A5100523713- Fibroblast Growth Factor Research
- RNA modifications and cancer
- Advanced oxidation water treatment
- Cancer, Hypoxia, and Metabolism
- Alzheimer's disease research and treatments
- Cancer-related molecular mechanisms research
- Advanced Glycation End Products research
- Influenza Virus Research Studies
- Environmental remediation with nanomaterials
- interferon and immune responses
- Respiratory viral infections research
- Cancer-related gene regulation
- Neurological Disease Mechanisms and Treatments
- RNA Research and Splicing
- Natural Antidiabetic Agents Studies
- Advanced Photocatalysis Techniques
- Bioactive Compounds and Antitumor Agents
- Peptidase Inhibition and Analysis
- MicroRNA in disease regulation
- Liver physiology and pathology
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- Biochemical and Molecular Research
- Glycosylation and Glycoproteins Research
- Proteoglycans and glycosaminoglycans research
Yancheng Institute of Technology
2001-2024
Hunan Normal University
2024
Hunan Provincial People's Hospital
2024
Jinan University
2014-2024
Shantou University
2024
First Affiliated Hospital of Shantou University Medical College
2024
Shantou University Medical College
2024
State Key Laboratory of Pollution Control and Resource Reuse
2024
Nanjing University
2024
Renji Hospital
2021-2023
The PC12 cell line is a classical neuronal model due to its ability acquire the sympathetic neurons features when deal with nerve growth factor (NGF). In present study, authors used variety of different methods induce cells, such as Opti-MEM medium containing concentrations fetal bovine serum (FBS) and horse compared RPMI-1640 medium, then observed neurite length, differentiation, adhesion, proliferation action potential, well protein levels axonal growth-associated 43 (GAP-43) synaptic...
The Axl gene is known to encode for a receptor tyrosine kinase involved in the metastasis process of cancer.In this study, we investigated underlying molecular mechanism alternative splicing.Methods: expression levels PTBP1 hepatocellular carcinoma (HCC) tissues were obtained from TCGA samples and cell lines.The effect Axl-L, Axl-S, on growth, migration, invasion tumor formation, liver cancer cells measured by proliferation, wound-healing, invasion, xenograft metastasis.Interaction between...
In this study, ozonation treatment of C.I. Reactive Black 5 (RB5) was investigated at various operating parameters. The results showed that the aqueous solution initially containing 200 mg/L RB5 quickly decolorized pH 8.0 with an ozone dose 3.2 g/h. Reaction intermediates m/z 281, 546, 201, 350, 286 and 222 were elucidated using liquid chromatography-mass spectrometry, while sulfate ion, nitrate ion three carboxylic acids (i.e., oxalic acid, formic acetic acid) identified by exchange...
Steroid receptor RNA activator 1 (SRA1) has been described as a novel transcriptional co-activator that affects the migration of cancer cells. Through RT-PCR, we identified skipping exon 3 SRA1 produces two isoforms, including truncated short isoform, SRA1-S, and long SRA1-L. However, effect these isomers on HCC cells, well specific mechanism remain unclear. In this study, found up regulated expression SRSF1 SRA1-L in highly metastatic HCCLM3, HCCs with demonstrating strongest correlation...
OPINION article Front. Cell. Neurosci., 23 November 2016Sec. Non-Neuronal Cells Volume 10 - 2016 | https://doi.org/10.3389/fncel.2016.00269
Glucagon-like peptide (GLP)-1 is an incretin hormone that acts after food intake to stimulate insulin production, enhance satiety, and promote weight loss. Here we describe the discovery characterization of ecnoglutide (XW003), a novel GLP-1 analog.We engineered series analogs with alanine valine substitution (Ala8Val) γGlu-2xAEEA linked C18 diacid fatty acid at various positions. Ecnoglutide was selected characterized in receptor signaling assays vitro, as well db/db mice diet induced obese...
Abstract Lung cancer is a serious threat to human health. Studies have revealed that manganese superoxide dismutase ( hSOD2 ) and miRNAs play an essential role in the metastasis process of lung cancer. However, associated with involved metastasis, remain elusive. After databases analysis dual luciferase reporter validation, we demonstrated miR‐330‐3p expression inversely correlated hSOD2b level, directly targeted 3′untranslated region (3′UTR) . Furthermore, overexpression promoted whereas...
Background: Recently, various evidence has confirmed that Tyrosine Kinase with Immunoglobulin-like and EGF-like domains 1 (TIE1) promotes tumor growth in many cancers.However, the precise mechanism underlying TIE1's involvement Gastric Cancer (GC) remains elusive.This research aimed to investigate biological function of TIE1 regulating GC progression.Methods: The Genome Atlas (TCGA), Gene Expression Omnibus (GEO), GEPIA2.0,Sangerbox3.0 TIMER databases were used analyze...
The generation of β‑amyloid protein (Aβ) is considered a key step in the pathogenesis Alzheimer's disease (AD) and regulation its production an important therapeutic strategy. It was hypothesized present study that Nogo‑A may be involved AD regulate Aβ. known to act as major inhibitor neuron regeneration adult central nervous system. A recent indicated associated with AD; however, underlying effect molecular mechanisms remain largely elusive. In study, potential effects on were investigated....