A5043777849- Neonatal Respiratory Health Research
- Child Nutrition and Water Access
- Respiratory Support and Mechanisms
- Viral gastroenteritis research and epidemiology
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Disaster Management and Resilience
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Clostridium difficile and Clostridium perfringens research
- Statistical Methods in Epidemiology
- Nosocomial Infections in ICU
- Flood Risk Assessment and Management
- Healthcare professionals’ stress and burnout
- Electrolyte and hormonal disorders
- Birth, Development, and Health
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Head and Neck Cancer Studies
- Bacterial biofilms and quorum sensing
- Emergency and Acute Care Studies
- Workplace Health and Well-being
- Global Maternal and Child Health
- Cardiac Health and Mental Health
- Global Health and Epidemiology
International Centre for Diarrhoeal Disease Research
2021-2025
Aga Khan University
2023
Khulna University
2021
Dhaka Medical College and Hospital
2013
Dhaka National Medical College
2013
Abstract Background Bacterial pathogens cause substantial diarrhea morbidity and mortality among children living in endemic settings, yet antimicrobial treatment is only recommended for dysentery or suspected cholera. Methods AntiBiotics Children with severe Diarrhea was a 7-country, placebo-controlled, double-blind efficacy trial of azithromycin 2–23 months age watery accompanied by dehydration malnutrition. We tested fecal samples enteric utilizing quantitative polymerase chain reaction to...
Due to the scarcity of published data on growth among children with severe diarrhoea requiring readmission during post-discharge follow-up, we aimed investigate potential impact at day-90 follow-up in diarrheal aged 2-23 months. We performed a secondary analysis using Bangladesh site from Antibiotic for Children Diarrhea (ABCD) trial, multi-country, randomised, double-blind, placebo-controlled study conducted July 2017 2019. months who had defined as having acute some/severe dehydration, or...
World Health Organization (WHO) guidelines do not recommend routine antibiotic use for children with acute watery diarrhea. However, recent studies suggest that a significant proportion of such episodes have bacterial cause and are associated mortality growth impairment, especially among at high risk diarrhea-associated mortality. Expanding dehydrated or undernourished may reduce improve growth.To determine whether the addition azithromycin to standard case management nonbloody diarrhea aged...
BackgroundThe safety and efficacy of bubble continuous positive airway pressure (bCPAP) for treatment childhood severe pneumonia outside tertiary care hospitals is uncertain. We did a cluster-randomised effectiveness trial locally made bCPAP compared with WHO-recommended low-flow oxygen therapy in children hypoxaemia general Ethiopia.MethodsThis open, was done 12 (secondary) Ethiopia. randomly assigned six to as first-line respiratory support aged 1–59 months who presented standard therapy....
Bangladesh underwent four waves of the coronavirus disease 2019 (COVID-19) pandemic. Analysing them is essential for understanding changes in viral behaviour, patterns, severity, and response to treatment. Nevertheless, data are scarce low- middle-income countries. Therefore, we aimed compare clinical manifestations; outcomes therapy with oxygen, dexamethasone, remdesivir; as well case fatality during ancestral, alpha/beta, delta, omicron-driven waves. We conducted an observational study at...
Pneumonia is a leading cause of sepsis and mortality in children under 5 years. However, our understanding the causes bacteremia with pneumonia limited. We characterized risk factors for death cohort admitted to Dhaka Hospital International Centre Diarrhoeal Disease Research, Bangladesh (icddr,b) between 2014 2017 radiographically confirmed pneumonia. A total 4007 young were hospitalized over study period. 1814 (45%) had blood cultures obtained. Of those, 108 (6%) positive. Gram-negative...
Malnutrition in women has been a long-standing public health concern, with serious effects on child survival and development. Maternal body mass index (BMI) is an important maternal nutritional indicator. There are few published studies although anthropometric failures do not occur isolation identifying children single versus several co-occurring can better capture cases of growth failure combination: stunting, wasting, underweight. In the context multiple failures, traditional markers used...
Despite the beneficial effect of bubble continuous positive airway pressure (BCPAP) oxygen therapy for children with severe pneumonia under supervision physicians that has been shown in different studies, effectiveness trials developing country settings where low-flow is standard care are still needed. Thus, aim this study to assess CPAP compared WHO among hospitalized and hypoxemia Ethiopia. This a cluster randomized controlled trial six district hospitals BCPAP therapy. The total sample...
Background In low and middle-income countries (LMICs), severe pneumonia with hypoxemia is the leading cause of child deaths, even provision WHO-recommended antibiotic therapy, oxygen therapy other supportive care. Previous studies found positive outcomes from use bubble continuous airway pressure (bCPAP) for treating these children compared to standard therapy. Due lack data on perceptions experiences hospital health care workers caregivers feasibility acceptability bCPAP in real-life...
Abstract Background After the completion of a randomized trial at Dhaka Hospital in 2013, bubble continuous positive airway pressure (BCPAP) oxygen therapy was incorporated as part standard treatment for children with severe pneumonia hypoxemia an intensive care unit August 2013 instead World Health Organization (WHO) low flow therapy. Objective To understand long‐term effectiveness introduction bCPAP by comparing mortality post‐trial period (August to December 2017) pre‐trial (February 2009...
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Approximately 12% of all diarrhoeal episodes last for 7-13 days. As such, they are termed prolonged diarrhoea, and associated with over two-thirds deaths. Due to a lack robust data, we aimed evaluate comparative background characteristics young children acute their outcomes at day 90 follow-up.
Effective management of hypoxaemia is key to reducing pneumonia deaths in children. In an intensive care setting within a tertiary hospital Bangladesh, bubble continuous positive airway pressure (bCPAP) oxygen therapy was beneficial this population. To inform future trial, we investigated the feasibility introducing bCPAP population non-tertiary/district hospitals Bangladesh.We conducted qualitative assessment using descriptive phenomenological approach understand structural and functional...
Background: Pneumonia is the leading infectious cause of deaths in children under 5 for last few decades. Development seizure those common and associated with increased risk deaths. We therefore investigated prevalence, factors outcome hospitalized pneumonia. Methods: conducted a retrospective chart analysis intensive care unit Dhaka Hospital icddr,b. Children World Health Organization (WHO) classified clinical (excluding as 1 diagnostics) radiologic pneumonia, admitted to at icddr,b between...
Abstract Due to the significant number and its effects on quality of life, depression is becoming a major concern worldwide. Though prevalence among junior healthcare professionals also increasing day by day, still very few data are available regarding this. So, we’ve conducted study find out associated factors this vulnerable population. A total 218 participants were enrolled from two public teaching tertiary-level hospitals in Dhaka, Bangladesh October 2018 April 2019. Data collected using...
Introduction: Presently, there has been an emergent concern that rising numbers of the world’s population are deserted due to undesirable impacts natural hazards, especially floods. Geographically, Bangladesh is a low-lying flood plain country with only few hills in south-east and north-east part. Undoubtedly, education principal factor socio-economic development, but regrettably, suffering from uncontainable effects After considering such issues, foremost focus this study was recognize both...
Antibiotic exposure in the pediatric intensive care unit (PICU) is very high, although 50% of all antibiotics may be unnecessary. We aimed to determine utility simple bedside screening tools and predicting factors avoid antibiotic overuse ICU among children with diarrhea critical illness.We conducted a retrospective, single-center, case-control study that included aged 2-59 months who were admitted PICU illness between 2017 2020.We compared young did not receive (cases, n = 164) during stay...
Background: The safety and efficacy of bubble continuous positive airway pressure (bCPAP) in treating childhood severe pneumonia outside tertiary care hospitals is uncertain. We conducted a cluster randomized effectiveness trial bCPAP compared to World Health Organization (WHO) recommended low flow (LF) oxygen therapy general Ethiopia.Methods: A was done 12 (clusters) Ethiopia. In 6 intervention hospitals, introduced as first-line respiratory support for children 1-59 months who presented...
ABSTRACT. Children with malnutrition present aberrant laboratory parameters. This study aimed to identify high-risk diarrheal children varied nutritional status. The data were obtained from the electronic database of Dhaka Hospital, International Centre for Diarrhoeal Disease Research, Bangladesh 2019 2021. Among 1,068 under 5 years age diarrhea, 177 (14%) had severe acute (SAM; weight-for-length/height Z score < −3), 239 (17%) stunting (SS; length/height-for-age and 652 did not have...
A prospective randomized trial was performed to evaluate the combination of neoadjuvant chemotherapy in patient with oral squamous cell carcinoma. Prognosis carcinoma cavity is worth improving. Chemotherapy has been reported specially active tumour. It enrolling patients stage T2, T3, T4 NO NI N2 MO untreated cavity. Number this study 25, suffering from This a Prospective conducted among randomly selected 25 cases histopathologically diagnosed Squamous Department Oral and Maxillofacial...
Abstract Antibiotic exposure in the intensive care unit (ICU) is very high, although 50% of all antibiotics may be unnecessary. We aimed to determine predicting factors, outcomes, and utility simple screening tools avoid antibiotic overuse ICU. analyzed 510 young children who did not receive during ICU stay those treated with antibiotics. The logistic regression analysis revealed that cases were more often older independently associated hypernatremia. Cases less had severe underweight,...
Introduction: Presently, there has been an emergent concern that rising numbers of the world’s population are deserted due to undesirable impacts natural hazards, especially floods. Geographically, Bangladesh is a low-lying flood plain country with only few hills in south-east and north-east part. Undoubtedly, education principal factor socio-economic development, but regrettably, suffering from uncontainable effects After considering such issues, foremost focus this study was recognize both...