Amir H. Lebastchi

ORCID: 0000-0002-1441-2132
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About
Contact & Profiles
Research Areas
  • Renal cell carcinoma treatment
  • Renal and related cancers
  • Prostate Cancer Diagnosis and Treatment
  • Bladder and Urothelial Cancer Treatments
  • Diversity and Career in Medicine
  • Prostate Cancer Treatment and Research
  • Parathyroid Disorders and Treatments
  • Thyroid and Parathyroid Surgery
  • Organ Donation and Transplantation
  • Urological Disorders and Treatments
  • Surgical Simulation and Training
  • Urinary and Genital Oncology Studies
  • Hospital Admissions and Outcomes
  • Hernia repair and management
  • Adrenal and Paraganglionic Tumors
  • Renal and Vascular Pathologies
  • Pediatric Urology and Nephrology Studies
  • Global Health Workforce Issues
  • Intestinal Malrotation and Obstruction Disorders
  • Pituitary Gland Disorders and Treatments
  • Genetic Syndromes and Imprinting
  • Multiple and Secondary Primary Cancers
  • T-cell and B-cell Immunology
  • Intestinal and Peritoneal Adhesions
  • Testicular diseases and treatments

National Institutes of Health
2020-2025

National Cancer Institute
2020-2025

University of Southern California
2022

University of Michigan
2016-2020

Ann Arbor Center for Independent Living
2016-2019

Iowa City Public Library
2019

Giorgio Cini Foundation
2019

Canadian Urological Association
2019

Michigan Medicine
2018

Urology of Indiana
2017

Type 1 diabetes (T1D) results from immune-mediated destruction of insulin-producing β-cells. The killing β-cells is not currently measurable; β-cell functional studies routinely used are affected by environmental factors such as glucose and cannot distinguish death dysfunction. Moreover, it known whether immune therapies affect killing. We developed an assay to identify measuring relative levels unmethylated INS DNA in serum measure a clinical trial teplizumab. studied 43 patients with...

10.2337/db12-1207 article EN cc-by-nc-nd Diabetes 2013-02-20

Abstract Perioperative injuries to an allograft exacerbate graft rejection, which in humans is primarily mediated by effector memory T cells. IL-6 transcripts human coronary artery segments rapidly increase posttransplantation into immunodeficient mouse hosts compared with those of pretransplant specimens and fall dramatically 30 d. Adoptive transfer PBMCs allogeneic the 2 d postoperatively results cell infiltrates intimal expansion 4 wk later. Ab neutralization reduces magnitude total...

10.4049/jimmunol.1003774 article EN The Journal of Immunology 2011-11-15

Results from prior studies show contradictory evidence in determining whether utilization of renal ischemia during partial nephrectomies (PN) results worse functional outcomes. Data assessing a large cohort patients with no PN are lacking. The purpose this study was to evaluate the use and type affects A retrospective review 742 undergoing were assessed split into 4 cohorts: (n = 455), cold 63), warm time (WIT) < 30 minutes 164), WIT ≥ 60). Twelve-month relative glomerular filtration rate...

10.1097/upj.0000000000000779 article EN Urology Practice 2025-02-04

Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy that generally conveys poor prognosis. Currently, surgical resection considered the lone curative treatment modality. In addition, low prevalence of ACC has limited effective clinical trial design to develop evidence-based approaches therapy. The proper role radio- and chemotherapy for still being defined. Similarly, molecular pathogenesis remains be fully characterized. Despite these challenges, progress been made in several...

10.1155/2012/234726 article EN cc-by Journal of Oncology 2012-01-01

10.1016/j.jtcvs.2014.03.040 article EN publisher-specific-oa Journal of Thoracic and Cardiovascular Surgery 2014-03-27

Abstract Atherosclerosis of native coronary arteries and graft arteriosclerosis in transplanted hearts are characterized by activation innate adaptive immune responses. Nucleic acids generated infections or cell death have been detected within arteriosclerotic lesions, it is known that microbial synthetic nucleic evoke inflammatory responses cultured vascular cells. In this study, we report model RNA, but not DNA, instigated robust cytokine chemokine production from intact human containing...

10.4049/jimmunol.0902283 article EN The Journal of Immunology 2010-06-21

You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy V1 Apr 2017MP72-06 MULTI-INSTITUTIONAL SURVIVAL ANALYSIS OF INCIDENTAL PATHOLOGIC T3A UPSTAGING IN CLINICAL T1 RENAL CELL CARCINOMA FOLLOWING PARTIAL NEPHRECTOMY Christopher M. Russell, Amir H. Lebastchi, Juan Chipollini, Adam Niemann, Rohit Mehra, Todd Morgan, David C. Miller, Ganesh S. Palapattu, Khaled Hafez, J. Stuart Wolf, Wade Sexton, Philippe E. Spiess, and Alon Z. Weizer RussellChristopher Russell More...

10.1016/j.juro.2017.02.2242 article EN The Journal of Urology 2017-04-01

We aimed to assess post-interventional and 36-month follow-up results of a single-center, single-arm, in-bore phase I trial focal laser ablation (FLA) guided by multiparametric magnetic resonance imaging (mpMRI).

10.5152/dir.2021.20095 article EN Diagnostic and Interventional Radiology 2021-04-22

Locoregional anesthesia, conscious sedation, and exploration via a limited incision have become well-accepted approach for the treatment of patients with primary hyperparathyroidism image-localized, presumed single-gland disease. However, to our knowledge, this minimally invasive technique has never been investigated in multigland disease.To extrapolate locoregional perform bilateral who hyperplasia.Retrospective analysis at tertiary academic referral center 100 consecutive undergoing...

10.1001/jamasurg.2014.1296 article EN JAMA Surgery 2014-09-04
Sriram Deivasigamani Ardeshir R. Rastinehad Laurence Klotz Herbert Lepor Hashim U. Ahmed and 95 more Peter A. Pinto Samir S. Taneja Mark Emberton Inderbir S. Gill Hendrik Van Poppel Julio Paw Sang Kae Jack Tay Taimur T. Shah Giancarlo Marra Lara Rodríguez‐Sánchez Mahdi Mottaghi Srinath Kotamarti James Wysock John F. Feller Praveen Kumar Rajan T. Gupta Francesco Giganti Andre Luis Abreu Arjun Sivaraman Michael B. Rothberg Osamu Ukimura John F. Ward Theo M.de Reijke Boris Hadaschik Nikos I. Mertziotis Aaron Katz Paolo Gontero Bryan Donnelly Phillip D. Stricker Joseph L. Chin Nathan Lawrentschuk Katsuto Shinohara Cary N. Robertson Ardalan E. Ahmad Amir H. Lebastchi Sébastien Crouzet Arnauld Villers Barış Bakır Craig Rogers Jurgen J. Fütterer Adam Kinnaird Xavier Cathelineau Armando Stabile Frans MJ Debfruyne Paul J.M. Kil Erik B. Cornel Eduard Baco Rubén Olivares Petr Macek Courtney K. Phillips Michael J. Schwartz Peter KF Chiu Soroush Rais Bahrami Daniel Margolis Timothy McClure Massimo Valério Veeru Kasivisvanathan Jochen Walz Derek J. Lomas Mohummed Minhaj Siddiqui Wei Phin Tan Eric S. Adams Denis Séguier Gustavo Cardoso Guimarães Alireza Aminsharifi Ezequiel Becher Antonio Finelli Ali Kasraeian Hao G. Nguyen Michael A. Gorin Thomas Frye Rohit Arcot Yamini Nagaraj Samuel W. Yee Christopher Netsch Celi Varol Xiaosong Meng Stefano Regusci Tavya G. R. Benjamin Alessandro Marquis Fernando J. Bianco Fernando J. Kim Robert Given Sunao Shoji Kian Tai Chong Rafael Tourinho‐Barbosa Randall Lee Ariel Schulmann Jeremy Grummet Stephen Scionti Georg Salomon Pilar Laguna Srinivas Vourganti Wayne Brisbane Deepika Reddy

10.2139/ssrn.4981096 preprint EN 2024-01-01

You have accessJournal of UrologyProstate Cancer: Detection & Screening II1 Apr 2017PD07-03 MICHIGAN PROSTATE SCORE (MIPS): AN ANALYSIS OF A NOVEL URINARY BIOMARKER PANEL FOR THE PREDICTION CANCER AND ITS IMPACT ON BIOPSY RATES Amir H. Lebastchi, Christopher M. Russell, Alexander Helfand, Takahiro Osawa, Javed Siddiqui, Rabia Arul Chinnaiyan, Priya Kunju, Rohit Mehra, Debbie Snyder, Scott A. Tomlins, Jont T. Wei, and Todd Morgan LebastchiAmir Lebastchi More articles by this author ,...

10.1016/j.juro.2017.02.378 article EN The Journal of Urology 2017-04-01
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