- earthquake and tectonic studies
- High-pressure geophysics and materials
- Geological and Geochemical Analysis
- Seismology and Earthquake Studies
- Seismic Waves and Analysis
- Seismic Imaging and Inversion Techniques
- Geomechanics and Mining Engineering
- Rock Mechanics and Modeling
- Virus-based gene therapy research
- Soil, Finite Element Methods
- RNA modifications and cancer
- Earthquake Detection and Analysis
- Cancer-related molecular mechanisms research
- Sports Dynamics and Biomechanics
- Metal-Catalyzed Oxygenation Mechanisms
- RNA Interference and Gene Delivery
- Cancer-related gene regulation
- Geophysics and Gravity Measurements
- Landslides and related hazards
- Flow Measurement and Analysis
- Geological and Geophysical Studies
- RNA Research and Splicing
- Glutathione Transferases and Polymorphisms
- Experimental and Theoretical Physics Studies
- Environmental and Sediment Control
China Earthquake Administration
2012-2025
Guangzhou Institutes of Biomedicine and Health
2009-2023
Chinese Academy of Sciences
2007-2023
University of Chinese Academy of Sciences
2015-2021
Guangzhou Regenerative Medicine and Health Guangdong Laboratory
2021
Guangzhou Medical University
2021
Jinan University
2006-2020
National Institute of Hospital Administration
2020
Chinese Academy of Geological Sciences
2020
On May 21, 2021, the M7.3 Maduo earthquake occurred within Bayan Har Block, one of most seismically active regions in Tibetan Plateau. This aroused attention to seismic hazards this block. Understanding stress transfer adjacent faults is important for assessing hazards. In study, based on elastic dislocation theory and a multi-layered lithospheric model, we calculate Coulomb failure changes caused by event major identify segments that experienced significant increases stress. Our preliminary...
The Axl gene is known to encode for a receptor tyrosine kinase involved in the metastasis process of cancer.In this study, we investigated underlying molecular mechanism alternative splicing.Methods: expression levels PTBP1 hepatocellular carcinoma (HCC) tissues were obtained from TCGA samples and cell lines.The effect Axl-L, Axl-S, on growth, migration, invasion tumor formation, liver cancer cells measured by proliferation, wound-healing, invasion, xenograft metastasis.Interaction between...
ABSTRACT Investigating how locked patches hinder sliding in adjacent regions along strike‐slip faults is crucial for understanding fault coupling distribution. We develop a 3‐D viscoelastic finite element model integrating vertical with to investigate spatiotemporal interseismic (ISC). The ISC ≥ 0.8 enclosed zone remains nearly constant, while other partial zones expand due effects. = zone, typically indicative of strong zones, tends overestimate the patch by up 1.8 times. Significant...
Steroid receptor RNA activator 1 (SRA1) has been described as a novel transcriptional co-activator that affects the migration of cancer cells. Through RT-PCR, we identified skipping exon 3 SRA1 produces two isoforms, including truncated short isoform, SRA1-S, and long SRA1-L. However, effect these isomers on HCC cells, well specific mechanism remain unclear. In this study, found up regulated expression SRSF1 SRA1-L in highly metastatic HCCLM3, HCCs with demonstrating strongest correlation...
Abstract Lung cancer is a serious threat to human health. Studies have revealed that manganese superoxide dismutase ( hSOD2 ) and miRNAs play an essential role in the metastasis process of lung cancer. However, associated with involved metastasis, remain elusive. After databases analysis dual luciferase reporter validation, we demonstrated miR‐330‐3p expression inversely correlated hSOD2b level, directly targeted 3′untranslated region (3′UTR) . Furthermore, overexpression promoted whereas...
Abstract The present tectonic regime of the Qilian Shan is dominated by large northeast and northwest striking strike‐slip faults thrust faults. Deformation distribution between subparallel Haiyuan Strike‐slip Fault Minle‐Damaying Thrust (MDF) crucial for understanding orogenic mechanism northeastern Tibetan Plateau. However, uncertain kinematics MDF stress variation along strike‐varying inhibit further discussion their relationship. Five key sites were selected analysis terrace abandonment...
Coseismic deformation and stress change are important for geodetic interpretation seismic hazard assessment. Most existing coseismic models based on the simplified geometry, such as homogeneous half-space model or symmetric spherical earth model. In this work, taking advantage of high-resolution parallel finite element methods, we construct a realistic full 3-D ellipsoidal to properly account effects topography, lateral heterogeneity, curvature Earth geometry variations at discontinuities...
Abstract The latest hydraulic fracturing and stress relief measurement data of Chinese mainland were collected supplemented to “Database Crustal Stress in China Adjacent Areas” which was established 2003. They include 3586 situ at 1474 points. are distributed a space longitudes 75°E–130°E, latitudes 18°N–47°N, depths 0~4000 meters covering all active blocks north‐south seismic belt great importance tectonic research. Depth‐grouping analysis made this paper solve the problem caused by uneven...
Abstract The 2021 Mw 7.4 Maduo earthquake in Qinghai, China, filled the seismic gap eastern segment of northern boundary Bayan Har Block, and four other M > 7 historical strong earthquakes occurred at northeastern end Block within a period 80 years before earthquake. This series large events provides an excellent example for investigating stress transfer fault interactions on continent. In this study, we established viscoelastic numerical model to calculate after produced by Block. We...
Understanding earthquake rupture propagation across fault stepovers is pivotal for assessing the seismic hazard, offering vital insights into dynamic processes within intricate geometries. However, role of poroelastic effects strike-slip systems featuring remains unexplored in models simulating Sequences Earthquakes and Aseismic Slip (SEAS). Many existing neglect effects, among those that consider them, a typical standard value 0.8 adopted Skempton's coefficient B. Furthermore, single...