- Advanced Neuroimaging Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Dementia and Cognitive Impairment Research
- Cerebrospinal fluid and hydrocephalus
- Cerebral Palsy and Movement Disorders
- Voice and Speech Disorders
- Myofascial pain diagnosis and treatment
- Facial Nerve Paralysis Treatment and Research
- Venous Thromboembolism Diagnosis and Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Parasitic infections in humans and animals
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurological Disease Mechanisms and Treatments
- Cervical and Thoracic Myelopathy
- Cerebrovascular and Carotid Artery Diseases
- Spine and Intervertebral Disc Pathology
- Multiple Sclerosis Research Studies
- Ocular Oncology and Treatments
- Endoplasmic Reticulum Stress and Disease
- Alzheimer's disease research and treatments
- Advanced Statistical Process Monitoring
- Gynecological conditions and treatments
- T-cell and Retrovirus Studies
- Trigeminal Neuralgia and Treatments
Universidade da Região de Joinville
2017-2021
Hospital Municipal São José
2016
Johannes Gutenberg University Mainz
2004-2006
Universidade Federal de Santa Catarina
2001-2003
Ihre-Radiologen
2001-2003
Hospital Regional de São José Dr. Homero de Miranda Gomes
2001
Mild cognitive impairment (MCI) is considered to be a transitional stage between normal aging and dementia. In Alzheimer’s disease (AD), white matter structural pathology due Wallerian degeneration central angiopathy. However, in MCI patients, the presence extent of alterations as possible correlate impaired memory function predictor subsequent progression AD not clarified yet. Diffusion tensor imaging (DTI) reveals ultrastructural integrity cerebral tracts. Therefore, it could detect...
Groundbreaking results concerning ischemic stroke (IS) hyperacute treatment worldwide were published in 2014 and 2015. We aimed to compare functional status after 3 months patients treated with intra-arterial thrombectomy (IAT) those intravenous thrombolysis (IVT) alone Joinville, Brazil. From the Joinville Stroke Registry, we extracted compared all consecutive IVT r-tPA within 4.5 h period 2009-2011 versus IAT 6 Solitaire FR device plus 2012-2014. registered 82 group 31 group. At hospital...
Objective – To assess whether serum S100B levels could reflect a glial response in patients with epilepsy secondary to neurocysticercosis (NCC) and idiopathic epilepsy. Subjects methods Serum were measured using an immunoluminometric assay 20 focal related chronic NCC (NCC group), 19 (EPI matched by epidemiological clinical data. Epileptic compared healthy controls (CON group) age sex. Results No difference was observed among NCC, EPI CON groups (P > 0.39). not affected antiepileptic drugs,...
Abstract The effect of quercetin on substance P‐induced plasma extravasation in rat urinary bladder and its modulation by endogenous peptidases conscious rats was studied. Plasma protein (PE) assayed measurement extravasated Evans blue dye (μg/g dry tissue). Intravenous injection P (SP, 10 nmol/kg) significantly increased PE the bladder. evoked SP (20 mg/kg, p.o.) pretreatment (73.5 ± 4.9 to 152.2 9.9). Pretreatment with captopril, an angiotensin‐converting enzyme (ACE) inhibitor (10...
ABSTRACT Superficial siderosis (SS) of the central nervous system (CNS) is a rare and possibly underdiagnosed disorder resulting from chronic or intermittent bleeding into subarachnoid space, leading to deposition blood products in subpial layers meninges. Magnetic resonance imaging (MRI) shows characteristic curvilinear pattern hypointensity on its blood-sensitive sequences. Methods Series cases collected Brazilian centers. Results We studied 13 patients presenting with progressive...
The present study was performed to: (a) evaluate the effects of kinin B1 (Sar[D-Phe8]-des-Arg9-BK; 10 nmol/kg) and B2 (bradykinin (BK); receptor agonists on plasma extravasation in selected rat tissues; (b) determine contribution a lipopolysaccharide (LPS) (100 microg/kg) to triggered by agonists; (c) characterize selectivity ([Leu8]desArg9-BK; (HOE 140; antagonists as inhibitors this kinin-induced phenomenon. were shown increase duodenum, ileum also urinary bladder rat. LPS pretreatment...
ABSTRACT Background: The Brazilian Committee for Treatment and Research in Multiple Sclerosis (BCTRIMS) has launched an initiative to determine the prevalence of multiple sclerosis (MS) Brazil, based on key cities deemed representative their regions terms demographic environmental features. Objective: To investigate rate MS Joinville. Methods: We reviewed medical records all patients who lived Joinville met 2010 McDonald's diagnostic criteria revised day (March 11, 2016). Potential included...
We describe a computational method to assist radiologists in performing better more reliable and simpler diagnosis of neurocysticercosis (NC). Based on this we implemented software system that counts measures the calcifications related NC computed tomography (CT) scans, thus reducing errors regarding visual inspection providing quantitative data. During computation, segments grey scale images obtained by CT scans resulting are submitted classification using artificial neural networks (ANNs)....
Problemstellung: Mikroangiopathische Läsionen des Hirngewebes sind mit der vaskulären subkortikalen Demenz korreliert. Die „erfahrungsdeterminierte” Beurteilung ist ungenügend, die Skalen kann zur replizierbaren Quantifizierung beitragen. Methodik: Von 9 Ärzten werden in einer zweimaligen weißen Hirnsubstanz (WML) Anzahl, Ausprägung und Lokalisation 10 MRT-Studien für 12 anatomisch definierte Regionen quantifiziert (Score). Aus den Scores Observer-Paare gebildet. Man erhält Observer Studien...
Pseudoathetosis is a movement disorder caused by loss of proprioception.The characterized involuntary, slow, and writhing movements.Multiple sclerosis (MS) an inflammatory demyelinating disease the central nervous system (CNS).The multiple lesions brain spinal cord.These are disseminated in time space.The onset neuroinflammation episodes neurological dysfunction that usually recover.Reports MS with pseudoathetosis extremely rare.The association these two disorders uncommon.This article shows...
Background: Aneurysmal subarachnoid hemorrhage (SAH) is a medical emergency characterized by extravasation of blood into the space after rupture cerebral aneurysm and presents high risk complications death. Case: A young patient (a previously healthy 32-year-old man) presented with SAH accompanied severe headache vasospasm (as shown on transcranial Doppler scan). The objective was to use integrative medicine treat his in an intensive care unit (ICU). Conventional traditional Chinese Medicine...
The possession of information about the structural organization brain white matter tracts by neurosurgical staff taking care patients with tumors can potentially increase quality interventions. We have developed a software system to execute in vivo fiber tractography using three dimensional tensor fields measured magnetic resonance diffusion imaging (MR-DTI) that be used normal clinical routine workflow, providing neurosurgeons very important patient data for operation planning and...