A5018187953- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Nosocomial Infections in ICU
- Migration, Health and Trauma
- Grief, Bereavement, and Mental Health
- Global Maternal and Child Health
- Pneumocystis jirovecii pneumonia detection and treatment
National Institute of Public Health
2023
Angkor Hospital for Children
2020-2023
Cambodia-Oxford Medical Research Unit
2020-2023
Tufts University
2020
<ns4:p><ns4:bold>Background</ns4:bold>: Antimicrobial resistance (AMR) / drug resistant infections (DRIs) are a major global health priority. Surveillance data is critical to inform infection treatment guidelines, monitor trends, and assess interventions. However, most existing AMR DRI surveillance systems passive pathogen-based with many potential biases. Addition of clinical patient outcome would provide considerable added value surveillance.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>:...
<ns4:p><ns4:bold>Background</ns4:bold>: Antimicrobial resistance (AMR) / drug resistant infections (DRIs) are a major global health priority. Surveillance data is critical to inform infection treatment guidelines, monitor trends, and assess interventions. However, most existing AMR DRI surveillance systems passive pathogen-based with many potential biases. Addition of clinical patient outcome would provide considerable added value surveillance.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>:...
This study sought to characterize pneumococcal colonization and clinical/radiological features in Cambodian children admitted hospital with an illness compatible pneumonia following national introduction of the 13-valent conjugate vaccine (PCV13).Children aged 0-59 months Angkor Hospital for Children who met World Health Organization (WHO) case definition clinical were enrolled over a 3-year period. Clinical, radiological vaccination data collected at enrolment. A nasopharyngeal swab was...
(the pneumococcus) is a leading cause of childhood mortality globally and in Cambodia. It commensal the human nasopharynx, occasionally resulting invasive disease. Monitoring population genetic shifts, characterized by lineage serotype expansions, as well antimicrobial-resistance (AMR) patterns crucial for assessing predicting impact vaccination campaigns. We sought to elucidate background (global pneumococcal sequence clusters; GPSCs) pneumococci carried Cambodian children following...
Background Collecting data on antimicrobial resistance (AMR) is an essential approach for defining the scope of AMR problem, developing evidence-based interventions and detecting new emerging resistances. Our study aimed to identify key factors influencing implementation a laboratory-based surveillance system in Cambodia. This will add additional insights development sustainable effective national Cambodia other low- middle-income countries. Methods Key informants with role governing or...
<ns4:p><ns4:bold>Background: </ns4:bold>Case-based surveillance of antimicrobial resistance (AMR) provides more actionable data than isolate- or sample-based surveillance. We developed A Clinically Oriented Resistance Network (ACORN) as a lightweight but comprehensive platform, in which we combine clinical collection with diagnostic stewardship, microbiological and visualisation the linked clinical-microbiology dataset. Data are compatible WHO GLASS can be stratified by syndrome other...