A5056148509- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Renal and related cancers
- MRI in cancer diagnosis
- Renal and Vascular Pathologies
- Urologic and reproductive health conditions
- Pediatric Urology and Nephrology Studies
- Radiomics and Machine Learning in Medical Imaging
- Urological Disorders and Treatments
- Minimally Invasive Surgical Techniques
- Nanoplatforms for cancer theranostics
- Cancer Genomics and Diagnostics
- Urinary and Genital Oncology Studies
- Photodynamic Therapy Research Studies
- Cancer, Hypoxia, and Metabolism
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Adrenal and Paraganglionic Tumors
- Economic and Financial Impacts of Cancer
- Ureteral procedures and complications
- Health Systems, Economic Evaluations, Quality of Life
Rush University Medical Center
2016-2025
Rush University
2022-2024
SUNY Upstate Medical University
2013-2018
Albany Medical Center Hospital
2018
National Cancer Institute
2011-2017
Center for Cancer Research
2011-2017
National Institutes of Health
2011-2015
National Institutes of Health Clinical Center
2014
ABT Molecular Imaging (United States)
2014
Emory University
2013
Patients with negative transrectal ultrasound biopsies and a persistent clinical suspicion are at risk for occult but significant prostate cancer. The ability of multiparametric magnetic resonance imaging/ultrasound fusion biopsy to detect these lesions may make it an effective tool in this challenging scenario.
BACKGROUND Active surveillance (AS) is an attempt to avoid overtreatment of clinically insignificant prostate cancer (PCa); however, patient selection remains controversial. Multiparametric magnetic resonance imaging (MP‐MRI) may help better select AS candidates. METHODS We reviewed a cohort men who underwent MP‐MRI with MRI/Ultrasound fusion–guided biopsy and selected potential patients at entry using Johns Hopkins criteria. findings were assessed, including number lesions, dominant lesion...
No AccessJournal of UrologyAdult Urology1 Nov 2013Utility Multiparametric Magnetic Resonance Imaging Suspicion Levels for Detecting Prostate Cancer Soroush Rais-Bahrami, M. Minhaj Siddiqui, Baris Turkbey, Lambros Stamatakis, Jennifer Logan, Anthony N. Hoang, Annerleim Walton-Diaz, Srinivas Vourganti, Hong Truong, Jochen Kruecker, Maria J. Merino, Bradford Wood, Peter L. Choyke, and A. Pinto Rais-BahramiSoroush Rais-Bahrami Urologic Oncology Branch, National Institute, Institutes Health,...
Purpose Approximately 5% to 8% of renal cell carcinoma (RCC) is hereditary. No guidelines exist for patient selection RCC germline mutation testing. We evaluate how age onset could indicate the need testing detection inherited forms kidney cancer. Patients and Methods analyzed distribution cases in SEER-17 program our institutional hereditary cancer population. The distributions were compared by sex, race, histology, syndrome. Models established specific thresholds genetic Results median...
Objectives To determine the diagnostic yield of analysing biparametric ( T 2‐ and diffusion‐weighted) magnetic resonance imaging B ‐ MRI ) for prostate cancer detection compared with standard digital rectal examination DRE prostate‐specific antigen PSA )‐based screening. Patients Methods Review patients who were enrolled in a trial to undergo multiparametric‐prostate MP )‐ MR /ultrasound fusion‐guided biopsy at our institution identified 143 men underwent MP‐MRI addition ‐based screening...
There are few published studies prospectively assessing pharmacological interventions that may delay prostate cancer progression in patients undergoing active surveillance (AS).
We sought to analyze temporal trends in the utilization of minimally invasive vs open adrenalectomy United States; assess costs, perioperative outcomes, and determining factors influencing these variables.
Study Type – Diagnostic (case series) Level of Evidence 4 What's known on the subject? and What does study add? Over‐treatment indolent prostate cancer lesions is a problem which can result in increased human medical costs. Lesions with low suspician level at mpMRI have risk including high cancer. Objective To determine whether multiparametric magnetic resonance imaging ( ) has potential to identify patients for cancer, thus obviating need biopsy. Prostate currently diagnosed by random...
BACKGROUND Partial nephrectomy (PN) and radical (RN) are standard treatments for a small renal mass. Retrospective studies suggest an overall survival (OS) advantage, however randomized phase 3 trial suggests otherwise. The effects of both surgical modalities on OS were evaluated compared with controls. METHODS A matched cohort study was performed using the Surveillance, Epidemiology, End Results (SEER)‐Medicare dataset. Individuals treated PN or RN localized cell carcinoma (RCC) measuring...
Study Type - Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does study add? Sarcomatoid renal cell carcinoma can occur in setting all histological subtypes kidney cancer. These tumours are very aggressive many patients present with disseminated disease. Long-term survival is poor durable responses to systemic therapy infrequent. Our large cohort analyses influence pathological tumour characteristics determining prognosis for sarcomatoid undergoing surgical...
Patients with an enlarged prostate and suspicion of cancer pose a diagnostic dilemma. The detection rate systematic 12-core transrectal ultrasound guided biopsy is between 30% 40%. For prostates greater than 40 cc this decreases to or less. Magnetic resonance-ultrasound fusion has shown superior rates. We defined the magnetic in men gland.We retrospectively analyzed records patients who underwent multiparametric resonance imaging followed by at our institution. Whole volumes were calculated...
The use of light as a means therapy for bladder cancer has long history but been hampered by lack tumor specificity and therefore, damage to the normal mucosa. Here, we describe targeted form phototherapy called photoimmunotherapy (PIT), which targets EGFR-expressing cancer. Anti-EGFR antibody panitumumab was labeled with photoabsorber (PA), IRDye 700Dx (IR700), create panitumumab-IR700 antibody-PA conjugate that is activated near-infrared radiation (NIR). Bladder tissue microarray (TMA)...
Background Most Prostate Imaging–Reporting and Data System (PI‐RADS) 3 lesions do not contain clinically significant prostate cancer (CSPCa; grade group ≥2). This study was aimed at identifying clinical magnetic resonance imaging (MRI)–derived risk fac‐ tors that predict CSPCa in men with PI‐RADS lesions. Methods analyzed the detection of who underwent MRI‐targeted biopsy for Multivariable logistic regression models goodness‐of‐fit testing were used to identify variables associated CSPCa....
PURPOSEWe aimed to determine the natural history of small index lesions identified on multiparametric-magnetic resonance imaging (MP-MRI) prostate by evaluating lesion-specific pathology and growth serial MP-MRI. MATERIALS AND METHODSWe performed a retrospective review 153 patients who underwent minimum two MP-MRI sessions, an institutional board-approved protocol.Index lesion is defined as lesion(s) with highest cancer suspicion score based initial patient, irrespective size.Two study...
Partial and radical nephrectomy are treatments for the small renal mass. is considered gold standard as it may protect against dysfunction compared to nephrectomy. However, both cause adverse health outcomes.A matched cohort study was performed using SEER (Surveillance, Epidemiology End Results)-Medicare data set. Individuals treated with partial or 4 cm smaller nonmetastatic cell carcinoma were 2 control groups (nonmuscle invasive bladder cancer noncancer). A greedy algorithm surgical...
Study Type – Diagnosis (case series) Level of Evidence 4 What's known on the subject? and What does study add? Benign prostatic hyperplasia is most common symptomatic disorder prostate its severity varies greatly in population. Various methods have been used to estimate volumes past including digital rectal examination ultrasound measurements. High‐resolution T2 weighted MRI can provide accurate measurements zonal total volumes, which be better understand etiology lower urinary tract...
Primary urethral carcinoma (PUC) is rare, accounting for <1% of genitourinary malignancies. Current knowledge regarding founded upon tertiary care centers reporting their experiences. We aim to identify factors predictive outcomes using a nationwide registry database.The Surveillance, Epidemiology, and End Results-18 registries database was queried cases PUC ranging between 2004 2010. To cases, ICD-O site code C68.0 used as filter, hence identifying with histologic subtypes including...