A5022129253- Multiple Sclerosis Research Studies
- Mycobacterium research and diagnosis
- Polyomavirus and related diseases
- Peripheral Neuropathies and Disorders
- Migraine and Headache Studies
- Musculoskeletal pain and rehabilitation
- Sphingolipid Metabolism and Signaling
- Neurosurgical Procedures and Complications
- Vector-borne infectious diseases
- Intensive Care Unit Cognitive Disorders
- Cerebrospinal fluid and hydrocephalus
- Mosquito-borne diseases and control
- Folate and B Vitamins Research
- Botulinum Toxin and Related Neurological Disorders
- Genetic Neurodegenerative Diseases
- Iron Metabolism and Disorders
- Cytokine Signaling Pathways and Interactions
- Acute Lymphoblastic Leukemia research
- Sympathectomy and Hyperhidrosis Treatments
- Chronic Lymphocytic Leukemia Research
- Hemoglobinopathies and Related Disorders
- Pain Mechanisms and Treatments
- Dementia and Cognitive Impairment Research
- Powdery Mildew Fungal Diseases
- Cervical and Thoracic Myelopathy
Sanofi (United States)
2021
Biogen (United States)
2018-2019
University of South Florida
2019
St. Josef-Hospital
2019
Universidade Federal Fluminense
1998-2018
Hospital Universitário Antônio Pedro
2007-2015
Instituto de Artes Visuais, Design e Marketing
2014
University of Oulu
2011
Universidade de São Paulo
2010
Sarah Network of Rehabilitation Hospitals
2007-2008
To assess functional changes in lymphocyte repertoire and subsequent clinical implications during delayed-release dimethyl fumarate (DMF) treatment patients with multiple sclerosis.Using peripheral blood from several trials of DMF, immune cell subsets were quantified using flow cytometry. For some patients, counts assessed after DMF discontinuation. Incidence adverse events, including serious opportunistic infections, was assessed.In DMF-treated absolute (ALCs) demonstrated a pattern decline...
ABSTRACT The expanding therapeutic arsenal in multiple sclerosis (MS) has allowed for more effective and personalized treatment, but the choice management of disease-modifying therapies (DMTs) is becoming increasingly complex. In this context, experts from Brazilian Committee on Treatment Research Multiple Sclerosis Neuroimmunology Scientific Department Academy Neurology have convened to establish Consensus MS, based their understanding that neurologists should be able prescribe MS DMTs...
Objective Cognitive dysfunction is common in multiple sclerosis. The Brief Repeatable Battery of Neuropsychological Tests (BRB-N) was developed to assess cognitive functions most-frequently impaired However, normative values are lacking Brazil. Therefore, we aimed provide continuous and discrete for the BRB-N a Brazilian population sample. Methods We recruited 285 healthy individuals from community at 10 sites applied version A 237 participants B 48 participants. Continuous norms were...
The long-term safety of dimethyl fumarate (DMF) in patients with relapsing-remitting multiple sclerosis (RRMS) has been studied mainly Caucasian patients. present interim analysis aimed to evaluate the 72-week DMF Japanese RRMS. Safety data subjects enrolled 24-week randomised, double-blind, placebo-controlled APEX study (Part I) and its following open-label extension II) were analysed at 72 weeks from beginning Part I. In I, randomised treatment or matching placebo while all received during...
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Asperger syndrome (AS) is a neurobiological condition which characterized by poor skills in social communication, and restricted repetitive patterns of behavior interests. We studied whether stress-related indices heart rate variability (HRV) electroencephalography (EEG) are different children with AS than normal controls. analyzed retrospectively the data test where audiovisual stimuli were used. hypothesized that this stressful situation for individuals they would have greater reaction...
Fingolimod is a new and efficient treatment for multiple sclerosis (MS). The drug administration requires special attention to the first dose, since cardiovascular adverse events can be observed during initial six hours of fingolimod ingestion. present study consisted review data on 180 patients with MS receiving dose fingolimod. rate bradycardia in these was higher than that clinical trials very strict inclusion criteria patients. There were less 10% cases requiring attention, but no fatal...
BACKGROUND: Fampridine is a broad-spectrum voltage-dependent potassium channel blocker that enhances synaptic transmission. The drug has been shown to be able ameliorate conduction in demyelinated axons, thereby leading improved gait patient
Dissection of cervical arteries constitutes a medical emergency. Although relatively rarely, activities classified as sports and recreation may be cause arterial dissection independently neck or head trauma. The purpose the present paper was to series cases cerebrum-cervical in individuals during soon after practice these activities.Retrospective data on patients with related recreation.Forty-one were identified. most frequently affected vessel vertebral artery. A large variety had temporal...
Children with cerebral palsy (CP) may present varied ophthalmological problems. Paradoxically, however, investigation of visual function and possible related disorders is not routinely conducted in this population during medical consultations.This paper proposes a simple, practical guide for assessing vision ocular motricity children CP. One-hundred twenty-three patients (mean age: 8.4 years +/- 2.3) from the Sarah Network Rehabilitation Hospitals (Brasilia, Rio de Janeiro São Luis units)...
INTRODUÇÃO: A cefaléia do tipo tensional (CTT), dor cefálica mais comum, tem mecanismos fisiopatológicos, epidemiologia e apresentação clínica pouco estudados. Depressão ansiedade são comorbidades especialmente enfocadas entre seus portadores. OBJETIVO: Estudar a ocorrência de sintomas depressivos portadores CTT episódica (CTTE) crônica (CTTC). METODOLOGIA: Cinqüenta pacientes com CTTE cinqüenta CTTC preencheram os inventários depressão Beck. Somente foram considerados aqueles escores...
Com o objetivo de estudar os aspectos clínicos, a história familiar e impacto da dor nas atividades laborativas, foi conduzido estudo série casos 50 pacientes portadores cefaléia do tipo tensional episódica (CTTE). Foram avaliados 40 mulheres 10 homens, com idade média 30 (±12) anos. Dor constrictiva esteve presente em (80%). O enjôo principal fenômeno acompanhante (20%). A bilateral predominou; entretanto, localização unilateral também (10%). Embora classicamente descrita como uma leve,...
Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective the present study was to assess serum vitamin levels a large population patients with MS controls living restricted tropical area.Data from 535 350 control subjects were obtained 14 cities around Tropic Capricorn.The mean 25-OH level 26.07 ± 10.27 ng/mL for subjects, 28.03 12.19 MS. No correlation observed between disability over disease duration.At least region Capricorn, typically are...
The objectives of this study were to assess the prevalence temporomandibular disorders (TMDs) in patients with relapsing-remitting multiple sclerosis (MS) and investigate whether an association exists between presence TMD symptoms degree MS-related disability.In all, 120 individuals evaluated: 60 a diagnosis MS age- sex-matched controls without neurological impairments. A questionnaire recommended by European Academy Craniomandibular Disorders for assessment was administered. For those who...