- Advanced biosensing and bioanalysis techniques
- Microbial Fuel Cells and Bioremediation
- Supercapacitor Materials and Fabrication
- Electrochemical sensors and biosensors
- Biosensors and Analytical Detection
- Advanced SAR Imaging Techniques
- Supramolecular Chemistry and Complexes
- Radar Systems and Signal Processing
- SARS-CoV-2 detection and testing
- Advanced Biosensing Techniques and Applications
- RNA Interference and Gene Delivery
- Hydrology and Watershed Management Studies
- Plant Virus Research Studies
- Advanced Nanomaterials in Catalysis
- Bacteriophages and microbial interactions
- Minerals Flotation and Separation Techniques
- Synthetic Aperture Radar (SAR) Applications and Techniques
- Hydrological Forecasting Using AI
- CRISPR and Genetic Engineering
- Acute Myeloid Leukemia Research
- Covalent Organic Framework Applications
- Supramolecular Self-Assembly in Materials
- Bauxite Residue and Utilization
- Electrocatalysts for Energy Conversion
- Marine and coastal ecosystems
Northwest Normal University
2024-2025
Soochow University
2022-2025
First Affiliated Hospital of Soochow University
2022-2025
Southwest Medical University
2025
Changchun Institute of Applied Chemistry
2020-2024
Chinese Academy of Sciences
2012-2024
University of Science and Technology of China
2020-2024
Qinghai University
2022-2023
Harbin Engineering University
2016-2022
Guangzhou Research Institute of Non-ferrous Metals
2020-2021
Abstract Desirable biosensing assays need to be sensitive, specific, cost‐effective, instrument‐free, and versatile. Herein we report a new strategy termed CLIPON ( C RISPR L arge DNA assembly I nduced P regnancy strips for signal‐ ON detection) that can deliver these traits. integrates commercial pregnancy test strip (PTS) with four biological elements: the human chorionic gonadotropin (hCG), CRISPR‐Cas12a, crRNA c auliflower‐like l arge‐sized D NA assemblies (CLD). uses Cas12a/crRNA...
Abstract There is a constant drive for affordable point‐of‐care testing (POCT) technologies the detection of infectious human diseases. Herein, we report simple platform DNA that takes advantage four techniques: commercially available pregnancy test strips (PTS), amplicon generation via loop‐mediated isothermal amplification (LAMP), toehold‐mediated strand displacement, and noncovalent immobilization on paper surface with nanoflowers. This simple, separation‐free highly specific, as...
Macrocyclic arenes have emerged as pivotal scaffolds in supramolecular chemistry. Despite their significant contributions to molecular recognition and diverse applications, challenges persist the development of macrocyclic arene-based crystalline materials, particularly achieving porosity addressing limitations adsorption efficiency resulting from small cavity sizes existing arenes. In this study, we present design synthesis a novel arene, clamparene (CLP), featuring rigid backbone, easy...
Coronavirus diseases such as the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome 2 (SARS-CoV-2), pose serious threats. Portable and accurate nucleic acid detection is still an urgent need to achieve on-site virus screening timely infection control. Herein, we have developed on-site, semiautomatic system, aiming at simultaneously overcoming shortcomings suffered various commercially available assays, low accuracy, poor portability, instrument...
The development of well-defined three-dimensional supramolecular polymers presents significant challenges, particularly in achieving crystalline state structures. This study addresses this challenge by presenting the construction a polymer through self-assembly clamparene (CLP) and naphthalene diimide derivative (NDIOH) solid state. hierarchical progresses from one-dimensional linear to two-dimensional ultimately polymer. Moreover, prepared demonstrates effective photothermal conversion....
Acute myeloid leukemia (AML) with retinoic acid receptor gamma (RARG) fusions, which exhibits clinical features resembling acute promyelocytic (APL), has been identified as a new subtype poor outcomes. The underlying mechanism of RARG-fusion remains poorly understood, and needs to be explored urgently instruct developing effective therapeutic strategies. Here, using the most prevalent RARG fusion, CPSF6-RARG (CR), representative, we reveal that CR enhances expansion progenitors, impairs...
Although promising in monitoring low-abundance analytes, most of the DNAzyme walker is only responsive to a specific target. Herein, universal, ready-to-use platform developed by coupling nicking-enhanced rolling circle amplification and self-powered (NERSD). It addressed issues that strands need be specifically designed for different biosensing system, allowing highly sensitive analysis various targets with same components. also owing target-dependent ligation padlock probe precise cleavage...
The present detection method for hepatitis B virus (HBV) drug-resistant mutation has a high misdiagnosis rate and usually needs to meet stringent requirements technology equipment, leading complex time-consuming manipulation drawback of costs. Herein, with the purpose developing cost-effective, highly efficient, handy diagnosis HBV mutants, we propose an electrochemical signal-on strategy through three-way junction (3WJ) transduction exonuclease III (Exo III)-assisted catalyzed hairpin...
Porous Pt nanotubes are synthesized <italic>via</italic> layer-by-layer assembly with FeOOH-nanorods as templates, exhibiting an impressive electrocatalytic performance towards methanol electrooxidation.
Wetlands play an important role in water storage and conservation, but with global climate change, the degradation of wetland ecosystems is accelerating. In this study, we conducted research on current situation future prediction quality typical wetlands source region Yangtze River to provide a scientific basis for protection restoration River. The Bayesian assessment method Yao Zhiqi evaluation were used evaluate from 2016 2021 based change scenarios three RCPs (Representative Concentration...
The impact of climate change on surface runoff and soil moisture in the source region Yellow River is analyzed, which will provide a scientific basis for rational use protection water resources area. In this paper, SWAT hydrological model was coupled with Coupled Model Intercomparison Project (CMIP) to predict future changes River. prediction Basin analyzed by linear regression model. rate had calibration period R2 0.876 validation 0.972. trend annual mean temperature from 2011 2022 showed...