A5088090602- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Dementia and Cognitive Impairment Research
- Vestibular and auditory disorders
- Lysosomal Storage Disorders Research
- Alzheimer's disease research and treatments
- Fetal and Pediatric Neurological Disorders
- Parkinson's Disease Mechanisms and Treatments
- Cerebral Palsy and Movement Disorders
- Cerebrovascular and Carotid Artery Diseases
- Digital Radiography and Breast Imaging
- Hearing, Cochlea, Tinnitus, Genetics
- Health, Environment, Cognitive Aging
- Ophthalmology and Eye Disorders
- Tensor decomposition and applications
- Hemispheric Asymmetry in Neuroscience
- Porphyrin Metabolism and Disorders
- Traumatic Brain Injury Research
- Advanced Electron Microscopy Techniques and Applications
- Pharmaceutical studies and practices
- Dental Radiography and Imaging
- Data Quality and Management
- Advanced NMR Techniques and Applications
- Peripheral Nerve Disorders
Forschungszentrum Jülich
2021-2023
Düsseldorf University Hospital
2022
Heinrich Heine University Düsseldorf
2022
Society of Interventional Radiology
2021
Medizinische Hochschule Hannover
2014-2015
Johannes Gutenberg University Mainz
2004-2011
Klinik und Poliklinik für Neurologie
2009
Stuttgart Observatory
2008
Universidade Federal de Santa Catarina
2006
Medical University of Vienna
2005
Evaluating the extent of cerebral ischemic infarction is essential for treatment decisions and assessment possible complications in patients with acute stroke. Patients are often triaged according to image-based early signs infarction, defined by Alberta Stroke Program Early CT Score (ASPECTS). Our aim was evaluate interrater reliability a large group readers.We retrospectively analyzed 100 investigators who independently evaluated 20 non-contrast computed tomography (NCCT) scans as part...
Abstract Purpose: To present some unusual MR findings in a group of patients from the south‐west Dominican Republic suffering Pantothenate Kinase Associated Neurodegeneration (PKAN). Materials and Methods: Twenty one preclinical case homozygous for PANK2 mutation, 13 heterozygous gene carriers 14 healthy volunteers were scanned prospectively using 3 Tesla system. Results: All showed typical signal reduction within globus pallidus substantia nigra. A surprising finding was absence bright spot...
<h3>BACKGROUND AND PURPOSE:</h3> Knowledge of age-related physiological changes in the human brain is a prerequisite to identify neurodegenerative diseases. Therefore, this study whole-brain <sup>1</sup>H-MRS was used combination with quantitative MR imaging effects normal aging on healthy metabolites and microstructure. <h3>MATERIALS METHODS:</h3> Sixty volunteers, 21–70 years age, were studied. Brain maps NAA, creatine phosphocreatine, Cho tissue irreversible reversible transverse...
Abstract Purpose To differentiate fibroblastic meningiomas, usually considered to be of a hard consistency, from other benign subtypes using diffusion tensor imaging (DTI). Materials and Methods From DTI data sets 30 patients with we calculated tensors mean diffusivity (MD) fractional anisotropy (FA) maps as well barycentric representing the geometrical shape tensors. The findings were compared postoperative histology. study was approved by local ethics committee, informed consent given...
A feasibility study of an echo-planar spectroscopic imaging (EPSI) using a short echo time (TE) that trades off sensitivity, compared with other short-TE methods, to achieve whole brain coverage inversion recovery and spatial oversampling control lipid bleeding.Twenty subjects were scanned examine intersubject variance. One subject was five times intrasubject reproducibility. Data analyzed determine coefficients variance (COV) intraclass correlation coefficient (ICC) for N-acetylaspartate...
Fabry disease (FD) is a lysosomal storage disorder associated with marked cerebrovascular disease. Conventional MRI shows an extensive load of white matter lesions (WMLs) which may already be present at early stage in the disease.Investigator independent and sensitive quantification structural changes brain clinically affected men women FD.We performed voxel based analysis diffusion tensor images (DTI) 25 patients FD 20 age matched normal controls.DTI revealed significant increases cerebral...
To look for the presence and age-dependence of late structural alterations otherwise normal-appearing cerebral gray white matter after radiation chemotherapy in adult survivors acute lymphoblastic leukemia (ALL) during childhood.In a group 13 17-37 years old, who had been treated by total brain (18-24 Gy) 16-28 ago, prospective MR examinations including diffusion tensor imaging (DTI) were performed. Evaluation included volumetry, calculation mean diffusivity (MD) fractional anisotropy (FA),...
Abstract Differences in brain structure and functional structural network architecture have been found to partly explain cognitive performance differences older ages. Thus, they may serve as potential markers for these differences. Initial unimodal studies, however, reported mixed prediction results of selective variables based on features using machine learning (ML). the aim current study was investigate general validity from imaging data healthy adults. In particular, focus with examining...
To correlate the CT imaging findings of visibility and size vestibular aqueduct (VA) with degree cochlear hydrops determined in MRI late hydrops. Study Design: Retrospective study. Setting: Tertiary referral center. Patients: A total 127 patients (62 women, 65 men, average age 55.6 yrs): 86 these were diagnosed Menière's disease (American Academy Otolaryngology-Head Neck Surgery [AAO-HNS] criteria; 67 unilateral, 19 bilateral).Temporal bone performed all patients.Visibility/width VA temporal...
Structural brain imaging parameters may successfully predict cognitive performance in neurodegenerative diseases but mostly fail to abilities healthy older adults. One important aspect contributing this might be sex differences. Behaviorally, males and females have been found differ terms of profiles, which cannot captured by examining them as one homogenous group. In the current study, we examined whether prediction from structure, i.e. region-wise grey matter volume (GMV), would benefit...
The angular gyrus (AG) has been associated with multiple cognitive functions, such as language, spatial and memory functions. Since the AG is thought to be a cross-modal hub region suffering from significant age-related structural atrophy, it may also play key role in decline. However, exact relation between atrophy of decline older adults not fully understood, which related two aspects: First, cytoarchitectonically divided into areas, PGa PGp, potentially sub-serving different Second, adult...
The image diagnosis area is the biggest medical field in telemedicine, because it does not obligate a direct contact of patient with responsible radiologist during building report. persistent lack specialists places distant from urban centers makes telemedicine an important tool for improvement healthcare services. In this paper, we present framework, called CyclopsDistMedDB (Cyclops Distributed Medical Database), integration distributed DICOM record databases over wide areas. system has...