A5088773512- Tuberculosis Research and Epidemiology
- Aquatic Ecosystems and Phytoplankton Dynamics
- Parasitic Infections and Diagnostics
- Algal biology and biofuel production
- Mycobacterium research and diagnosis
- Thermography and Photoacoustic Techniques
- Helicobacter pylori-related gastroenterology studies
- Tryptophan and brain disorders
- Infectious Diseases and Tuberculosis
- Stress Responses and Cortisol
- Marine and coastal ecosystems
- Respiratory viral infections research
- RNA and protein synthesis mechanisms
- Inflammatory Biomarkers in Disease Prognosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Advanced Measurement and Detection Methods
- Pharmaceutical and Antibiotic Environmental Impacts
- Biocrusts and Microbial Ecology
- Gastric Cancer Management and Outcomes
- Hepatitis B Virus Studies
- RNA Interference and Gene Delivery
- Protist diversity and phylogeny
- Hepatitis C virus research
- Ultrasonics and Acoustic Wave Propagation
- Diagnosis and treatment of tuberculosis
Gansu Provincial Hospital
2014-2025
Guangxi Communication Design Group Co., LTD (China)
2024-2025
China Design Group (China)
2024-2025
Gansu University of Traditional Chinese Medicine
2025
Institute of Hydrobiology
2015-2023
Chinese Academy of Sciences
2015-2023
Beijing University of Agriculture
2016-2023
Ministry of Agriculture and Rural Affairs
2023
Qingdao National Laboratory for Marine Science and Technology
2019
Jiangxi Science and Technology Normal University
2018
Metabolic reprogramming is characterized by dysregulated levels of metabolites and metabolic enzymes. Integrated metabolomic transcriptomic data analysis can help to elucidate changes in the enzymes, screen core pathways, develop novel therapeutic strategies for cancer.Here, metabolome gastric cancer tissues was determined using liquid chromatography-mass spectrometry. The transcriptome from Cancer Genome Atlas dataset were integrated with spectrometry identify common cancer-specific...
Background Previous studies indicated that some routine hematological parameters are associated with the prognosis of ischemic stroke ( IS ), but none study has evaluated them simultaneously. The aim this was to investigate prognostic value in patients. Methods Using medical record database, we retrospectively reviewed patients admitted Gansu Province Hospital between June 2014 and July 2015. on admission analyzed using logistic regression model, receiver operating characteristic ROC ) curve...
This paper addresses the challenges in assessing health status of reinforced concrete (RC) components large civil structures by proposing a novel method for identifying damage stages. The proposed approach leverages cumulative energy slope acoustic emission (AE) signals and hidden Markov model (HMM) to predict Three main innovations are highlighted: firstly, improve accuracy stage prediction, integration 'cumulative energy-time' data from AE into HMM is introduced. Secondly, overcome...
<title>Abstract</title> <bold>Background: </bold>The relationship between dietary oxidative balance and mortality among cancer patients remains unclear, particularly concerning the moderating effects of depression cancer-specific mortality. This study aimed to evaluate associations Dietary Oxidative Balance Score (DOBS) Circulating Antioxidants Index (CAI) with risk in patients, emphasizing influence status. <bold>Methods: </bold>Data were derived from two National Health Nutrition...
Although the Ficoll-Paque method is classically used to isolate peripheral blood mononuclear cells (PBMCs), modifications in this are required for a more rapid and economic output biobanks clinical laboratories, particularly developing countries. In study, we addressed issue by modifying isolation of PBMCs or from umbilical cord healthy diseased (infected, anemic, chronic obstructive pulmonary disease) adult individuals. modified method, initiated cell process buffy coat layer, which appears...
Hypothalamic dysfunction is a key pathological factor in inflammation-associated depression. In the present study, isobaric tags for relative-absolute quantitation (iTRAQ) combined with mass spectrometry and gas chromatography-mass (GC-MS) were employed to detect proteomes metabolomes hypothalamus of lipopolysaccharide (LPS)-induced depression mouse, respectively. A total 187 proteins 27 metabolites differentially expressed compared control group. Following integration bi-omics data,...
Improper management of aquatic environments substantially restricts the development aquaculture industry. The industrialisation crayfish Procambarus clarkii, for example, is currently being limited by poor water quality. Research suggests that microalgal biotechnology has a great potential quality regulation. However, ecological effects applications on communities in systems remain largely unknown. In present study, 5 L Scenedesmus acuminatus GT-2 culture (biomass 120 g L-1) was added to an...
Abstract Background Depression is two-to-three times more frequent among women. The hypothalamus, a sexually dimorphic area, has been implicated in the pathophysiology of depression. Neuroinflammation-induced hypothalamic dysfunction underlies behaviors associated with lipopolysaccharide (LPS)-induced mouse model depression well-validated numerous laboratories, including our own, and widely used to investigate relationship between neuroinflammation However, sex-specific differences metabolic...
Imbalances of amino acids and the purinergic system show significant hypothalamic metabolic perturbations, which are closely associated with mechanisms depression.
BCG, the only registered vaccine against Mycobacterial Tuberculosis (TB) infection, has been questioned for its protective efficacy decades. Although lots of efforts were made to improve BCG antigenicity, few studies devoted understand role host factors in variability protection. Using IL-10KO mice and pulmonary tuberculosis infection model, we have addressed IL-10 vaccination efficacy. The data showed that IL-10-deficient dendritic cells (DCs) could promote immune responses through...
Splicing dysregulation, which leads to apoptosis resistance, has been recognized as a major hallmark for tumorigenesis and cancer progression. Targeting alternative splicing by either increasing pro-apoptotic proteins or inhibiting anti-apoptotic in tumor cells may be an effective approach gastric (GC) therapy. However, the role of modulation GC remains poorly understood. In this study, best our knowledge, unbalanced expression myeloid cell leukemia-1 (Mcl-1) variants, Mcl-1L Mcl-1S, was...
Mixotrophic flagellates play an important role in connecting the classical food chain and microbial loop. The feeding characteristics of mixotrophic flagellate Poterioochromonasmalhamensis have been well studied, but its as a source for other large zooplankton is less studied. This study focuses on physiological biochemical changes P. malhamensis when using autotrophy, chemoheterotrophy, phagotrophy, effect these ability one predators, ciliate Paramecium caudatum. results showed that...