A5041249851- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Spinal Dysraphism and Malformations
- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Dialysis and Renal Disease Management
- Renal and related cancers
- Ureteral procedures and complications
- Hernia repair and management
- Healthcare Policy and Management
- Childhood Cancer Survivors' Quality of Life
- Pelvic floor disorders treatments
- Male Reproductive Health Studies
- Enhanced Recovery After Surgery
- Diversity and Career in Medicine
- Renal cell carcinoma treatment
- Sexual Differentiation and Disorders
- Urinary Tract Infections Management
- Sperm and Testicular Function
- Chronic Kidney Disease and Diabetes
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Prostate Cancer Treatment and Research
- Global Cancer Incidence and Screening
Lurie Children's Hospital
2018-2025
John T. Mather Memorial Hospital
2025
Fleet Science Center
2024
Avidity (United States)
2024
Northwestern University
2018-2023
Vanderbilt University Medical Center
2023
University of Alabama in Huntsville
2023
Comer Children's Hospital
2023
Hospital Nacional de Niños
2023
Northwestern Medicine
2023
Background and objectives The prevalence of nephrolithiasis in the United States has increased substantially, but recent changes incidence with respect to age, sex, race are not well characterized. This study examined temporal trends annual cumulative risk among children adults living South Carolina over a 16-year period. Design, setting, participants, & measurements We performed population–based, repeated cross–sectional using US Census Medical Encounter data, which capture all emergency...
Results following distal hypospadias repair are favorable. Grouping proximal and artificially increases the perceived success rate of hypospadias. We identified our complication hypothesized a higher for 1-stage repair.We retrospectively reviewed records consecutive boys who underwent from 2007 to 2014. Proximal was defined as urethral meatus location at or more than penoscrotal junction after penile degloving. further stratified into those with planned vs 2-stage repair. Univariate Cox...
Renal ultrasounds are performed in patients with myelomeningocele to screen for markers of kidney health, including hydronephrosis. We evaluated the diagnostic accuracy hydronephrosis low function defined by estimated glomerular filtration rate (eGFR). a retrospective cross-sectional study using data from 2 cohorts children and youth myelomeningocele. The first cohort is Urological Management Preserve Initial Function Protocol Young Children With Spina Bifida (UMPIRE; 2016-2022) second...
Leukocytosis, defined as an elevated white blood cell (WBC) count, can arise from physiological, infectious, neoplastic, or medication-related causes. While leukocytosis has been well-documented in conditions such infections and malignancies, drug-induced is relatively rare, particularly individuals undergoing gender transition therapies. Medroxyprogesterone, a progestin used both fertility treatments gender-affirming care, associated with hematologic changes, though its role sustained...
Abstract BACKGROUND: The impact of race and socioeconomic status (SES) in prostate cancer (CaP) outcomes has been well‐studied, but controversy remains. associations race/SES with intermediate CaP outcomes, including positive surgical margin (PSM) biochemical recurrence (BCR), were explored an equal‐access setting. METHODS: Data retrospectively collected from 2502 men the Shared Equal Access Regional Cancer Hospitals (SEARCH) database who underwent radical prostatectomy 1989 to 2010. SES...
Nephron sparing surgery is the standard of care for many adults with renal tumors and has been described in some children Wilms tumor. However, beyond case series data concerning nephron application outcomes patients tumor are scarce. We examined factors associated its tumor.We retrospectively reviewed 1998 to 2010 SEER database. identified 18 years old or younger Clinical, demographic socioeconomic were abstracted, statistical analysis was performed using multivariate logistic regression...
BACKGROUND AND OBJECTIVE: Quality improvement in surgery involves identifying patients at high risk for postoperative complications. We sought to assess the impact of race and procedure type on 30-day surgical morbidity pediatric urology. METHODS: The National Surgical Improvement Program–Pediatrics (NSQIP-P) is a prospective registry cases from 50 56 hospitals 2012 2013, respectively. performed cohort study children followed NSQIP-P who underwent urologic surgery. Forty unique operations...
Antibody–oligonucleotide conjugates are a promising class of therapeutics for extrahepatic delivery small interfering ribonucleic acids (siRNAs). These can be optimized improved and mRNA knockdown (KD) through understanding structure–activity relationships. In this study, we systematically examined factors including antibody isotype, siRNA chemistry, linkers, conjugation PEGylation, drug-to-antibody ratios (DARs) their impact on bioconjugation, pharmacokinetics (PK), delivery, bioactivity....
<h3>Importance</h3> Health literacy has been shown to play an important role in transitions of care adult populations, with low health associated adverse outcomes. The the transition from pediatric less well studied. Among adolescents and young adults spina bifida, high rates unsuccessful have shown, but how patient affects readiness remains unknown. <h3>Objective</h3> To determine whether is bifida. <h3>Design, Setting, Participants</h3> This cross-sectional study involved collection...
The strength of the evidence base for comparative effectiveness three common surgical modalities paediatric nephrolithiasis (ureteroscopy, shockwave lithotripsy and percutaneous nephrolithotomy) its relevance to patients caregivers are insufficient. We describe methods rationale Pediatric KIDney Stone (PKIDS) Care Improvement Network Trial with aim compare in based on stone clearance lived patient experiences. This protocol serves as a patient-centred alternative randomised controlled trials...
Aims Current estimated glomerular filtration rate (eGFR) equations may be inaccurate in patients with spina bifida (SB) because of reduced muscle mass and stature. Cross‐sectional longitudinal variability eGFR were analyzed these across multiple equations, hypothesizing greater creatinine‐based than cystatin‐C (Cys‐C)‐based equations. Methods This retrospective cohort study included children (age, 1‐17.9 years) adults (≥18 SB from 2002‐2017 at a large clinic. Those without all data needed to...
Introduction Lower urinary tract reconstruction in paediatric urology represents a physiologically stressful event that is associated with high complication rates, including readmissions and emergency room visits. Enhanced recovery after surgery (ERAS) protocol set of multidisciplinary, perioperative strategies designed to expedite surgical without adversely impacting readmission or reoperation rates. Early data demonstrated ERAS reduced complications this population. Methods analysis In...
We sought to assess associations between health-related quality of life (QOL), bladder-related QOL, bladder symptoms, and catheterization route among adolescents young adults with spina bifida.