- Healthcare Education and Workforce Issues
- Education and Learning Interventions
- Protease and Inhibitor Mechanisms
- Diverse Approaches in Healthcare and Education Studies
- Second Language Acquisition and Learning
- Hydrocarbon exploration and reservoir analysis
- Cloud Computing and Resource Management
- Health and Wellbeing Research
- HER2/EGFR in Cancer Research
- Enhanced Oil Recovery Techniques
- EFL/ESL Teaching and Learning
- Second Language Learning and Teaching
- Neurogenesis and neuroplasticity mechanisms
- Discourse Analysis in Language Studies
- Stroke Rehabilitation and Recovery
- TGF-β signaling in diseases
- Epigenetics and DNA Methylation
- Distributed and Parallel Computing Systems
- Advanced Data Storage Technologies
- Innovative Teaching and Learning Methods
- Educational Systems and Policies
- vaccines and immunoinformatics approaches
- IoT and Edge/Fog Computing
- Metabolomics and Mass Spectrometry Studies
- Nursing education and management
Kunsan National University
2019-2024
Korea Institute of Science and Technology
2023
Korea University of Science and Technology
2023
Korea Institute of Science & Technology Information
2023
Oregon Health & Science University
2019-2022
Reservoir Engineering Research Institute
2020-2021
University of Utah
2017-2020
Catholic University of Korea
2018
Family Research Institute
2017
Korea Advanced Institute of Science and Technology
2007-2016
[Purpose] The aim of the present study was to investigate effects a virtual reality exercise program (VREP) on physical fitness, body composition, and fatigue in hemodialysis (HD) patients with end-stage renal failure. [Subjects Methods] A nonequivalent control group pretest-posttest design used. Forty-six HD were divided into (n=23) groups (n=23); while waiting for their dialyses, followed VREP, received only usual care. VREP accomplished using Nintendo's Wii Fit Plus 40 minutes, 3 times...
Abstract Despite the crucial physiological processes governed by neurons in hypothalamic arcuate nucleus (ARC), such as growth, reproduction and energy homeostasis, developmental pathways regulators for ARC remain understudied. Our single cell RNA-seq analyses of mouse embryonic revealed many type-specific markers developing neurons. These include transcription factors whose expression is enriched specific neuronal types often depleted other closely-related types, raising possibility that...
Abstract The net balance of matrix metalloproteinases (MMP) and tissue inhibitor (TIMP) system has been known to be a key factor in tumor cell invasion. In the present study, we investigated molecular mechanisms anti-invasive antimigrative activity transforming growth (TGF)-β1 on HT1080 human fibrosarcoma cells. vitro Matrigel invasion Transwell migration assays, TGF-β1 dose-dependently inhibited cells, respectively. Gelatin zymography, Western blot, real-time PCR analysis showed that...
The phase behavior change when fluids are in a confined system has been an important issue after shale reservoirs became the focus of new oil and gas resources. Most studies on fluid systems have focused modeling pore size dependence upon critical properties with no direct experimental evidence. Direct bubble point measurements hydrocarbon mixtures two synthesized mesoporous materials provided this work. Two different silica materials, SBA-15 SBA-16, having similar sizes (namely, 4 nm), were...
The shale play resources have played a key role in increasing oil production the past decade United States. sizes of pores shales storing are believed to be on order nanometers. It is that fluids present such small nanometer-scale different properties compared measured bulk. Fluid saturation pressures at given temperatures, bubble points for oils and dew condensates, nanopores affected by influence pore walls vicinity fluid molecules. An approach point or influences proportion liquid gas...
PRC2 creates the repressive mark histone H3 Lys27 trimethylation. Although is involved in various biological processes, its role glial development remains ambiguous. Here, we show that required for oligodendrocyte (OL) differentiation and myelination, but not OL precursor formation. PRC2-deficient lineage cells differentiate into precursors, they fail to trigger molecular program highlighting essential directing timing of precursors. null aberrantly induce Notch pathway genes acquire...
Abstract How a single neuronal population diversifies into subtypes with distinct synaptic targets is fundamental topic in neuroscience whose underlying mechanisms are unclear. Here, we show that the histone H3-lysine 27 demethylase Kdm6b regulates diversification of motor neurons to innervating different muscle during spinal cord development. In mouse embryonic neurons, promotes medial column (MMC) and hypaxial (HMC) fates while inhibiting lateral (LMC) preganglionic (PGC) identities. Our...
Abstract CD95/Fas is a cell surface protein that belongs to the tumor necrosis factor receptor family. Signals through are able induce apoptosis in sensitive cells. Therefore, modalities regulate expression level cells called for. In present study, we show sublethal doses of arsenic trioxide (As 2 O 3 ) sensitized CD95/Fas‐induced human cervical cancer cells, and sensitizing effects resulted from As ‐mediated increase CD95/Fas. N‐acetyl‐ L ‐cysteine, specific scavenger reactive oxygen...
Background: Addictive use of the Internet and online games is a potential psychiatric disorder termed gaming (IGD). Altered microRNA (miRNA) expression profiles have been reported in blood brain tissue patients with certain disorders suggested as biomarkers. However, there no reports on miRNA IGD. Methods: To discover IGD-associated miRNAs, we analyzed 51 samples (25 IGD 26 controls) using TaqMan Low Density Array. For validation, performed qRT-PCR 36 independent (20 16 controls). Results:...
Biomarkers that are identified from a single study often appear to be biologically irrelevant or false positives. Meta-analysis techniques allow integrating data multiple studies related but independent in order identify biomarkers across conditions. However, existing biomarker meta-analysis methods tend sensitive the dataset being analyzed. Here, we propose method, iMeta, which integrates t-statistic and fold change ratio for improved robustness. For evaluation of predictive performance by...
Abstract Nanoconfined water plays a pivotal role in vast number of fields ranging from biological and materials sciences to catalysis, nanofluidics geochemistry. Here, we report the freezing melting behavior (D 2 O) nanoconfined architected silica-based matrices including Vycor glass mesoporous silica SBA-15 SBA-16 with pore diameters between 4–15 nm, which are investigated using differential scanning calorimetry H nuclear magnetic resonance spectroscopy. The results provide compelling...
The purpose of this study was to analyze the effects task-oriented circuit training on balance ability and gait endurance chronic stroke inpatients.[Subjects Methods] participants were 30 patients who had >6 months previously, resulting in a disability such as hemiparesis.The randomly divided into group individual circuittraining group.They performed eight types modified training.Balance measured by using Berg scale questionnaire 6-min walk test, respectively, before after...
The aim of this study was to investigate the effect environmental enrichment (EE) on neurotrophin expression in an animal model Parkinson’s disease (PD). PD induced via intraperitoneal injection 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Male mice ( N = 42) were randomly divided into 3 groups: control, MPTP + standard condition (SC), and EE. groups raised separately for 28 days. On Day 21 they received 1 (20 mg/kg or saline control groups, respectively) every 2 hr a total 4...
[Purpose] The purpose of this study was to investigate the effects whole-body vibration exercise (WBVE) on isokinetic muscular function knee and jump performance depending different squatting positions. [Subjects] subjects were 12 healthy adult men who did not regularly between ages 27 34. [Methods] WBVE performed with high squat position (SP), middle SP, low SP. Before after intervention, knees measured. [Results] Knee flexion peak torque at 60°/s total work 180°/s significantly increased...
Bimodal reinforcement consisting of powders large graphite flakes (GF) and small graphene nanoplatelets (GNP) were used to fabricate (GF+GNP)/Cu composites reduce the anisotropy thermal mechanical properties in GF/Cu composites. In this study, we investigated effects GNP addition on deformation behavior The <cos2 θ > value was evaluate alignment reinforcing phases (GF, GNP), by which variations coefficient expansion (CTE) conductivity (TC) analyzed. With increasing volume fraction, angle (θ)...
Abstract Aim This study attempted to investigate the effects of a self‐performance management video program using tablet PC on self‐care knowledge, behavior, state anxiety and physiological index in patients receiving hemodialysis. Methods was an experimental research design. The participants this were 46 who diagnosed with end‐stage renal failure received hemodialysis regular basis kidney centers (23: group, 23: control group). data collection period from November 24, 2016 January 3, 2017....
Purpose: The purpose of this study was to investigate interpersonal competence and social support their mediating effects on the relationship between caring efficacy empathy in nursing students. Methods: This used a cross-sectional design. Data collection conducted from February 5 12, 2019, 254 students enrolled Department Nursing Jeollabuk-do Chungcheongbuk-do. analysis using SPSS/WIN 21.0 program. Results: As result verifying ability college students, it found that partially mediated two...