A5045447214- Child Nutrition and Water Access
- Viral gastroenteritis research and epidemiology
- Pneumonia and Respiratory Infections
- Child Nutrition and Feeding Issues
- Infant Nutrition and Health
- Vibrio bacteria research studies
- Global Maternal and Child Health
- Food Security and Health in Diverse Populations
- Clostridium difficile and Clostridium perfringens research
- Emergency and Acute Care Studies
- COVID-19 Clinical Research Studies
- Escherichia coli research studies
- Respiratory Support and Mechanisms
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 and healthcare impacts
- Vaccine Coverage and Hesitancy
- Trace Elements in Health
- Healthcare Systems and Reforms
- Global Health and Epidemiology
- Breastfeeding Practices and Influences
- Neonatal Respiratory Health Research
- Antibiotic Resistance in Bacteria
- Tuberculosis Research and Epidemiology
- Neonatal and fetal brain pathology
- Diagnosis and treatment of tuberculosis
International Centre for Diarrhoeal Disease Research
2017-2025
University of Alberta
2024
BRAC University
2024
Islamia University of Bahawalpur
2017
Disrupted development of the gut microbiota is a contributing cause childhood malnutrition.
Abstract Severe acute malnutrition (SAM) is a major global public health problem. We aimed to assess the effects of probiotic and synbiotic supplementation on rate weight gain change in length young SAM infants. This study was substudy single-blind randomized clinical trial (NCT0366657). During nutritional rehabilitation, 67 <6 months old infants were enrolled receive either ( Bifidobacterium. infantis EVC001) or B. EVC001 + Lacto-N-neotetraose [LNnT]) placebo (Lactose) for four weeks...
Background Despite oral rehydration salt (ORS) solution being a life-saving medication, mothers of affected children often lack proper knowledge and exhibit improper practice using ORS in sachets. We aimed to assess maternal knowledge, attitude towards commercially available its use treating under-5 with diarrhoea. Methods The study was conducted at the Dhaka Hospital, Bangladesh. included 350 suffering from Data were collected pretested questionnaire modified Bloom’s cut-off used determine...
Antimicrobial resistance against shigellosis is increasingly alarming. However, evidence-based knowledge gaps regarding the changing trends of in Bangladesh exist due to scarcity longitudinal data on antimicrobial resistance. Our study evaluated last 20 years patterns among under-5 children urban and rural sites Bangladesh. Data were extracted from Diarrheal Disease Surveillance System (DDSS) Dhaka Hospital (urban site) Matlab (rural International Centre for Research, (icddr,b) between...
Background: The burden of diarrhoeal diseases is considerable in South Asia, as well sub-Saharan Africa (SSA). Its economic impact more profound resource-limited settings like low- and middle- income countries (LMICs). In this study, we aimed to estimate the direct indirect cost reported by caregivers participants from seven LMICs. Methods: current study used data multicenter, Global Enteric Multicenter Study (GEMS) which enrolled under-5 children (U5C). This prospective case-control was...
Due to the scarcity of published data on growth among children with severe diarrhoea requiring readmission during post-discharge follow-up, we aimed investigate potential impact at day-90 follow-up in diarrheal aged 2-23 months. We performed a secondary analysis using Bangladesh site from Antibiotic for Children Diarrhea (ABCD) trial, multi-country, randomised, double-blind, placebo-controlled study conducted July 2017 2019. months who had defined as having acute some/severe dehydration, or...
Introduction Shigellosis is the second leading cause of diarrhoeal deaths among children worldwide. Oral azithromycin and intravenous ceftriaxone are recommended first-line second-line therapies for shigellosis in Bangladesh, respectively, but growing antibiotic resistance will require new options. Tebipenem pivoxil, an orally administered carbapenem with activity against many strains antibiotic-resistant bacteria, may be a viable option. Methods A phase IIb randomised controlled trial was...
Abstract Objective: Underweight, wasting, and stunting are crucial malnutrition indicators responsible for morbidities among children. Data regarding coexisting forms of (CFM) is scarce. We aimed to investigate the prevalence associated factors CFM across two survey years under-5 Bangladeshi Design: Cross-sectional study. Setting: were acquired from rounds Multiple Indicator Cluster Survey (MICS), Bangladesh conducted in 2012-13 2019. Subjects: The analysis included 43,946 (2012-13: 20,885;...
Data are limited on the prevalence and outcome of anemia its risk mortality among children under five years age hospitalized for pneumonia/severe pneumonia. Thus, we conducted a secondary analysis data extracted from Dhaka Hospital International Centre Diarrhoeal Disease Research, Bangladesh to address evidence gap. Among 3468 fulfilling study criteria,1712 (49.4%) had anemia. If aged ≤ 1.0, > 1.0 2.0, 2.0 < 6.0, ≥ 6.0 59 months blood hemoglobin (Hb) value 10.7 g/dL, 9.4 9.5 11 g/dl...
Abstract With more than 100,000 cases estimated each year, Bangladesh is one of the countries with highest number people at risk for cholera. Moreover, formulating a countrywide cholera-control plan to satisfy GTFCC (The Global Task Force on Cholera Control) Roadmap's goals. particular focus cholera trends, variance in baseline and clinical characteristics cases, trends antibiotic susceptibility among isolates Vibrio cholerae, we used data from facility-based surveillance systems icddr,b’s...
Worldwide, pneumonia is the leading cause of mortality in children under age five. An expanded program on immunization (EPI) one kind evidence-based tool for controlling and even eradicating infectious diseases.This study aimed to explore impact EPI vaccination, including BCG, DPT-Hib-Hep B, OPV, IPV, PCV-10, among from 4 59 months hospitalized severe pneumonia. Additionally, we evaluated role 10 valent pneumococcal conjugate vaccines alone clinical outcomes such children.In this...
To compare the health and nutrition of children younger than 5 years admitted to hospital during before coronavirus disease 2019 (COVID-19) pandemic in Bangladesh.We collected data from records 0-59 months Dhaka Hospital International Centre for Diarrhoeal Disease Research, Bangladesh March 2020-February 2021 (COVID-19 period; n = 2552) 2019-February 2020 (pre-COVID-19 6738). Data included sociodemographic, anthropometric, clinical biochemical characteristics. We compared these child...
Aims Appropriate rehydration has always been significant in treating diarrhoeal diseases children. Irrational antibiotic use among children remained a major public health concern. Information regarding young infants suffering from diarrhoea is very limited and unique aspect of research. We aimed to investigate the prevalence community 2–6 months with illnesses having different nutritional status. Methods investigated total 5279 aged at Dhaka hospital, International Centre for Diarrhoeal...
ABSTRACT. Rotavirus is the leading cause of dehydrating diarrhea among children in developing countries. The impact rotaviral on nutritional status not well understood. We aimed to determine association between rotavirus-positive moderate-to-severe and nutrition under 5 years age. analyzed data from Global Enteric Multicenter Study 0–59 months old South Asia sub-Saharan Africa. relationships explanatory variables outcome were assessed using multiple linear regression; variable was presence...
Children with both severe wasting and stunting (SWSS) represent an extreme form of malnutrition are prone to develop infection. The study aims demonstrate clinical features aetiology diarrhoea among children SWSS compared those either (SW) or (SS), which may help in early identification high-risk children.Data were extracted from the database diarrhoeal disease surveillance system (DDSS) Dhaka Hospital, icddr,b 2008 2017. Among 14 403 under-five children, 149 had concurrent (WLZ/WHZ ˂-3...
Despite reports of enterotoxigenic Bacteroides fragilis (ETBF) isolation from asymptomatic children, no exist regarding the possible association ETBF with long-term complications such as development environmental enteric dysfunction (EED) and subsequent linear growth faltering in childhood. We aimed to establish a potential between burden infection EED at 24 months age using data collected 1,715 children enrolled multi-country birth cohort study, known Etiology, Risk Factors, Interactions...
Abstract Human milk oligosaccharides (HMOs) support the development of a healthy gut microbiome and growth infants. We aimed to determine association different HMOs with severe acute malnutrition (SAM) among Bangladeshi young This study was nested within single-blind, randomized, pilot clinical trial (NCT0366657). A total 45 breastmilk samples from mothers < 6 months old infants who had SAM (n = 26) or were non-malnourished 19) analyzed for constituent HMOs. Of SAM, 14 (53.85%) secretor...
Pneumonia has been the leading infectious cause of morbidity and mortality in children under 5 years age for last several decades. Although most these deaths occur due to respiratory failure, published data are limited regarding predicting factors outcomes failure hospitalized with pneumonia or severe pneumonia.This study aimed explore prevalence, factors, under-five pneumonia.In this retrospective chart analysis, we enrolled Dhaka Hospital International Centre Diarrheal Disease Research,...
Abstract Objective The Cholera‐Hospital‐Based‐Intervention‐for‐7‐days (CHoBI7) is a water treatment and handwashing with soap intervention for diarrhoea patients their household members which initially delivered in healthcare facility setting. This study evaluated the effectiveness of CHoBI7 program delivery increasing setting among members. Methods A randomised controlled trial was conducted 404 accompanying facilities Dhaka, Bangladesh. ‘Standard Message’ Arm received standard message...
Zinc supplementation is an added intervention with oral rehydration solution (ORS) for treating childhood diarrhea as per World Health Organization recommendations. Our study aimed to determine the prevalence of zinc administration in addition ORS before hospitalization and nutritional profile those children admitted outpatient department largest diarrheal facility Bangladesh. This used a screening dataset clinical trial (www.clinicaltrials.gov; NCT04039828) on at Dhaka hospital...
Children with diarrhea often present fast breathing due to metabolic acidosis from dehydration. On the other hand, age specific is cornerstone for diagnosis of pneumonia following classification recommended by World Health Organization (WHO). Correction rehydrating diarrheal children requires time, which delays early initiation appropriate antimicrobials and thereby increases risk deaths. We need further investigate simple clinical features than might help us in earliest Thus, objective our...
Background. Breastfeeding counseling (BFC) plays a crucial role in improving infant and young child feeding practices. To evaluate the impact of activities BFC unit (BFCU) on breastfeeding practices infants who were hospitalized for diarrheal illness through their regular counseling, assistance support, motivation. Methods. In this retrospective chart analysis conducted at Dhaka Hospital icddr,b using an electronic database, data collected from mothers younger than 6 months age visited BFCU...