity. Typical phenotypic features include respiratory diseases...

10.22541/au.168017416.60603233/v1 preprint EN Authorea (Authorea) 2023-03-30

The authors declare no potential conflict of interest.

10.1111/trf.16182 article EN Transfusion 2020-11-04

The authors have disclosed no conflicts of interest.

10.1111/trf.17121 article EN Transfusion 2022-09-28
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