A5053367431- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Sexual Differentiation and Disorders
- Sperm and Testicular Function
- Hernia repair and management
- Male Reproductive Health Studies
- Urinary and Genital Oncology Studies
- Bladder and Urothelial Cancer Treatments
- Urinary Tract Infections Management
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Diversity and Career in Medicine
- Kidney Stones and Urolithiasis Treatments
- Ureteral procedures and complications
- Congenital Heart Disease Studies
- Congenital heart defects research
- Urologic and reproductive health conditions
- Testicular diseases and treatments
- Vascular anomalies and interventions
- Gastroesophageal reflux and treatments
- Health and Medical Research Impacts
- Renal cell carcinoma treatment
- Healthcare Policy and Management
- Congenital Diaphragmatic Hernia Studies
Children's Hospital of Philadelphia
2016-2025
University of Pennsylvania
2016-2025
Philadelphia University
2016-2023
University of Wisconsin–Madison
2023
Hospital of the University of Pennsylvania
2022
GTx (United States)
2020
New York Proton Center
2012-2018
Columbia University Irving Medical Center
2009-2017
Morgan Stanley Children's Hospital
2009-2017
Urology of Indiana
2017
It is recognized that there a strong association between bladder and bowel dysfunction. We determined the of constipation and/or encopresis with specific lower urinary tract conditions.We reviewed our database children dysfunction divided cases into 3 categories (constipation, plus encopresis) 4 conditions (dysfunctional voiding, idiopathic detrusor overactivity disorder, underutilization disorder primary neck dysfunction). Associations types each condition were determined.Of 163 males 205...
No AccessJournal of UrologyPediatric Urology1 Aug 2020Time to Complication Detection after Primary Pediatric Hypospadias Repair: A Large, Single Center, Retrospective Cohort AnalysisThis article is commented on by the following:Editorial Comment Jacob Lucas, Tyler Hightower, Dana A. Weiss, Jason Van Batavia, Simmona Coelho, Arun K. Srinivasan, Aseem R. Shukla, Steven Zderic, Thomas F. Kolon, Mark Zaontz, Douglas Canning, and Christopher J. Long LucasJacob Lucas Department Urology, Einstein...
Variability in the interpretation of videourodynamics studies limits reliable classification kidney injury risk for patients with spina bifida. We developed machine learning models to predict incident hydronephrosis bifida using data. trained data from performed between 2016 and 2022 on aged 2 months 42 years. evaluated performance four following an index study: 1) random survival forest model prospectively abstracted by urologists, 2) bladder volume-pressure data, 3) utilizing deep features...
Noninvasive uroflowmetry with simultaneous electromyography is useful to triage cases of lower urinary tract symptoms into 4 urodynamically defined conditions, especially when incorporating short and long lag times in the analysis. We determined prevalence these conditions at a single referral institution usefulness time confirm diagnosis, guide treatment monitor response.We retrospectively reviewed records 100 consecutive normal children who presented persistent symptoms, underwent as part...
Widespread utilization of telemedicine in our practice to date has been limited the evaluation certain post-surgical patients. The COVID-19 pandemic acutely stressed established system and required us enhance telemedicine. We hypothesized that expansion new follow up patient visits for pediatric urology could be done effectively a way satisfied parental expectations.Using pre-COVID-19 program based electronic medical record (EMR), patients providers transitioned primarily virtual when...
Urologists rely heavily on videourodynamics to identify patients with neurogenic bladders who are at risk of upper tract injury, but their interpretation has high interobserver variability. Our objective was develop deep learning models studies categorize severity bladder dysfunction.We performed a cross-sectional study aged 2 months 28 years spina bifida underwent single institution between 2019 and 2021. The outcome degree dysfunction, defined as none/mild, moderate, severe, by panel 5...
In both animal cells and the eubacterium Deinococcus radiodurans, Ro autoantigen, a ring-shaped RNA-binding protein, associates with small RNAs called Y RNAs. vertebrates, also binds 3' ends of misfolded is proposed to function in quality control. However, little known about vivo. Here, we report that D. radiodurans ortholog Rsr (Ro sixty related) functions exoribonucleases 23S rRNA maturation. During normal growth, maturation inefficient, resulting accumulation precursors containing 5'...
Lower urinary tract dysfunction is a common pediatric urological problem that often associated with infection. We determined the prevalence of infection history in children lower and its association, if any, gender, bowel dysfunction, vesicoureteral reflux specific conditions.We retrospectively reviewed charts diagnosed treated for noting or without fever, association conditions.Of 257 boys 366 girls mean age 9.1 years 207 (33%) had history, including 88 at least 1 febrile A total 64...
Testicular asymmetry in adolescents with varicocele can worsen, remain unchanged or decrease on followup. We determined the incidence of testicular at presentation by Tanner stage and correlation between subsequent changes percent (ability for catch-up growth progressive asymmetry) without surgical intervention.We retrospectively studied records 115 boys a mean age 14.1 years (range 9.2 to 20.0) grade 2 3 left who underwent volume measurement visits least that were minimum 6 months apart. Of...