A5061238073- Renal cell carcinoma treatment
- Renal and related cancers
- MRI in cancer diagnosis
- Renal and Vascular Pathologies
- Genetic and Kidney Cyst Diseases
- Pediatric Urology and Nephrology Studies
- Technology and Data Analysis
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- bioluminescence and chemiluminescence research
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Treatment and Research
- Computational Drug Discovery Methods
- Health and Medical Research Impacts
- Chronic Kidney Disease and Diabetes
- Spinal Fractures and Fixation Techniques
- MicroRNA in disease regulation
- Diversity and Career in Medicine
- Innovations in Medical Education
- Neuroinflammation and Neurodegeneration Mechanisms
- Abdominal Trauma and Injuries
- Tissue Engineering and Regenerative Medicine
- Biochemical effects in animals
- Cell Image Analysis Techniques
- thermodynamics and calorimetric analyses
National Institutes of Health
2022-2025
National Cancer Institute
2022-2025
UConn Health
2018-2025
University of Connecticut
2019-2024
Center for Cancer Research
2022-2024
National Institutes of Health Clinical Center
2023
Children's Hospital of Philadelphia
2023
National Center for Advancing Translational Sciences
2022
The presence of an artificial urinary sphincter can be overlooked resulting in inadvertent urethral catheterization and cuff erosion. A hard-stop best practice advisory was created the electronic medical record to alert for sphincter. We evaluated its utilization impact on patient outcomes. Our fired men with implanted or place between August 1, 2016, September 30, 2023. calculated exposure years (total time implant duration during each period), which were used determine incidence rates...
Results from prior studies show contradictory evidence in determining whether utilization of renal ischemia during partial nephrectomies (PN) results worse functional outcomes. Data assessing a large cohort patients with no PN are lacking. The purpose this study was to evaluate the use and type affects A retrospective review 742 undergoing were assessed split into 4 cohorts: (n = 455), cold 63), warm time (WIT) < 30 minutes 164), WIT ≥ 60). Twelve-month relative glomerular filtration rate...
Determining a molecule's mechanism of action is paramount during chemical probe development and drug discovery. The cellular thermal shift assay (CETSA) valuable tool to confirm target engagement in cells for small molecule that demonstrates pharmacological effect. CETSA directly detects biophysical interactions between ligands protein targets, which can alter protein's unfolding aggregation properties response challenge. In traditional experiments, each temperature requires an individual...
Abstract Lower urinary tract dysfunction (LUTD) increases with aging. Ensuing symptoms including incontinence greatly impact quality of life, isolation, depression, and nursing home admission. The aging bladder is hypothesized to be central this decline, however, it remains difficult pinpoint a singular strong driver aging‐related dysfunction. Many molecular cellular changes occur aging, contributing decreased resilience internal external stressors, affecting control exacerbating LUTD. In...
You have accessJournal of UrologyCME1 Apr 2023MP18-20 AUTOMATED URINARY TRACT DILATION GRADING OF HYDRONEPHROSIS ON ULTRASOUND IMAGING USING A CONVOLUTIONAL NEURAL NETWORK David Ostrowski, Joseph Logan, Maria Antony, Reilly Broms, Dana Weiss, Jason van Batavia, Christopher Long, Ariana Smith, Stephen Zderic, Rebecca Edwins, Raymond Pominville, Jessica Hannick, Lynn Woo, Yong Fan, Gregory Tasian, and John Weaver OstrowskiDavid Ostrowski More articles by this author , LoganJoseph Logan...
The von Hippel-Lindau disease (VHL) is a hereditary cancer syndrome with multifocal, bilateral cysts and solid tumors of the kidney. Surgical management may include multiple extirpative surgeries, which ultimately results in parenchymal volume loss subsequent renal function decline. Recent studies have utilized parenchyma as an estimate prior to surgery for cell carcinoma; however, it not yet validated surgically altered kidneys multifocal masses complex such are present VHL.We sought...
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Male Incontinence (MP03)1 May 2024MP03-05 DEVELOPMENT, IMPLEMENTATION, AND IMPACT OF AN ELECTRONIC MEDICAL RECORD ALERT SYSTEM FOR IMPLANTED ARTIFICIAL URINARY SPHINCTERS Dylan Buller, Philip Olson, Maria Antony, Jennifer Lindelof, Ilene Staff, Tara McLaughlin, Joseph Tortora, Kevin Pinto, Laura Olivo Valentin, Fadi Hammami, Jared Bieniek, and Richard Kershen BullerDylan Buller , OlsonPhilip...
Reoperative partial nephrectomy (RePN) offers several advantages for the treatment of recurrent, multifocal renal masses. RePN has been previously demonstrated to be technically feasible and delay need replacement therapy. However, there is still inherent complexity known risks reoperative nephrectomy. We studied largest population RePNs characterize functional outcomes likelihood intra- postoperative complications.
You have accessJournal of UrologyCME1 Apr 2023PD06-12 INTER- AND INTRA-RATER VARIABILITY OF VIDEOURODYNAMIC STUDY INTERPRETATION AMONG UROLOGIC SURGEONS FOR PATIENTS WITH SPINA BIFIDA Maria Antony, John K. Weaver, Madalyne Martin-Olenski, Joseph Logan, Reiley Broms, David Ostrowski, Jason Van Batavia, Dana A. Weiss, Christopher J. Long, Ariana L. Smith, Jing Huang, Stephen Zderic, Yong Fan, and Gregory E. Tasian AntonyMaria Antony More articles by this author , WeaverJohn Weaver...
You have accessJournal of UrologyCME1 Apr 2023PD40-07 CUMULATIVE IMPACT OF REOPERATIVE PARTIAL NEPHRECTOMY FOR THE TREATMENT RECURRENT RENAL MASSES Maria Antony, Zach Kozel, Nikhil Gopal, Lauren Loebach, Julie Solomon, Adam Metwalli, Sandeep Gurram, W. Marston Linehan, and Mark Ball AntonyMaria Antony More articles by this author , KozelZach Kozel GopalNikhil Gopal LoebachLauren Loebach SolomonJulie Solomon MetwalliAdam Metwalli GurramSandeep Gurram LinehanW. Linehan BallMark View All Author...
You have accessJournal of UrologyCME1 Apr 2023MP31-06 SURVIVAL BENEFIT OF RENAL TRANSPLANTATION FOLLOWING COMPLETION NEPHRECTOMY IN VON HIPPEL LINDAU DISEASE Maria Antony, Alexis Rompré-Brodeur, Aditi Chaurasia, Nikhil Gopal, Zach Kozel, Julie Solomon, Lauren Loebach, Sandeep Gurram, W. Marston Linehan, and Mark Ball AntonyMaria Antony More articles by this author , Rompré-BrodeurAlexis Rompré-Brodeur ChaurasiaAditi Chaurasia GopalNikhil Gopal KozelZach Kozel SolomonJulie Solomon...
Introduction: MicroRNAs (miRNAs) are a class of short non-coding RNAs. Dysregulation variety miRNAs have been tied to several neurological disorders including stroke. Recent studies also found that microRNA profiles can change as result social environments. We previously shown the isolation is detrimental post-stroke recovery. MiR 181c-family miRNA one evolutionarily conserved and highly expressed family in brain. Therefore, this study we examined specific role miR-181c-5p after isolation....
Abstract Determining a molecule’s mechanism of action is paramount during chemical probe development and drug discovery. The cellular thermal shift assay (CETSA) valuable tool to confirm target engagement in cells for small molecule that demonstrates pharmacological effect. CETSA directly detects biophysical interactions between ligands protein targets, which can alter protein’s unfolding aggregation properties response challenge. In traditional experiments, each temperature requires an...
You have accessJournal of UrologyCME1 May 2022PD18-07 PERFORMANCE OF GFR CALCULATORS: CKD-EPI 2021, 2009, AND MDRD IN ESTIMATION KIDNEY FUNCTION PRIOR TO NEPHRECTOMY Maria Antony, Aditi Chaurasia, Nikhil Gopal, Pouria Yazdian, Zach Kozel, Sandeep Gurram, Marston Linehan, and Mark Ball AntonyMaria Antony More articles by this author , ChaurasiaAditi Chaurasia GopalNikhil Gopal YazdianPouria Yazdian KozelZach Kozel GurramSandeep Gurram LinehanMarston Linehan BallMark View All Author...