A5057375538- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Arrhythmias and Treatments
- Chemotherapy-induced cardiotoxicity and mitigation
- Heart Rate Variability and Autonomic Control
- Diamond and Carbon-based Materials Research
- Sympathectomy and Hyperhidrosis Treatments
- Electron Spin Resonance Studies
Second Xiangya Hospital of Central South University
2023-2025
Central South University
2023-2025
Abstract Objective: Head-up tilt test (HUTT) is an important tool in the diagnosis of pediatric vasovagal syncope. This research will explore relationship between syncopal symptoms and HUTT modes Methods: A retrospective analysis was performed on clinical data 2513 children aged 3–18 years, who were diagnosed with syncope, from Jan. 2001 to Dec. 2021 due unexplained syncope or pre-syncope. The average age 11.76 ± 2.83 including 1124 males 1389 females. patients divided into basic head-up...
Background. Doxorubicin-induced cardiotoxicity has been closely concerned in clinical practice. Rev-erbα is a transcriptional repressor that emerges as drug target for heart diseases recently. This study aimed at investigating the role and mechanism of doxorubicin-induced cardiotoxicity. Methods. H9c2 cells were treated with 1.5 μM doxorubicin, C57BL/6 mice 20 mg/kg cumulative dose doxorubicin to construct models vitro vivo. Agonist SR9009 was used activate Rev-erbα. PGC-1α expression level...