PURPOSE:To predict programmed death-ligand 1 (PD-L1) expression of tumor cells in non-small cell lung cancer (NSCLC) patients by using a radiomics study based on CT images and clinicopathologic features. MATERIALS AND METHODS:A total 390 confirmed NSCLC who performed chest scan i mmunohistochemistry (IHC) examination PD-L1 tumors with clinic data were collected this retrospective study, which divided into two cohorts namely, training (n = 260) validation 130) cohort. Clinicopathologic...

PURPOSE:To explore the radiomics features of triple negative breast cancer (TNBC) and non-triple (non-TNBC) based on X-ray mammography, to differentiate two groups cases. MATERIALS AND METHODS:Preoperative mammograms 120 patients with ductal carcinoma con firmed by surgical pathology were retrospectively analyzed, which include 30 TNBC 90 non-TNBC patients. The manual segmentation lesions was performed ITK-SNAP software 12 extracted Omni-Kinetics software. differences these between compared,...

To test the feasibility of differentiate gastric cancer from stromal tumor using a radiomics study based on contrast-enhanced CT images.The image data 60 patients with and 40 confirmed by postoperative pathology were retrospectively analyzed. First, images read two senior radiologists to acquire subjective signs model, including perigastric fatty infiltration, enlarged lymph nodes, enhancement growth modes tumors. Second, manual segmentation tumors was performed extract features via ITK-SNAP...

Background: Cervical lymph node (LN) metastasis of papillary thyroid carcinoma (PTC) is critical for treatment and prognosis. To examine the feasibility MRI radiomics to preoperatively predict cervical LN in patients with PTC. Methods: Between January 2015 March 2018, a total 61 pathologically confirmed PTC were analyzed retrospectively. The divided into group (n = 37) no 24). T2WI T2WI-fat-suppression (T2WI-FS) images collected. A number radiomic features automatically extracted from...

To delineate the features of multi-detector computed tomography (MDCT) images and clinical characteristics pancreatic solid pseudopapillary tumors (SPTs) pancreas in asymptomatic patients compare these between symptomatic patients. This work is a retrospective study approved by our institutional review board. MDCT data 109 with pathologically proven SPTs obtained from October 2008 to 2016 were reviewed. Patients categorized into two groups: disease. Cases reviewed determine reason for...

PURPOSE: To investigate feasibility of predicting Lauren type gastric cancer based on CT radiomics nomogram before operation. MATERIALS AND METHODS: The clinical data and pre-treatment images 300 patients with intestinal or diffuse confirmed by postoperative pathology were retrospectively analyzed, who randomly divided into training set testing a ratio 2:1. Clinical features compared between the two types in set, respectively. Gastric tumors manually segmented using ITK-SNAP software,...

This study aimed to explore the value of native T1-mapping and diffusion-weighted imaging (DWI) in differentiating pathological types degree tumor differentiation lung cancer their correlation with Ki-67 protein expression.A total 78 consecutive patients who received chest magnetic resonance (MRI) scans between May 2020 June 2021 were enrolled this study. Two radiologists independently analyzed apparent diffusion coefficient (ADC) T1 values for each lesion. The intraclass (ICC) Bland-Altman...

Purpose: To explore the separate diagnostic value of preoperative ultrasound (US), magnetic resonance imaging (MRI), and combination US MRI in extrathyroidal extension (ETE) papillary thyroid carcinoma (PTC). Materials Methods: This retrospective study was approved by Affiliated People's Hospital Jiangsu University review board. A total 158 PTC patients with ETE received examination underwent surgery between May 2014 December 2018 University. For each case, features were retrospectively...

To evaluate the efficacies of 125I seed implantation and stereotactic body radiation therapy (SBRT) in treatment recurrent lung metastases from colorectal cancer, to compare tolerance tissue both forms radiotherapy, analyze factors that affect prognosis.According received, thirty cancer patients with post-operative were separated into two groups: group (group A; n = 16) SBRT B; 14). Patients followed up, local control rate, survival, complications analyzed retrospectively. Kaplan-Meier...

Rationale and ObjectivesTo evaluate whether quantitative diffusion-weighted MR imaging (DWI) with multi-b values can be used as a tool to predict the aggressiveness by using histological feature of extrathyroidal extension (ETE) in papillary thyroid carcinoma (PTC).Materials Methods238 patients were pathologically confirmed PTCs underwent preoperative value DWI (300, 500, 800 s/mm2) between January 2015 December 2017. The divided into three groups according degree ETE: without ETE, minimal...

Background Differentiating nasopharyngeal carcinoma (NPC) from lymphoma (NPL) is useful for deciding the appropriate treatment. However, diagnostic accuracy of current imaging methods low. Purpose To explore feasibility arterial spin labeling (ASL) perfusion in qualitative and quantitative differentiation between NPC NPL to improve diagnosis malignancies nasopharynx. Study Type Retrospective. Population Ninety seven patients: (65 cases) (32 cases), histologically confirmed. Field...

PURPOSE: To explore the characteristics of variously differentiated gastric cancers on computed tomography (CT) perfusion imaging, including specific parameter values, and potential clinical applications in prognosis assessment cancer. MATERIALS AND METHODS: Fifty patients with cancer confirmed by gastroscope pathology were studied prospectively using CT imaging examinations a 64-slice spiral scanner. The acquired volume data used for calculations, mapping, analysis an abdominal tumor...

The aim of the study was to determine how many times iodine-125 (125I) seed brachytherapy (ISB) for recurrent pulmonary metastases (RPM) can be done, and clinical efficacy complications repeated ISB in RPM treatment.Between September 2013 August 2018, 18 patients with RPM, after conventional chemotherapy, radiotherapy, trans-arterial chemoembolization, received CT-guided ISB. Patients were followed up, local control, survival, post-operative analyzed retrospectively. Kaplan-Meier method used...

Immunotherapy is an effective way to treat non-small cell lung cancer (NSCLC). The efficacy of immunotherapy differs from person and may cause side effects, making it important predict the before surgery. Radiomics based on machine learning has been successfully used NSCLC immunotherapy. However, most studies only considered radiomic features individual patient, ignoring inter-patient correlations. Besides, they usually concatenated different as input a single-view model, failing consider...

To evaluate the clinical efficacy and safety of computed tomography (CT)-guided iodine-125 (125I) seed implantation (ISI) for hepatocellular carcinoma (HCC) or cholangiocellular (CCC) lesions in challenging locations after transcatheter arterial chemoembolization (TACE). A retrospective single-center review 24 patients with HCC CCC tumors (hepatic dome close to heart/diaphragm/hepatic hilum) was conducted. Patients who underwent CT-guided 125I from May 2014 January 2019 were recruited....

OBJECTIVE: To investigate efficiency of radiomics signature to preoperatively predict histological features aggressive extrathyroidal extension (ETE) in papillary thyroid carcinoma (PTC) with biparametric magnetic resonance imaging findings. MATERIALS AND METHODS: Sixty PTC patients preoperative MR including T2WI and T2WI-fat-suppression (T2WI-FS) were retrospectively analyzed. Among them, 35 had ETE 25 did not. Pre-contrast T2WI-FS images depicting the largest section tumor selected. Tumor...

Objective: To investigate whether diffusion-weighted MRI (DWI) with multi b values can be used as a quantitative assessment tool to predict central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC). Method: PTCs patients were enrolled from January 2015 April 2018. Each patient was measured value DWI (300, 500, and 800 s/mm2) preoperative then underwent clinical treatment of dissection at the surgery department. These without CLNM divided two groups. The apparent diffusion...

PURPOSE: To investigate the feasibility of predicting early response to neoadjuvant chemotherapy (NAC) in advanced gastric cancer (AGC) based on CT radiomics nomogram before treatment. MATERIALS AND METHODS: The clinicopathological data and pre-treatment portal venous phase images 180 consecutive AGC patients who received 3 cycles NAC are retrospectively analyzed. They randomly divided into training set (n = 120) validation 60) categorized effective group 83) ineffective 97) according RECIST...