A5009024120- Child Nutrition and Water Access
- Folate and B Vitamins Research
- Global Maternal and Child Health
- Food Security and Health in Diverse Populations
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Iron Metabolism and Disorders
- Obesity, Physical Activity, Diet
- Infant Nutrition and Health
- Public Health and Nutrition
- Poverty, Education, and Child Welfare
- COVID-19 Impact on Reproduction
- Advanced Proteomics Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Viral gastroenteritis research and epidemiology
- Child Nutrition and Feeding Issues
- Vaccine Coverage and Hesitancy
- Breastfeeding Practices and Influences
- Heavy Metal Exposure and Toxicity
- Arsenic contamination and mitigation
- Cancer, Lipids, and Metabolism
- Pregnancy and preeclampsia studies
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Helicobacter pylori-related gastroenterology studies
Johns Hopkins University
2022-2025
International Centre for Diarrhoeal Disease Research
2013-2024
Child Health Research Foundation
2022-2023
Begum Rokeya University
2023
Institute of Genomics and Integrative Biology
2021-2022
Food and Nutrition Service
2022
University of California, Davis
2013-2015
Agricultural Research Service
2014
Western Human Nutrition Research Center
2013
Introduction Optimising the micronutrient status of women before and during reproduction confers benefits to them their offspring. Antenatal multiple supplements (MMS), given as a daily tablet with nutrients at ~1 recommended dietary allowance (RDA) or adequate intake (AI) reduces adverse birth outcomes. However, this dosage, MMS may not fully address deficiencies in settings chronically inadequate diets infection. A bioefficacy study determine amounts required attain nutrient adequacy among...
Objective The aim of this study was to construct a predictive model in order develop an intervention reduce the prevalence stunting among children aged 12–23 months. Design followed cluster randomised pre-post design and measured impacts on various indicators livelihood, health nutrition. based large dataset collected from two cross-sectional studies (baseline endline). Setting conducted north-eastern region Bangladesh under Sylhet division, which is vulnerable both natural disasters...
There is limited research to determine whether vitamin B12 (B12) supplementation during pregnancy and lactation protective against oxidative stress pro-inflammatory cytokines this effect transferred breastfed infants via milk. In addition, associations among maternal plasma/ milk infant status immune function markers are poorly characterized.
Circulating α1-acid glycoprotein (AGP) and C-reactive protein (CRP) are commonly measured to assess inflammation, but these biomarkers fail reveal the complex molecular biology of inflammation. We mined maternal plasma proteome detect proteins that covary with AGP CRP. In 435 gravida predominantly in <12-week gestation, we correlated relative quantification assessed via a multiplexed aptamer assay (SOMAScan®) CRP, quantified by immunoassay. defined inflammasome as correlates meeting false...
Lipid compositions of cells, tissues, and bio-fluids are complex, with varying concentrations structural diversity making their identification challenging. Newer methods for comprehensive analysis lipids thus necessary. Herein, we propose a targeted-mass spectrometry based lipidomics screening method using combination variable retention time window relative dwell weightage. Using this method, identified more than 1000 lipid species within 24-min. The limit detection varied from the...
This article reviews vitamin B12 (B12) status and deficiency during pregnancy lactation, its effect on pregnancy, the health of offspring, with aim to underscore need for a sustainable strategy improve maternal infant low middle income countries.Vitamin is basic nutrient required maintenance normal erythropoiesis, cell reproduction, nucleoprotein myelin synthesis.B12 associated adverse outcomes neurodevelopmental morbidity infancy.Very few studies have indicated that may contribute altered...
Iron in groundwater provides a good source of absorbable iron for humans and can contribute to optimal haemoglobin (Hb) status among populations. We aimed examine the relationship between content anaemia 12- 23-month-old children rural area Bangladesh.A cross-sectional study was conducted 80 randomly selected unions (the lowest administrative unit) Sylhet Moulvibazar districts Bangladesh. A total 800 aged 12-23 months were via systematic random sampling method. The child's age, sex, stunting...
Abstract Malnutrition among women is a long‐standing public health concern that has significant adverse consequences on the survival and healthy development of children. Maternal mid‐upper arm circumference (MUAC) could potentially represent simpler alternative to traditional nutritional indicators. This study aimed investigate factors associated with low maternal MUAC (as an indicator being underweight) address research question whether significantly children's status poor very households...
Child wasting is defined as a weight-for-height/length z-score (WLZ/WHZ) < -2, and this indicator of nutritional status used worldwide. However, precise measurement required for the assessment child's status, which may not always be possible due to expensive instruments, especially in poor resource settings. In some instances, mid-upper arm circumference-for-age (MUACZ) also being screening purposes, simple useful indicator. The objective paper identify optimal cut-off point MUACZ wasted...
Abstract Adequate maternal healthcare practices are crucial to both and infant nutrition outcomes. The Sylhet region of Bangladesh is vulnerable performs poorly, as child health indicators falling behind compared other areas. Suchana , a large‐scale intervention programme aims improve the nutritional status mothers children in this region. objective present analysis assess changes related among beneficiaries. We obtained data from baseline endline evaluation survey. Descriptive statistics...
Despite reports of enterotoxigenic Bacteroides fragilis (ETBF) isolation from asymptomatic children, no exist regarding the possible association ETBF with long-term complications such as development environmental enteric dysfunction (EED) and subsequent linear growth faltering in childhood. We aimed to establish a potential between burden infection EED at 24 months age using data collected 1,715 children enrolled multi-country birth cohort study, known Etiology, Risk Factors, Interactions...
Abstract Exclusive breastfeeding (EBF) provides significant health benefits to children. However, mothers may find it difficult continue EBF for 6 months. The present analysis aimed examine the influence of Suchana intervention—a large‐scale programme implemented with aim improving and nutritional status children from poor households in Sylhet region Bangladesh—on stunting among under Baseline endline data were obtained evaluation. was defined as an infant (<6 months) only receiving...
Abstract Balanced energy protein (BEP) supplementation is an efficacious intervention in pregnancy for improving birthweight and recommended by World Health Organization (WHO) countries with high maternal undernutrition. Few have implemented BEP programmes due part to cost, lack of data on acceptability feasibility, complexity delivery. We sought address implementation gaps interventions through a formative study designed understand outcomes. conducted 52 in‐depth interviews 8 focus‐group...
Objectives Women’s decision-making power is a dimension of empowerment and crucial for better physical psychosocial outcomes mothers. Suchana , large-scale development programme in Bangladesh, actively provided social interventions on behaviour change communication to empower women belonging the poorest segment. This paper aims assess impact intervention various indicators related women’s power. Design, setting participants The evaluation design was cluster randomised pre-post with two...
Objective This study aimed to identify the associated factors of low and medium household (HH) dietary diversity (DD) compared with high DD among marginalised households in rural Bangladesh. Methods Through Suchana baseline survey, data on 5440 from Sylhet Moulvibazar districts Bangladesh was collected between November 2016 February 2017. Household categorised as low, or based number food groups consumed during last 24 hours. Primary outcome measure DD; multinomial logistic regression...
COVID-19 vaccines are an effective public health intervention to reduce COVID-19-related morbidity and mortality. Given that pregnant lactating women have a higher risk of severe complications, it is paramount understand the factors inform vaccine decision-making among this population. In study, we sought identify facilitators barriers acceptance promotion in Bangladesh. We conducted 40 in-depth interviews with 12 women, 16 workers from one urban four rural communities used grounded theory...
Balanced energy protein (BEP) supplementation in pregnancy is recommended the context of undernutrition for reduction small-for-gestational age neonates and stillbirths. To inform an effectiveness trial, we evaluated acceptability a packaged, ready-to-eat fortified BEP product among women reproductive their health care providers (HCPs) rural Bangladesh explored feasibility adhering to daily supplementation. We implemented formative study using focus groups discussions with (n = 29) HCPs 17)...
Despite achieving remarkable progress, food insecurity remains a major public health challenge in Bangladesh, and severe status has not been reduced susceptible areas vulnerable regions Bangladesh. Wetlands that are to flooding can be found Bangladesh's north-eastern Sylhet division. Suchana , large-scale nutrition programme, implemented nutrition-specific sensitive interventions poor very households Moulvibazar districts the region of The aim this article is assess association between...
Introduction: MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene expression. Changes in miRNA expression have been reported a number of intestinal diseases, both tissue samples and readily accessible specimens like stools. Pathogenic infections, diet, toxins, other environmental factors believed to influence However, modulation miRNAs humans is yet be thoroughly investigated. In this study, we examined the levels two human (miRNA-122 miRNA-21) stool group...