A5100391613- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Additive Manufacturing and 3D Printing Technologies
- Advanced Queuing Theory Analysis
- Cancer Cells and Metastasis
- Innovative Microfluidic and Catalytic Techniques Innovation
- Manufacturing Process and Optimization
- Petri Nets in System Modeling
- Geophysical Methods and Applications
- BIM and Construction Integration
- Welding Techniques and Residual Stresses
- Corneal Surgery and Treatments
- Engineering Applied Research
- Electrospun Nanofibers in Biomedical Applications
- Interconnection Networks and Systems
- Wireless Body Area Networks
- Educational Research and Pedagogy
- Technology and Data Analysis
- Network Traffic and Congestion Control
- Retinal Development and Disorders
- Magnesium Alloys: Properties and Applications
- Single-cell and spatial transcriptomics
- Nerve injury and regeneration
- Breast Implant and Reconstruction
- Cellular Mechanics and Interactions
Pohang University of Science and Technology
1999-2025
Hanyang University
2015
Massachusetts Institute of Technology
2012
Seoul Medical Center
2003
Tissue engineering has emerged as a promising approach to viable small-diameter vascular grafts that may be used treat cardiovascular diseases. One challenge in constructing such blood vessels is proper localization of endothelial cells and smooth muscle cells, well promotion their cellular functions generate functional tissues. Thus far, construction substitutes with both muscular tissues, which essential for the acquire antithrombosis function sufficient strength avoid thrombus formation...
Corneal transplantation is a typical surgical procedure for severe corneal diseases. However, the waiting time donor cornea has gradually increased due to decrease in supply caused by an aging population and cases of laser-based surgeries. Artificial corneas were developed meet increase demand; however, these approaches have suffered from material deterioration resulted limited tissue integration. Here, we introduce cornea-derived decellularized extracellular matrix (Co-dECM) as bioink...
Abstract As the main precursor of cardiovascular diseases, atherosclerosis is a complex inflammatory disorder that preferentially occurs in stenotic, curved, and branched arterial regions. Although various vitro models are established to understand its pathology, reconstructing native atherosclerotic environment involves both co‐cultured cells local turbulent flow singling remains challenging. This study develops an construct via in‐bath coaxial cell printing not only facilitates direct...
Abstract Tissue‐specific decellularized extracellular matrix recapitulates the complexity of natural ECMs, creating an organ‐specific microenvironment based on its intrinsic characteristics. Here, hydrogels containing uterus‐derived (UdECMs) from endometrium‐specific layer or entire uterus are developed. UdECMs serve as effective biomaterials, displaying that intrauterine UdECM administration induces endometrial regeneration and fertility enhancement. Moreover, alters profile killer cell...
Abstract Despite significant research progress, tumor heterogeneity remains elusive, and its complexity poses a barrier to anticancer drug discovery cancer treatment. Response the same varies across patients, timing of treatment is an important factor in determining prognosis. Therefore, development patient‐specific preclinical models that can predict patient's response within short period imperative. In this study, printed gastric (pGC) model developed for chemotherapy using extrusion‐based...
A physiologically relevant tumor microenvironment is favorable for the progression and growth of gastric cancer cells. To simulate tumor-specific conditions in vivo environments, several biomaterials engineering studies have investigated three-dimensional (3D) cultures. However, implementation such cultures remains limited because challenges outlining biochemical biophysical characteristics microenvironment. In this study, we developed a 3D cell printing-based model, using combination...
Abstract Accurate prediction of treatment response for cancer patients is essential overcoming intrinsic therapy resistance that results from genetic heterogeneity, varying tumor growth kinetics, and the complex microenvironment. To achieve this goal, there an urgent need effective preclinical in vitro models recapitulate molecular–pathologic features intricate ecology native tumors precision medicine. In study, a vascularized organoid model (VOM) composed patient‐derived gastric organoids...
Various synthetic and decellularized materials are being used to reconstruct peripheral nerve defects replace autologous grafts. In this study, we developed a microgel printing bath three-dimensionally (3D) print nervous system extracellular matrix graft reinforced by polycaprolactone (PCL) conduit. The straightforward fabrication method of an alginate microgel-supplemented allows 30 μm filament resolution low viscous hydrogel with neutral pH. When applied sciatic defect model rats, the...
본 연구는 BIM을 활용한 그래프 기반의 동선 표현과 분석 접근 방법 제안을 목적으로 한다. 방법의 위해 건물 관련 요구사항 파악과 공간 네트워크, BIM에 관한 선행연구를 분석하였다. 또한, 선행연구인 UCN(Universal Circulation Network)을 기반으로 연구를 진행하였으며, 통해 UCN에 추가적으로 고려해야 할 사항을 파악하고 이를 확장하였다. 연구에서는 UCN을 두 가지 관점에서 동선의 방법을 제안하고자한다: 1) UCN의 기반 분석의 주요 요소를 파악한다, 2) 국내 건축법 등의 요구사항을 적용하여 재구성한다. 결과적으로, 출구에서 가장 먼 점 (MRP) 가상공간에서의 분석이 제안되었다. This paper aims to review and discuss a graph-based approach for the representation analysis of building circulation using BIM models. To propose...
We consider an ATM multiplexer loaded with heterogeneous ON-OFF sources. The is modeled as a discrete-time finite-buffer queueing system. Concentrating on the fact that overload period and succeeding underload form renewal cycle in terms of input process, we develop efficient method for obtaining exact joint steady-state probability distribution both states sources buffer content. Various overall/individual performance measures are derived, such cell loss average delay.
Objectives The purpose of this study is to conduct a comprehensive job analysis entry-level 3D Modeler roles and subsequently develop standardized vocational training program. This program designed meet the needs students pursuing career technical education, with dual cultivating essential skills providing well-defined path. Methods To achieve this, DACUM (Developing Curriculum) workshop was conducted 5 industry experts. outcomes were validated by experts who did not participate in workshop....