A5073337272- Spectroscopy Techniques in Biomedical and Chemical Research
- Forest ecology and management
- Spectroscopy and Chemometric Analyses
- Remote Sensing and LiDAR Applications
- Forensic Fingerprint Detection Methods
- Ethics in Clinical Research
- Genetic diversity and population structure
- Gold and Silver Nanoparticles Synthesis and Applications
- Genetic Mapping and Diversity in Plants and Animals
- Photonic and Optical Devices
- Molecular Biology Techniques and Applications
- Genetic and phenotypic traits in livestock
- Genetic Associations and Epidemiology
- Adipose Tissue and Metabolism
- Race, Genetics, and Society
- Animal testing and alternatives
- CRISPR and Genetic Engineering
- Peroxisome Proliferator-Activated Receptors
- Genomics and Phylogenetic Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Forensic and Genetic Research
- Carcinogens and Genotoxicity Assessment
- Pesticide Exposure and Toxicity
- Laser-induced spectroscopy and plasma
- Identification and Quantification in Food
University of Otago
2014-2024
United States Department of the Army
2010-2024
U.S. Army Combat Capabilities Development Command Chemical Biological Center
2010-2024
United States Army Combat Capabilities Development Command
2022-2024
United States Army
2010-2023
Maurice Wilkins Centre
2023
DEVCOM Army Research Laboratory
2011-2017
Future Forests Research
2014
Johns Hopkins University
2014
CECOM Software Engineering Center
2010-2013
He Tangata Kei Tua, a relationship model for biobanks, was developed to facilitate best practice in addressing Māori ethical concerns by guiding culturally informed policy and biobanks relation governance, operational, community engagement activities.The is based on key issues of relevance that were identified as part the Health Research Council New Zealand-funded research project, Te Mata Ira (2012-2015).This project perspectives biobanking genetic research, along with tikanga it cultural...
The detection of "signatures selection" is now possible on a genome-wide scale in many plant and animal species, can be performed population-specific manner due to the wealth per-population genotype data that available. With genomic regions exhibit evidence having been under selection shown also enriched for genes associated with biologically important traits, selective pressure emerging as an additional approach identifying novel gene-trait associations. While high-density relatively easy...
PERSPECTIVE article Front. Public Health, 24 April 2020Sec. Health Policy Volume 8 - 2020 | https://doi.org/10.3389/fpubh.2020.00111
We have previously demonstrated the use of wide-field Raman chemical imaging (RCI) to detect and identify presence trace explosives in contaminated fingerprints. In this current work we demonstrate detection fingerprints on strongly scattering surfaces such as plastics painted metals using an automated background subtraction routine. partial least squares minimize interfering surface spectral signatures, allowing identification explosive materials corrected images. The resulting analyses are...
Several reviews in the past decade have heralded benefits of embracing high‐throughput sequencing technologies to inform conservation policy and management threatened species, but few offered practical advice on how expedite transition from genetics genomics. Here, we argue that an effective efficient way navigate this is capitalize emerging synergies between primary industry (e.g., agriculture, fisheries, forestry horticulture). demonstrate building strong relationships geneticists...
Waveguide-enhanced Raman spectroscopy (WERS) is an analytical technique frequently employed for chemical and biological sensing. Operation at visible wavelengths to harness the inverse fourth power with excitation wavelength signal scaling of scattering intensity desirable, combat inherent inefficiency spectroscopy. Until now, WERS demonstrations in have required custom materials fabrication, resulting high losses low yields. In this work, we demonstrate a silicon nitride (SIN) platform...
Non-key traits (NKTs) in radiata pine (Pinus D. Don) refer to other than growth, wood density and stiffness, but still of interest breeders. Branch-cluster frequency, stem straightness, external resin bleeding internal checking are examples such targeted for improvement research programmes. Genomic selection can be conducted before the performance candidates is available so that generation intervals reduced. Radiata a species with long interval, which if reduced could significantly increase...
Development of genome-wide resources for application in genomic selection or association studies, the absence full reference genomes, present a challenge to forestry industry, where longer breeding cycles could benefit from accelerated possible through marker-based value predictions. In particular, large conifer megagenomes require strategy reduce complexity, whilst ensuring coverage is achieved. Using transcriptome-based template, we have successfully developed high density exome capture...
Concentrated drinking water extracts prepared by adsorption onto XAD-2 resin have been tested for their ability to induce chromosome damage in mammalian cells. Extracts from waters derived upland and lowland sources found aberrations Chinese hamster ovary (CHO) cells human lymphocytes vitro. Although the identity of compounds responsible this activity is unknown, they are generated when chlorinated appear bind readily exogenous protein. When groups mice were dosed orally with a concentrated...
Te Mata Ira was a three-year research project (2012–2015) that explored Māori views on genomic and biobanking for the development of culturally appropriate guidelines. A key component this process has been to identify concepts provide cultural reference points engaging with research. These cues basis describing logic underpins engagement in context acceptable manner. This paper outlines role two wānanga (workshops) conducted as part larger were used make sense emerged from other...
Standard protocols for extracting genomic DNA from Pinus radiata D. Don needles, such as CTAB-based methods, can yield large quantities of DNA. However, final purity be an issue due to carry over contaminants that impede accurate high throughput genotyping. This study evaluated eight extraction and purification determine which method provided the greatest improvement in call rates accuracy when using Sequenom iPLEX® Gold MassARRAY® genotyping technology. Of methods tested, extracted...
There is considerable concern regarding the biological plausibility of response certain chemicals in vitro photoclastogenicity assay, suggesting that this assay oversensitive and lacks specificity. To explore further, four coded compounds (aminotriazole, propantheline bromide, cycloheximide disulfoton) were evaluated for their potential a cultured Chinese hamster ovary (CHO) cells. None shown to absorb ultraviolet radiation (UVR) or visible light 290- 700-nm region electromagnetic spectrum....
We present the results of a three-year collaboration between U.S. Army Edgewood Chemical Biological Center and Research Laboratory-Aldelphi Laboratory on evaluation selected nanometallic surfaces developed for Defense Advanced Projects Agency Surface-Enhanced Raman Scattering (SERS) Science Technology Fundamentals program. The primary role two labs was to develop analytical spectroscopic figures merit unambiguously compare sensitivity reproducibility various SERS substrates submitted by...
Raman cross sections and spectra were measured for five synthetic opioid fentanyl analogs: citrate, sufentanil alfentanil HCl, carfentanil oxalate, remifentanil HCl. The measurements performed with excitation wavelengths in the visible (532 nm) near infrared (785 nm). In addition, density functional theory (DFT) calculations employed to generate simulated of compounds aid identification observed spectral modes. These cross-section also used assess results from a series fentanyls cut other...
There is a wide diversity of bioinformatic tools available for the assembly next generation sequence and subsequence variant calling to identify genetic markers at scale. Integration genomics such as genomic selection, association studies, pedigree analysis diversity, into operational breeding goal New Zealand's most widely planted exotic tree species, Pinus radiata. In absence full reference genomes large megagenomes in conifers, RNA sequencing range genotypes tissue types, offers rich...
Surface-enhanced Raman spectroscopy (SERS) has been shown to be an effective technique for increasing the detection sensitivity in chemical and biological applications. SERS a distinct advantage over normal spectroscopy, with enhancements typically greater than 10 4 signal; however, this comes caveat: controlling spectroscopic reproducibility enhancement activity of metal nanostructured substrates can difficult. We present survey subsequent data analysis performed on several designed SERS,...
Associations of single nucleotide polymorphisms (SNP) with the form traits, branch cluster frequency and stem straightness, were studied in three radiata pine (Pinus D. Don) breeding populations. For frequency, high genotype by environment (G×E) interactions found between two sites POP1 trial series (Tarawera Glenledi) POP2 Woodhill). G×E Woodhill) both POP3 series. Thirty-two 26 SNPs associated straightness respectively, across a number genetic model assuming heterogeneous additive...