A5032550420- Ultrasound in Clinical Applications
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Hemodynamic Monitoring and Therapy
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Cardiovascular Health and Disease Prevention
- Cardiovascular and exercise physiology
- Heart Failure Treatment and Management
- Blood Pressure and Hypertension Studies
- ECG Monitoring and Analysis
- Cardiomyopathy and Myosin Studies
- Cardiovascular Issues in Pregnancy
- Infective Endocarditis Diagnosis and Management
- Pulmonary Hypertension Research and Treatments
- Thermal Regulation in Medicine
- Congenital Heart Disease Studies
- Pharmacological Effects and Toxicity Studies
- Cardiac Arrest and Resuscitation
- Cardiovascular Effects of Exercise
IRCCS Humanitas Research Hospital
2025
Vita-Salute San Raffaele University
2020-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2022-2024
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2022-2024
IRCCS Ospedale San Raffaele
2021-2024
Maasstad Ziekenhuis
2023
Erasmus MC
2023
Abstract Aims Transcatheter aortic valve implantation (TAVI) is the treatment of choice for high-risk patients with severe stenosis (AS). A portion TAVI recipients has no long-term clinical benefit, and myocardial fibrosis may contribute to unfavourable outcomes. We aimed assess prognostic value an interstitial marker, extracellular volume fraction (ECV), measured at planning computed tomography (CT) before TAVI. Methods results From October 2020 July 2021, 159 consecutive undergoing CT were...
The initial bundle of cares strongly affects haemodynamics and outcomes in acute decompensated heart failure cardiogenic shock (ADHF-CS). We sought to characterize whether 24 h haemodynamic profiling provides superior prognostic information as compared with admission assessment which parameters best predict in-hospital death.
Abstract Aims Impella malrotation—inlet orientation away from the left ventricular (LV) apex with normal console waveforms and proper device depth—is commonly observed possibly associated worse haemodynamics. This study aimed to characterize haemodynamic consequences of malrotation in cardiogenic shock (CS) patients. Methods results We included 100 CS patients (60 ± 12 years; 79.0% males) available echocardiography during support pulmonary artery catheter assessment before (at 48 h) support....
Objectives Coronavirus disease 2019 (COVID‐19) is a viral illness caused by severe acute respiratory syndrome coronavirus 2. With the increasing number of improved and discharged patients with COVID‐19, definition an adequate follow‐up strategy needed. The purpose this study was to assess whether lung ultrasound (LUS) effective indicator subclinical residual damage in COVID‐19 who meet discharge criteria. Methods We prospectively enrolled 70 consecutive had prolonged hospitalization...
Abstract Funding Acknowledgements Type of funding sources: None. Background Measurement cardiac index (CI) is crucial in the hemodynamic assessment critically ill patients. Pulmonary artery catheterization (PAC) remains gold standard for CI evaluation, but it's invasive. Doppler trans-thoracic echocardiography (TTE) has been proposed as an accurate bedside non-invasive alternative to PAC estimation, based on measurement left ventricular outflow tract velocity time integral (LVOT-VTI) and...
Abstract Aim The initial bundle of cares strongly affects hemodynamics in acute decompensated heart failure cardiogenic shock (ADHF–CS). We sought to characterize whether 24–hour hemodynamic profiling provides superior prognostic information as compared admission assessment, and which parameters best predict in–hospital death. Methods results included 99 patients (62±14 years, 24.2% females) with ADHF–CS available invasive assessment from two academic institutions. Overall, mortality was...
Abstract Background In patients with mild to moderate Alzheimer's disease (AD), acetylcholinesterase inhibitors (AChE-I) are commonly employed improve cognitive function. They increase the amount of acetylcholine (ACh) in neuronal synapses, but bradycardia, cardiac electrical conduction blocks and hypotension due muscarinic M2 receptor stimulation potential side effects. However, whether these "side effects" could play a protective effect on cardiovascular (CV) events is not yet well...
Abstract Background Several electrocardiogram (ECG) criteria have been proposed to predict the location of culprit occlusion in specific subsets patients presenting with ST-segment elevation myocardial infarction (STEMI). Purpose The aim this study was develop, through an independent validation currently available criteria, a comprehensive and easy-to-use ECG algorithm, test its diagnostic performance reliability real-world clinical practice. Methods We analyzed angiographic data from 408...
Abstract Background and aim Measurement of cardiac index (CI) is crucial in the hemodynamic assessment critically ill patients intensive care unit (ICU). The most reliable trans-thoracic echocardiography (TTE) technique for CI estimation left ventricular outflow tract (LVOT) Doppler method that requires, among other parameters, LVOT cross-sectional area (CSA) measurement. However, geometrical assumptions inherent limitations practical disadvantages related to ICU setting, hamper LVOT-CSA...
Abstract Background The inodilator levosimendan has shown improved outcomes in acute heart failure (AHF) and cardiac surgery. Its hemodynamic effect is persistent, owing to a long (70-80 hours) elimination half-life of its active metabolites. No robust data available the use patients with severe renal (SRF), thus contraindicated estimated glomerular filtration rate (eGFR≤30 mL/min). Hypothesis Different pharmacokinetics due may alter metabolites elimination, causing more pronounced effects....
Introduction: The disease caused by the SARS-CoV-2 virus (COVID-19) frequently leads to serious complications and prolonged hospitalizations requiring effective care after discharge. Aim of study: this study was identify feasible cost-effective predictors outcome among clinical characteristics, functional status, laboratory, echocardiographic lung ultrasound data COVID-19 patients. Material methods: Patients affected who experienced a hospitalization due severe form that have been discharged...