A5034395294- SARS-CoV-2 and COVID-19 Research
- Obesity and Health Practices
- COVID-19 and healthcare impacts
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Biosensors and Analytical Detection
- Liver Diseases and Immunity
- Hepatitis Viruses Studies and Epidemiology
- Liver Disease and Transplantation
University of Hong Kong
2020-2023
Chinese University of Hong Kong
2023
Queen Mary Hospital
2022
Early antiviral therapy was effective in the treatment of coronavirus disease 2019 (COVID-19). We assessed efficacy and safety combined interferon beta-1b remdesivir hospitalized COVID-19 patients.We conducted a multicentre, prospective open-label, randomized-controlled trial involving high-risk adults for COVID-19. Patients were randomly assigned to 5-day 16 million units daily 200 mg loading on day 1 followed by 100 2 5 (combination group), or only similar regimen (control group) (1:1)....
Abstract Aim To evaluate the long‐term associations between coronavirus disease 2019 (COVID‐19) and diabetes complications mortality, in patients with diabetes. Materials Methods People diagnosed COVID‐19 infection (exposed group), from 16 March 2020 to 31 May 2021 UK Biobank (UKB cohort; n = 2456), 1 April 2022 electronic health records Hong Kong (HK 80 546), were recruited. Each patient was randomly matched participants but without (unexposed based on age sex (UKB, 41 801; HK, 391 849)....
Hepatitis E virus (HEV) is an important cause of hepatitis, which can be transmitted via the bloodborne route. However, risk hepatitis among persons who inject drugs (PWIDs) poorly understood. This study aimed to elucidate whether PWIDs are at for E. We performed HEV IgM, IgG and nucleic acid detection on a cohort 91 age- sex-matched organ donors. Blood was measured using WHO antibody standard. The effects age, gender addictive injection use serostatus concentration were assessed....
Immunofluorescence is a traditional diagnostic method for respiratory viruses, allowing rapid, simple and accurate diagnosis, with specific benefits of direct visualization antigens-of-interest quality assessment. This study aims to evaluate the potential indirect immunofluorescence as an in-house SARS-CoV-2 antigens from nasopharyngeal swabs (NPS). Three primary antibodies raised mice were used staining, including monoclonal antibody against SARS-CoV nucleocapsid protein, polyclonal protein...
Antigen detection rapid diagnostic tests have been developed for first-line large-scale screening given their rapidity, simplicity, and accuracy. This study evaluates the performance of an antigen test (BLOK BioScience, London, UK) detecting SARS-CoV-2 nucleocapsid protein. Serially diluted isolate 110 NPS from COVID-19 patients were tested to determine test’s sensitivity, other viral isolates 20 non-infected individuals were, specificity, also tested. Ten clinical samples with variants,...