A5070707275- Renal cell carcinoma treatment
- Renal and related cancers
- MRI in cancer diagnosis
- Genetic and Kidney Cyst Diseases
- Renal and Vascular Pathologies
- Bladder and Urothelial Cancer Treatments
- Urological Disorders and Treatments
- Urinary and Genital Oncology Studies
- Radiomics and Machine Learning in Medical Imaging
- Genomics and Phylogenetic Studies
- Ureteral procedures and complications
- Urologic and reproductive health conditions
- Pediatric Urology and Nephrology Studies
- Gene expression and cancer classification
- Bioinformatics and Genomic Networks
- Prostate Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Cancer Genomics and Diagnostics
- Recommender Systems and Techniques
- Chronic Kidney Disease and Diabetes
- Genomics and Rare Diseases
- Renal Transplantation Outcomes and Treatments
- Vascular Procedures and Complications
- Anatomy and Medical Technology
- Mental Health Research Topics
National Cancer Institute
2011-2024
National Institutes of Health
2011-2024
University of Tennessee Health Science Center
2024
Center for Cancer Research
2011-2024
National Institutes of Health Clinical Center
2022-2023
Cancer Institute (WIA)
2022
New York Medical College
2019-2021
Westchester Medical Center
2021
Lincoln Medical Center
2019
University of Washington
2015-2017
Efficient tools for data management and integration are essential many aspects of high-throughput biology. In particular, annotations genes human genetic variants commonly used but highly fragmented across resources. Here, we describe MyGene.info MyVariant.info, high-performance web services querying gene variant annotation information. These currently accessed more than three million times permonth. They also demonstrate a generalizable cloud-based model organizing biological MyVariant.info...
X-linked myotubular myopathy (XLMTM) results from MTM1 gene mutations and myotubularin deficiency. Most XLMTM patients develop severe muscle weakness leading to respiratory failure death, typically within 2 years of age. Our objective was evaluate the efficacy safety systemic therapy in p.N155K canine model by performing a dose escalation study. A recombinant adeno-associated virus serotype 8 (rAAV8) vector expressing (cMTM1) under muscle-specific desmin promoter (rAAV8-cMTM1) administered...
The aim of this study was to assess the interreader reliability and per-RCC sensitivity high-resolution photon-counting computed tomography (PCCT) in detection characterization renal masses comparison MRI.
Introduction and Objective: Scant literature is available on surgical outcomes of radical cystectomies the new single-port (SP) system. This study compares short-term in patients undergoing cystectomy with those intracorporeal urinary diversion (ICUD) multiport (MP) vs SP platform. Methods: institutional review board approved used a prospective database nonparametric testing including chi-squared, Mann-Whitney U, Fisher exact tests to analyze all variables stratified by approach. Results:...
The two primary nephron-sparing interventions for treating renal masses such as cell carcinoma are surgical partial nephrectomy (PN) and image-guided percutaneous thermal ablation. Nephron-sparing surgery, PN, has been the standard of care many localized masses. Although uncommon, complications resulting from PN can range asymptomatic mild to symptomatic life-threatening. These include vascular injuries hematoma, pseudoaneurysm, arteriovenous fistula, and/or ischemia; injury collecting...
Quality of questions and answers from community support websites (e.g. Microsoft Developers Network, Stackoverflow, Github, etc.) is difficult to define a prediction model quality even more challenging implement. Previous works have addressed the question models answer separately using meta-features like number up-votes, trustworthiness person posting or answers, titles post, context naive natural language processing features. However, there lack an integrated question-answer for answering...
Urinary tract leiomyomas are rare, benign mesenchymal tumors that traditionally treated with complete surgical excision. We present three cases of urinary leiomyoma — two located in the bladder and one ureter. Both were transurethral resection tumor (TURBT) no evidence recurrent disease, while upper was managed surveillance by patient preference, which to our knowledge, has not been previously described. The ureteral remained stable at five years followup from initial diagnosis. Given nature...
The von Hippel-Lindau disease (VHL) is a hereditary cancer syndrome with multifocal, bilateral cysts and solid tumors of the kidney. Surgical management may include multiple extirpative surgeries, which ultimately results in parenchymal volume loss subsequent renal function decline. Recent studies have utilized parenchyma as an estimate prior to surgery for cell carcinoma; however, it not yet validated surgically altered kidneys multifocal masses complex such are present VHL.We sought...
ABSTRACT MyGene.info and MyVariant.info provide high-performance data APIs for querying gene variant annotation information. They demonstrate a new model organizing biological information by utilizing cloud-based scalable infrastructure. can be accessed at http://mygene.info http://myvariant.info .
Ureteric duplication is the most common anomaly of urinary system that may be asymptomatic or associated with clinical findings. These cases ureters are found during radiographic imaging abdomen and pelvic region accidentally dissection cadavers. The aim study was to report a congenital in cadaveric dissection. During routine Department Human Biology Faculty Health-Care Sciences, Eastern University, Sri Lanka, we noted left-sided unilateral bifid renal pelvis incompletely duplicated ureter...
Reoperative partial nephrectomy (RePN) offers several advantages for the treatment of recurrent, multifocal renal masses. RePN has been previously demonstrated to be technically feasible and delay need replacement therapy. However, there is still inherent complexity known risks reoperative nephrectomy. We studied largest population RePNs characterize functional outcomes likelihood intra- postoperative complications.