Douglas A. Canning

ORCID: 0000-0003-4998-2669
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About
Contact & Profiles
Research Areas
  • Urological Disorders and Treatments
  • Pediatric Urology and Nephrology Studies
  • Urologic and reproductive health conditions
  • Hernia repair and management
  • Sexual Differentiation and Disorders
  • Testicular diseases and treatments
  • Urinary Bladder and Prostate Research
  • Urinary and Genital Oncology Studies
  • Ureteral procedures and complications
  • Genital Health and Disease
  • Bladder and Urothelial Cancer Treatments
  • Urinary Tract Infections Management
  • Renal and related cancers
  • Congenital gastrointestinal and neural anomalies
  • Adolescent and Pediatric Healthcare
  • Sperm and Testicular Function
  • Tissue Engineering and Regenerative Medicine
  • Pelvic floor disorders treatments
  • Congenital Anomalies and Fetal Surgery
  • Kidney Stones and Urolithiasis Treatments
  • Congenital Diaphragmatic Hernia Studies
  • Ethics and Legal Issues in Pediatric Healthcare
  • Renal and Vascular Pathologies
  • Healthcare Policy and Management
  • Male Reproductive Health Studies

Children's Hospital of Philadelphia
2014-2024

University of Pennsylvania
2012-2023

Evidence (Italy)
2023

Michigan Department of Education
2023

American Urological Association
2023

Philadelphia University
2012-2022

Hospital of the University of Pennsylvania
2004-2022

Utrecht University
2019

Amsterdam UMC Location Vrije Universiteit Amsterdam
2019

Boston Children's Museum
2017

No AccessJournal of UrologyPediatric Urology1 May 1996The Long-Term Outcome Posterior Urethral Valves Treated with Primary Valve Ablation and Observation Grahame H.H. Smith, Douglas A. Canning, Seth L. Schulman, Howard M. Snyder, John W. Duckett SmithGrahame Smith More articles by this author , CanningDouglas Canning SchulmanSeth Schulman SnyderHoward Snyder DuckettJohn View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66186-XAboutFull TextPDF ToolsAdd to favoritesDownload...

10.1016/s0022-5347(01)66186-x article EN The Journal of Urology 1996-05-01

Color Doppler sonography was performed in 32 patients with a painful scrotum whom testicular ischemia from torsion or postherniorrhaphy clinically suspected. Surgical correlation available 15 patients, and scintigraphic 17 patients. Seven of the were diagnosed as having torsion. flow imaging demonstrated lack intratesticular six seven testes relatively normal one acute Normal increased by color all 57 nonischemic testes. Using single criterion presence absence identifiable flow, authors...

10.1148/radiology.175.3.2188301 article EN Radiology 1990-06-01

Results following distal hypospadias repair are favorable. Grouping proximal and artificially increases the perceived success rate of hypospadias. We identified our complication hypothesized a higher for 1-stage repair.We retrospectively reviewed records consecutive boys who underwent from 2007 to 2014. Proximal was defined as urethral meatus location at or more than penoscrotal junction after penile degloving. further stratified into those with planned vs 2-stage repair. Univariate Cox...

10.1016/j.juro.2016.11.054 article EN The Journal of Urology 2016-11-10

<i>Background:</i> Previous studies suggest that two fundamental, probably androgen-dependent, steps in maturation of germ cells normally occur the prepubertal testis: disappearance gonocytes (the fetal stem cell pool) and appearance adult dark spermatogonia at 2–3 months age primary spermatocytes onset meiosis) 4–5 years. small series cryptorchid boys both are defective undescended testes to a lesser degree descended contralateral unilaterally testes. The purpose this study is...

10.1159/000049957 article EN Hormone Research in Paediatrics 2001-01-01

No AccessJournal of UrologyPEDIATRIC UROLOGY1 Dec 2002Spontaneous Resolution Vesicoureteral Reflux: A 15-Year Perspective C. WILLIAM SCHWAB, HSI-YANG WU, HEATHER SELMAN, GRAHAME H.H. SMITH, HOWARD M. SNYDER, and DOUGLAS A. CANNING SCHWABC. SCHWAB , WUHSI-YANG WU SELMANHEATHER SELMAN SMITHGRAHAME SMITH SNYDERHOWARD SNYDER CANNINGDOUGLAS View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64225-5AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack...

10.1016/s0022-5347(05)64225-5 article EN The Journal of Urology 2002-12-01

No AccessJournal of UrologyPediatric Urology1 Apr 1998SURGICAL MANAGEMENT OF THE NONPALPABLE TESTIS: CHILDREN'S HOSPITAL PHILADELPHIA EXPERIENCE ANDREW J. KIRSCH, JOSE ESCALA, JOHN W. DUCKETT, GRAHAME H.H. SMITH, STEPHEN A. ZDERIC, DOUGLAS CANNING, and HOWARD M. SNYDER KIRSCHANDREW KIRSCH More articles by this author , ESCALAJOSE ESCALA DUCKETTJOHN DUCKETT (Duckett) Deceased. SMITHGRAHAME SMITH ZDERICSTEPHEN ZDERIC CANNINGDOUGLAS CANNING SNYDERHOWARD View All Author...

10.1016/s0022-5347(01)63613-9 article EN The Journal of Urology 1998-04-01

Testicular teratoma is a rare neoplasm affecting the pediatric population and has classically been reported to be second most common testis tumor in children behind yolk sac tumors. teratomas are benign partial orchiectomy may considered. We describe our single institution experience with testicular definitive treatment preserving surgery.We reviewed pathology records at for all paratesticular tumors diagnosed between 1976 November 2002 males younger than 18 years. specifically examined...

10.1097/01.ju.0000101185.90327.b4 article EN The Journal of Urology 2004-01-01

A high rate of spontaneous resolution or decrease in urinary tract dilatation is expected for most cases primary megaureter (PM). We analyzed our results with extended long-term nonsurgical treatment a group children diagnosed prenatally detected PM. also sought to determine the safety this approach and clinical significance residual hydroureteronephrosis (HUN) when complete does not occur.We reviewed experience 40 infants hydronephrosis as PM who were initially treated nonoperatively...

10.1097/01.ju.0000152319.72909.52 article EN The Journal of Urology 2005-03-02

Our goal is to determine if antimicrobial prophylaxis with trimethoprim/sulfamethoxazole prevents recurrent urinary tract infections and renal scarring in children who are found have vesicoureteral reflux after a first or second infection.The Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR) study double-blind, randomized, placebo-controlled trial. Six hundred aged 2 72 months will be recruited from both primary subspecialty care settings at clinical trial centers...

10.1542/peds.2008-1285d article EN PEDIATRICS 2008-11-18

We assessed the testicular growth of adolescent males followed nonsurgically for presence left varicocele.We retrospectively reviewed charts with a diagnosis unilateral varicocele and ultrasound testis volume measurements seen during 10-year period. A total 161 boys underwent at least 2 ultrasounds as part evaluation varicocele. Patients were excluded from study history inguinal/scrotal pathology or endocrinopathy that could affect size. Sonographic was calculated using Lambert (length x...

10.1016/j.juro.2008.05.061 article EN The Journal of Urology 2008-07-19

Accepted management of vesicoureteral reflux includes surgical correction or prophylactic antibiotics with the hope for resolution as child grows. The physician must consider surgery when does not resolve despite uneventful years on antibiotics. An alternative is cessation We report outcome children taken off persistent reflux.During a 14-year period 51 documented were antibiotic prophylaxis. Selection criteria included who old enough to verbalize symptoms urinary tract infection, and had...

10.1016/s0022-5347(05)68034-2 article EN The Journal of Urology 2000-01-01

No AccessJournal of UrologyPediatric Urology: Editorial1 Apr 1997Testis Sparing Surgery for Steroid Unresponsive Testicular Tumors the Adrenogenital Syndrome Brady R. Walker, Steven J. Skoog, Boyd H. Winslow, Douglas A. Canning, and Edward S. Tank WalkerBrady Walker , SkoogSteven Skoog WinslowBoyd Winslow CanningDouglas Canning TankEdward View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)65023-7AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack...

10.1016/s0022-5347(01)65023-7 article EN The Journal of Urology 1997-04-01

No AccessJournal of Urology1 Jan 1991Endoscopic Injection Glutaraldehyde Cross-Linked Bovine Dermal Collagen for Correction Vesicoureteral Reflux Michael P. Leonard, Douglas A. Canning, Craig Peters, John Gearhart, and Robert D. Jeffs LeonardMichael Leonard More articles by this author , CanningDouglas Canning Current address: Balboa Naval Hospital, San Diego, California 92134. PetersCraig Peters Boston Children’s Boston, Massachusetts 02115. GearhartJohn Gearhart JeffsRobert View All Author...

10.1016/s0022-5347(17)38264-2 article EN The Journal of Urology 1991-01-01

Nonoperative management of radiographically defined solid organ injuries has proven highly successful in children with blunt splenic and hepatic injuries. The role nonoperative protocols is less well for renal purpose this study was to review the outcome a consecutive series injury.The trauma registry from Level I pediatric center reviewed identify all (age < 19 years) who were treated injury period January 1995 through December 2002. Demographic, anatomic, physiologic, management, data...

10.1097/01.ta.0000141022.01878.c2 article EN Journal of Trauma and Acute Care Surgery 2004-09-01

Several studies have anecdotally reported the occurrence of altered urinary voiding patterns in rodents exposed to social stress. A recent study characterized urodynamic and central changes a rat model defeat. Here, we describe similar phenotype induced mice by stress addition potential molecular mechanisms underlying resulting bladder wall remodeling. The mechanism leading habits may be relevant human syndrome dysfunctional which is thought psychological component. To better characterize...

10.1152/ajprenal.90749.2008 article EN AJP Renal Physiology 2009-07-09

Approximately 20% of boys with posterior urethral valves develop ESRD; however, few factors associated the risk ESRD have been identified. The objective this study was to determine if renal parenchymal area, defined as area kidney minus pelvicaliceal system on first postnatal ultrasound, is in infants valves.A retrospective cohort who were diagnosed at less than 6 months age between 1988 and 2011 followed for least 1 year a free-standing children's hospital assembled. Cox proportional hazard...

10.2215/cjn.08700813 article EN Clinical Journal of the American Society of Nephrology 2013-12-06

No AccessJournal of UrologyPediatric Urology1 Aug 2020Time to Complication Detection after Primary Pediatric Hypospadias Repair: A Large, Single Center, Retrospective Cohort AnalysisThis article is commented on by the following:Editorial Comment Jacob Lucas, Tyler Hightower, Dana A. Weiss, Jason Van Batavia, Simmona Coelho, Arun K. Srinivasan, Aseem R. Shukla, Steven Zderic, Thomas F. Kolon, Mark Zaontz, Douglas Canning, and Christopher J. Long LucasJacob Lucas Department Urology, Einstein...

10.1097/ju.0000000000000762 article EN The Journal of Urology 2020-01-23

No AccessJournal of UrologyPEDIATRIC UROLOGY1 Dec 2002The Ascending Testis and the Undescended Since Birth Share Same Histopathology SUSAN L. RUSNACK, HSI-YANG WU, DALE S. HUFF, HOWARD M. SNYDER, STEPHEN A. ZDERIC, MICHAEL C. CARR, DOUGLAS CANNING RUSNACKSUSAN RUSNACK More articles by this author , WUHSI-YANG WU HUFFDALE HUFF SNYDERHOWARD SNYDER ZDERICSTEPHEN ZDERIC CARRMICHAEL CARR CANNINGDOUGLAS View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64223-1AboutFull TextPDF...

10.1016/s0022-5347(05)64223-1 article EN The Journal of Urology 2002-12-01
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